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ODN 1826 sodium (CpG 1826 sodium)

Cat.No.P1246

ODN 1826 sodium (CpG 1826 sodium) is a synthetic CpG oligodeoxynucleotide and agonist of TLR9 signaling pathway, that induces G1-phase arrest and apoptosis in A20 lymphoma cells while stimulating NO and iNOS production in mouse models, as part of its immunostimulatory activity.

Amino-acid Sequence

CAS No.

Quality Control

Featured Inhibitors	Y-27632 Dihydrochloride SB431542 CHIR-99021 (Laduviglusib) RMC-7977 RMC-6236 (Daraxonrasib) MRTX1133 MG132 Z-VAD-FMK VT3989 IAG933

Chemical Information & Solubility

Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

In vivo
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Biological Activity

Description	ODN 1826 sodium (CpG 1826 sodium) is a synthetic CpG oligodeoxynucleotide and agonist of TLR9 signaling pathway, that induces G1-phase arrest and apoptosis in A20 lymphoma cells while stimulating NO and iNOS production in mouse models, as part of its immunostimulatory activity.
Targets/IC₅₀/Ki	TLR9

References
https://pubmed.ncbi.nlm.nih.gov/23357786/ https://pubmed.ncbi.nlm.nih.gov/12067301/

References

https://pubmed.ncbi.nlm.nih.gov/23357786/
https://pubmed.ncbi.nlm.nih.gov/12067301/

Product Information

Molecular Weight	6804
Shipping	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)