For research use only. Not for use in humans.

Nurulimab (Anti-CTLA-4 / CD152)

Synonyms: null Cat.No.A2859 Purity:99%

Nurulimab (Anti-CTLA-4 / CD152) is a monoclonal antibody directed against the human T-cell-expressed receptor cytotoxic T-lymphocyte-associated antigen 4 (CTLA4, CTLA-4), with potential immune checkpoint inhibitory and antineoplastic activities. MW: 145.34 KD.

Quality Control

Batch: A285901 Purity: 99% Protein concentration: 5.378mg/ml Endotoxin Level: ＜1EU/mg

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COA
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Datasheet

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Nurulimab (Anti-CTLA-4 / CD152) is a monoclonal antibody directed against the human T-cell-expressed receptor cytotoxic T-lymphocyte-associated antigen 4 (CTLA4, CTLA-4), with potential immune checkpoint inhibitory and antineoplastic activities. MW: 145.34 KD.
References	[1] https://cdn.who.int/media/docs/default-source/international-nonproprietary-names-(inn)/rl83.pdf?sfvrsn=e0ecc927_11&download=true

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	2168561-20-2
Molecular Weight	145.34
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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