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Nicotinamide is a NAD+ precursor and SIRT1 inhibitor. It affects SIRT1/NF-κB signaling by boosting NAD+, inhibiting apoptosis.
Nicotinamide (Niacinamide): Mechanism of Action
Nicotinamide (Niacinamide) MOA：Targeting Melanosome/Melanogenesis Pathway for Dermatology and Cosmeceuticals
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