Nicotinamide is a NAD+ precursor and SIRT1 inhibitor. It affects SIRT1/NF-κB signaling by boosting NAD+, inhibiting apoptosis.
Comprehensive IC50 Values for Nicotinamide (Niacinamide) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
Nicotinamide is a NAD+ precursor and SIRT1 inhibitor. It affects SIRT1/NF-κB signaling by boosting NAD+, inhibiting apoptosis.