|
PC-3-hLuc-PSMA cells
|
129.9 ng
|
Cell counting kit-8 assay, determined using GraphPadPrism software.
|
PMC12329190
|
|
BXPC-3 cells
|
0.128 nM
|
CCK8 viability assays, nonlinear logistic regression
|
PMC9463470
|
|
HEK-293 (pcDNA)
|
0.90 nM
|
CellTiter Glo reagent to assess GI50 values.
|
Download PDF
|
|
HEK-293 (MDR-19)
|
360 nM
|
CellTiter Glo reagent to assess GI50 values.
|
Download PDF
|
|
HEK-293 (R-5)
|
5.1 nM
|
CellTiter Glo reagent to assess GI50 values.
|
Download PDF
|
|
HEK-293 (MRP1)
|
1.2 nM
|
CellTiter Glo reagent to assess GI50 values.
|
Download PDF
|
|
4T1 cells
|
500 nM
|
CellTiter-Blue cell viability assay
|
Download PDF
|
|
MDA-MB-231 cells
|
120 nM
|
CellTiter-Blue cell viability assay
|
Download PDF
|
|
786-O
|
5.9E-9 M
|
MTT assays
|
Download PDF
|
|
HT-29
|
5.8E-10 M
|
MTT assays
|
Download PDF
|
|
NCI-H292
|
4.0E-10 M
|
MTT assays
|
Download PDF
|
|
SUM149PT
|
1.8E-10 M
|
MTT assays
|
Download PDF
|
|
Molm13-Luciferase cells
|
< 0.5 nM
|
luciferase-based assay
|
Download PDF
|
|
AGS cells
|
8.2 nM
|
CCK-8 kit
|
PMC12632142
|
|
Karpas299
|
25.6 nM
|
Cell Counting Kit-8 (CCK-8) assay
|
Download PDF
|
|
Daudi
|
>1 µM
|
Cell Counting Kit-8 (CCK-8) assay
|
Download PDF
|
|
HL-60
|
51.7 nM
|
Cell Counting Kit-8 (CCK-8) assay
|
Download PDF
|
|
Jurkat
|
80.2 nM
|
Cell Counting Kit-8 (CCK-8) assay
|
Download PDF
|
|
HuT78
|
39.7 nM
|
Cell Counting Kit-8 (CCK-8) assay
|
Download PDF
|
|
H929
|
>1 µM
|
Cell Counting Kit-8 (CCK-8) assay
|
Download PDF
|
|
MX-1
|
6 ng/mL
|
Cell viability assay in spheroid conditions
|
PMC10551938
|
|
SKBR3
|
10 ng/mL
|
Cell viability assay in spheroid conditions
|
PMC10551938
|
|
MDA-MB-468
|
77 ng/mL
|
Cell viability assay in spheroid conditions
|
PMC10551938
|
|
MDA-MB-231
|
>1000 ng/mL
|
Cell viability assay in spheroid conditions
|
PMC10551938
|
|
SNU46
|
115.4 nM
|
MTT assay
|
PMC11448212
|
|
SNU899
|
73.56 nM
|
MTT assay
|
PMC11448212
|
|
U87MG
|
0.23 nM
|
Cell viability determined by MTT assay, absorbance measured at λ=570 nm, normalized versus untreated control samples and interpolated by nonlinear regression analysis with GraphPad Prism 6 software to generate sigmoidal dose-response curves.
|
Download PDF
|
|
SK-OV-3
|
0.03 nM
|
Cell viability determined by MTT assay, absorbance measured at λ=570 nm, normalized versus untreated control samples and interpolated by nonlinear regression analysis with GraphPad Prism 6 software to generate sigmoidal dose-response curves.
|
Download PDF
|
|
PC3pip
|
12.6 ±1.1 nM
|
CellTiter 96 Aqueous One Solution Cell Proliferation Assay
|
Download PDF
|
|
PC3flu
|
46.6 ±3.2 nM
|
CellTiter 96 Aqueous One Solution Cell Proliferation Assay
|
Download PDF
|
|
HT29 cells
|
8.3 nM
|
MTS assay
|
Download PDF
|
|
MCF-7 cells
|
8.8 nM
|
MTS assay
|
Download PDF
|
|
U87-MG cells
|
67.8 nM
|
MTS assay
|
Download PDF
|
|
EL-4 lymphoma
|
292±85 pM
|
MTT assay
|
PMC9240879
|
|
B78-D14 melanoma
|
442±170 pM
|
MTT assay
|
PMC9240879
|
|
IMR-32 neuroblastoma
|
below 1 nM
|
MTT assay
|
PMC9240879
|
|
T98G glioma
|
below 1 nM
|
MTT assay
|
PMC9240879
|
|
U2OS osteosarcoma
|
below 1 nM
|
MTT assay
|
PMC9240879
|
|
Hs578T breast cancer
|
below 1 nM
|
MTT assay
|
PMC9240879
|
|
COLO-38 melanoma
|
below 1 nM
|
MTT assay
|
PMC9240879
|
|
mS melanoma
|
below 1 nM
|
MTT assay
|
PMC9240879
|
|
NCI-N87
|
0.460 nM
|
MTT (3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay
|
Download PDF
|
|
MCF-7
|
81.4 nM
|
MTT (3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay
|
Download PDF
|
|
MDA-MB-468
|
5.01 nM
|
MTT (3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay
|
Download PDF
|
|
Capan-2
|
26 nM
|
colony formation assay
|
Download PDF
|
|
CFPAC-1
|
50 nM
|
colony formation assay
|
Download PDF
|
|
PANC-1
|
59 nM
|
colony formation assay
|
Download PDF
|
|
Melanoma cells (UACC-257)
|
0.4 ± 7.2 nM
|
Mitochondrial dehydrogenase activity measurement using a specific dye; OD570/OD605 nm ratio
|
Download PDF
|
|
NCI-N87
|
1.51 nM (Fc-U-Z HER2 -MMAE), 0.65 nM (Herceptin-MMAE), 11.1
|
MTT assay
|
Download PDF
|
|
SK-BR-3
|
0.55 nM (Fc-U-Z HER2 -MMAE), 0.43 nM (Herceptin-MMAE), 0.73
|
MTT assay
|
Download PDF
|
|
BT-474
|
0.34 nM (Fc-U-Z HER2 -MMAE), 0.87 nM (Herceptin-MMAE), 2.10
|
MTT assay
|
Download PDF
|
|
SK-OV-3
|
41.2 nM (Fc-U-Z HER2 -MMAE), 56.5 nM (Herceptin-MMAE), 62.5
|
MTT assay
|
Download PDF
|
|
H-CC70
|
> 500 nM
|
MTT assay
|
Download PDF
|
|
NOVC7C
|
0.372 nM
|
Luminescent Cell Viability Assay Kit
|
PMC9679668
|
|
OVCAR3
|
0.286 nM
|
Luminescent Cell Viability Assay Kit
|
PMC9679668
|
|
OVCAR3-LUC
|
0.167 nM
|
Luminescent Cell Viability Assay Kit
|
PMC9679668
|
|
ES2
|
0.330 nM
|
Luminescent Cell Viability Assay Kit
|
PMC9679668
|
|
MDA-MB-468 cells
|
(3.20 ± 0.60) nmol/L
|
CCK-8 assay
|
Download PDF
|
|
MDA-MB-231 cells
|
(6.60 ± 0.50) nmol/L
|
CCK-8 assay
|
Download PDF
|
|
22Rv1
|
0.21 ± 0.03 kBq/mL
|
Colony-forming assay
|
PMC13080322
|
|
MM.1S
|
4.7 ± 0.7 pmol/L (for R-ADC); 197 ± 44.2 pmol/L (for YS5-MMA
|
assay, Clonogenic assay
|
PMC13080322
|
|
22Rv1
|
5.8 ± 0.9 Bq/mL (at 6.3 kBq/μg); 1.8 ± 0.6 Bq/mL (at 3.44 kB
|
Colony-forming assay
|
PMC13080322
|
|
NCI-N87
|
0.2-1.93 nM
|
assay kit (CTG), 4-variable curve analysis by OriginPro 2018
|
Download PDF
|
|
BT474
|
0.2-1.93 nM
|
assay kit (CTG), 4-variable curve analysis by OriginPro 2018
|
Download PDF
|
|
MDA-MB-361
|
0.2-1.93 nM
|
assay kit (CTG), 4-variable curve analysis by OriginPro 2018
|
Download PDF
|
|
MDA-MB-453
|
0.2-1.93 nM
|
assay kit (CTG), 4-variable curve analysis by OriginPro 2018
|
Download PDF
|
|
MCF7
|
0.2-1.93 nM
|
assay kit (CTG), 4-variable curve analysis by OriginPro 2018
|
Download PDF
|
|
MDA-MB-231
|
0.2-1.93 nM
|
assay kit (CTG), 4-variable curve analysis by OriginPro 2018
|
Download PDF
|
|
SKOV3
|
0.2-1.93 nM
|
assay kit (CTG), 4-variable curve analysis by OriginPro 2018
|
Download PDF
|
|
NCI-N87-HDR
|
0.2-1.93 nM
|
assay kit (CTG), 4-variable curve analysis by OriginPro 2018
|
Download PDF
|
|
BT474-HDR
|
0.2-1.93 nM
|
assay kit (CTG), 4-variable curve analysis by OriginPro 2018
|
Download PDF
|
|
A431 monolayers
|
236 pM
|
Total cellular red signal obtained by live cell imaging
|
Download PDF
|
|
A431 spheroids (800 cells)
|
493 pM
|
Total cellular red signal obtained by live cell imaging
|
Download PDF
|
|
T47D
|
0.22 nM
|
assays; nonlinear regression analysis of concentration response curves using GraphPad Prism 6.0
|
Download PDF
|
|
CAMA1
|
5.2 nM
|
assays; nonlinear regression analysis of concentration response curves using GraphPad Prism 6.0
|
Download PDF
|
|
BT-474
|
0.56 nM
|
assays; nonlinear regression analysis of concentration response curves using GraphPad Prism 6.0
|
Download PDF
|
|
MCF7
|
> 22 nM
|
assays; nonlinear regression analysis of concentration response curves using GraphPad Prism 6.0
|
Download PDF
|
|
MDA-MB-361
|
0.96 nM
|
assays; nonlinear regression analysis of concentration response curves using GraphPad Prism 6.0
|
Download PDF
|
|
SKBR3
|
3.67 nM
|
assays; nonlinear regression analysis of concentration response curves using GraphPad Prism 6.0
|
Download PDF
|
|
UACC812
|
> 22 nM
|
assays; nonlinear regression analysis of concentration response curves using GraphPad Prism 6.0
|
Download PDF
|
|
MDA-MB-231
|
> 22 nM
|
assays; nonlinear regression analysis of concentration response curves using GraphPad Prism 6.0
|
Download PDF
|
|
22RV1
|
> 22 nM
|
assays; nonlinear regression analysis of concentration response curves using GraphPad Prism 6.0
|
Download PDF
|
|
AN3CA
|
22 nM
|
assays; nonlinear regression analysis of concentration response curves using GraphPad Prism 6.0
|
Download PDF
|
|
SMOV2
|
> 22 nM
|
assays; nonlinear regression analysis of concentration response curves using GraphPad Prism 6.0
|
Download PDF
|
|
SW403
|
17 nM
|
assays; nonlinear regression analysis of concentration response curves using GraphPad Prism 6.0
|
Download PDF
|
|
HepG2
|
> 22 nM
|
assays; nonlinear regression analysis of concentration response curves using GraphPad Prism 6.0
|
Download PDF
|
|
HuH-7
|
> 22 nM
|
assays; nonlinear regression analysis of concentration response curves using GraphPad Prism 6.0
|
Download PDF
|
|
NCI-N87 cells
|
83.68 nM
|
WST-1 proliferation assays
|
Download PDF
|
|
NCI-H1781
|
0.0003 µM
|
[Vendor] luminescent reagent
|
Download PDF
|
|
SW900
|
0.0003 µM
|
[Vendor] luminescent reagent
|
Download PDF
|
|
HCC1569
|
0.0003 µM
|
[Vendor] luminescent reagent
|
Download PDF
|
|
BR-05-028
|
0.0003 µM
|
[Vendor] luminescent reagent
|
Download PDF
|
|
BR-05-014E
|
0.0003 µM
|
[Vendor] luminescent reagent
|
Download PDF
|
|
HBCx8
|
0.0003 µM
|
[Vendor] luminescent reagent
|
Download PDF
|
|
Kuramochi
|
0.0003 µM
|
[Vendor] luminescent reagent
|
Download PDF
|
|
MES-SA
|
0.0003 µM
|
[Vendor] luminescent reagent
|
Download PDF
|
|
MES-SA/Dx5
|
0.009 µM
|
[Vendor] luminescent reagent
|
Download PDF
|
|
MDA-MB-231
|
4.70x10-10 M
|
XTT assay
|
PMC6401411
|
|
HEK-293 pcDNA
|
0.90 nM
|
Three-day cytotoxicity assays, CellTiter Glo reagent to assess GI50 values.
|
Download PDF
|
|
HEK-293 MDR-19
|
360 nM
|
Three-day cytotoxicity assays, CellTiter Glo reagent to assess GI50 values.
|
Download PDF
|
|
HEK-293 R-5
|
5.1 nM
|
Three-day cytotoxicity assays, CellTiter Glo reagent to assess GI50 values.
|
Download PDF
|
|
HEK-293 MRP1
|
1.2 nM
|
Three-day cytotoxicity assays, CellTiter Glo reagent to assess GI50 values.
|
Download PDF
|
|
BxPC-3
|
0.310 nM
|
Cell viability assay
|
PMC8340053
|
|
KP-2
|
0.288 nM
|
Cell viability assay
|
PMC8340053
|
|
PK-8
|
0.334 nM
|
Cell viability assay
|
PMC8340053
|
|
TE8
|
0.304 nM
|
Cell viability assay
|
PMC8340053
|
|
TE14
|
0.296 nM
|
Cell viability assay
|
PMC8340053
|
|
KYSE70
|
0.349 nM
|
Cell viability assay
|
PMC8340053
|
|
BxPC-3 GPC1-KO
|
0.317 nM
|
Cell viability assay
|
PMC8340053
|
|
TE8 GPC1-KO
|
0.336 nM
|
Cell viability assay
|
PMC8340053
|
|
mesothelin-expressing cancer cells
|
0.17-0.2 nM
|
cell proliferation assay
|
PMC5080863
|
|
BxPC-3
|
0.97 nM
|
Cell Counting Kit-8
|
PMC5024081
|
|
PSN-1
|
0.99 nM
|
Cell Counting Kit-8
|
PMC5024081
|
|
Capan-1
|
1.10 nM
|
Cell Counting Kit-8
|
PMC5024081
|
|
Panc-1
|
1.16 nM
|
Cell Counting Kit-8
|
PMC5024081
|
|
THP-1
|
156.0 nM
|
XTT cell viability assay, non-linear regression test with Hill-3 parameter adjustment
|
Download PDF
|
|
SKM-1
|
105.8 nM
|
XTT cell viability assay, non-linear regression test with Hill-3 parameter adjustment
|
Download PDF
|
|
HT1080 fibrosarcoma cells
|
15 pM
|
resazurin-based cytotoxicity assay
|
PMC6307086
|
|
U-2932
|
0.33±0.14 ng/mL
|
colorimetric cell proliferation kit (XTT)
|
PMC7944372
|
|
SUDHL-2
|
0.50±0.08 ng/mL
|
colorimetric cell proliferation kit (XTT)
|
PMC7944372
|
|
Toledo
|
0.87±0.09 ng/mL
|
colorimetric cell proliferation kit (XTT)
|
PMC7944372
|
