MMAE (Monomethyl auristatin E) is a potent microtubule inhibitor. It affects microtubule dynamics signaling by binding to and disrupting the microtubule network, effectively inducing G2/M cell cycle arrest and apoptosis in cancer cells.
Comprehensive IC50 Values for MMAE (Monomethyl auristatin E) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
MMAE (Monomethyl auristatin E) is a potent microtubule inhibitor. It affects microtubule dynamics signaling by binding to and disrupting the microtubule network, effectively inducing G2/M cell cycle arrest and apoptosis in cancer cells.