SMILES:

COC1=C(NC(=O)C2=CC=CN=C2C)C3=C(C=C1Cl)C4=C([NH]3)C=NC=C4
MLN120B Chemical Structure
Chemical Structure
Check the MLN120B product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylpyridine-3-carboxamide
CAS Number 783348-36-7
Molecular Formula

C19H15ClN4O2
Molecular Weight (MW) 366.80
SMILES COC1=C(NC(=O)C2=CC=CN=C2C)C3=C(C=C1Cl)C4=C([NH]3)C=NC=C4
InChIKey ZNOLRTPMNMPLHY-UHFFFAOYSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 73 mg/mL (199.01 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 5 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.