MK-2206 Dihydrochloride is a potent, selective, allosteric Akt inhibitor. It affects the PI3K/Akt/mTOR signaling pathway by blocking Akt phosphorylation, to inhibit tumor cell proliferation, migration, angiogenesis, and promote apoptosis.
MK-2206 Dihydrochloride IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for MK-2206 Dihydrochloride Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.