PD0325901 (Mirdametinib): Selectivity & Specificity
PD0325901 (Mirdametinib) is a potent inhibitor of MEK1 (0.33 nM), MEK2 (0.33 nM), ERK, p-ERK, ERK1/2. PD0325901 (Mirdametinib) exhibits the greatest inhibitory potency toward MEK1 and MEK2 (IC50 = 0.33 nM).