Home Biosimilar Antibodies Protein Tyrosine Kinase Axl Mipasetamab (Anti-AXL / UFO)
For research use only. Not for use in humans.

Mipasetamab (Anti-AXL / UFO)

Synonyms: null

Mipasetamab (Anti-AXL / UFO) is a human monoclonal IgG1κ antibody targeting AXL, a tyrosine kinase receptor, and an TAM receptor, which involves the synthesis of ADCT-601 (Mipasetamab uzoptirine), an AXL-targeted antibody-drug conjugate (ADC). MW: 145.78 kD.

Mipasetamab (Anti-AXL / UFO)

Quality Control

Batch: A277401 Purity: 99% Protein concentration: Endotoxin Level: ＜1EU/mg
99

Specificity

Name Citation Axl Others
BMS-777607 63 RON,Met,Tyro3
Bemcentinib (R428) 131
XL092 0 VEGFR2,MER,MET
UNC2025 7 FLT3,Mer,TrkA
Ningetinib 0 VEGFR2,c-Met
Tamnorzatinib (ONO-7475) 4 Mer,FLT3
RU-301 0
Sitravatinib (MGCD516) 7 DDR2,EPHA3,Mer
CEP-40783 (RXDX-106) 7 c-Met,Tyro3,MER
S49076 1 Met,Mer,FGFR3
Merestinib (LY2801653) 11 DDR1,Met,DDR2
SGI-7079 4 YES,Mer,Met
UNC2025 HCl 9 Mer,FLT3,Tyro3
Dubermatinib(TP-0903) 19
NPS-1034 3 Met
LDC1267 9 Mer,Tyro3
PF-07265807 0 Mer
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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Mipasetamab (Anti-AXL / UFO) is a human monoclonal IgG1κ antibody targeting AXL, a tyrosine kinase receptor, and an TAM receptor, which involves the synthesis of ADCT-601 (Mipasetamab uzoptirine), an AXL-targeted antibody-drug conjugate (ADC). MW: 145.78 kD.
References

Product Details

CAS No. 2361055-48-1
Molecular Weight 145.78
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Tech Support

Handling Instructions

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