Molecular Weight: 570.64 g/mol
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Chemical Structure
Check the
Midostaurin (PKC412)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(175.24 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 2 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(175.24 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(175.24 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 32 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(175.24 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 20 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(175.24 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 39 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
| IUPAC Name | N-[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-N-methylbenzamide | |
|---|---|---|
| CAS Number | 120685-11-2 | |
| Molecular Formula |
C35H30N4O4 |
|
| Molecular Weight (MW) | 570.64 | |
| SMILES | CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC | |
| InChIKey | BMGQWWVMWDBQGC-IIFHNQTCSA-N |
- Midostaurin (PKC412) Mechanism of Action: FLT3 Inhibition in Leukemic Blast Cells Research
- Midostaurin (PKC412) Clinical Trials
- Midostaurin (PKC412) Solubility in DMSO
- Midostaurin (PKC412) Stock Solution
- Midostaurin (PKC412) Storage
- Midostaurin (PKC412) Stability
- Midostaurin (PKC412) SMILES
- Midostaurin (PKC412) CAS Number
- Midostaurin (PKC412) Chemical Structure (2D and 3D)
- Midostaurin (PKC412) Sigma (569397)? Try a better option.
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- Midostaurin (PKC412) Cayman (10459)? Try a better option.
- Midostaurin (PKC412) APExBIO (B3709)? Try a better option.
- Midostaurin (PKC412) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.