For research use only. Not for use in humans.

Lusvertikimab (Anti-IL-7Ra / CD127)

Synonyms: OSE-127 Cat.No.A2669 Purity:99%

Lusvertikimab (Anti-IL-7Ra / CD127) is a humanized monoclonal antibody targeting IL7R. It has anti-leukemic efficacy and has the potential for B cell precursor acute lymphoblastic leukemia (BCP-ALL) research. MW :145.64 KD.

Quality Control

Batch: A266901 Purity: 99% Protein concentration: 8.873mg/ml Endotoxin Level: ＜1EU/mg

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COA
SDS
Datasheet

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Lusvertikimab (Anti-IL-7Ra / CD127) is a humanized monoclonal antibody targeting IL7R. It has anti-leukemic efficacy and has the potential for B cell precursor acute lymphoblastic leukemia (BCP-ALL) research. MW :145.64 KD.
References	[1] https://ashpublications.org/blood/article/140/Supplement%201/1045/490434/The-IL7R-Antagonist-OSE-127-Blocks-Acute

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	2375835-91-7
Molecular Weight	145.64
Isotype	Human IgG4SP
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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