Cell-free Assays (IC50/Ki) for Leptomycin B (LMB)
| Key Target | IC50 (Cell-free) | Description | Reference |
|---|---|---|---|
| No published data available. | |||
Cell-based Assay (IC50) for Leptomycin B (LMB)
| Cell Type | IC50 (Cell-based) | Description | Reference |
|---|---|---|---|
| A549 | 10.6 nM | MTT assay, Probit analysis | Download PDF |
| A549 | 4.4 nM | MTT assay, Probit analysis | Download PDF |
| A2780CP | ~4 nM | Clonogenic assay | Download PDF |
| ECC-1 | ~4 nM | Clonogenic assay | Download PDF |
| U2OS | 0.16 nM | Rev-GFP assay | Download PDF |
| MM.1S | 0.46 nM | MTT assay | Download PDF |
| HCT-116 | 0.19 nM | MTT assay | Download PDF |
| AML2 | 0.39 nM | MTT assay | Download PDF |
| AML3 | 0.68 nM | MTT assay | Download PDF |
| MM.1S | 0.27 nM | XPO1 occupancy assay (Simple Western detection) | Download PDF |
Check the
Leptomycin B (LMB)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
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