For research use only. Not for use in humans.

Lecanemab (Anti-Amyloid Beta)

Synonyms: BAN-2401

Lecanemab (Anti-Amyloid Beta) is a humanized IgG1 monoclonal antibody targeting soluble aggregated amyloid beta (Aβ). It can be used for the research of Alzheimer's Disease. MW :147.06 KD.

Lecanemab (Anti-Amyloid Beta)

1 Citation

The Nobel Prize

17 Nobel Prize winners have used Selleck products

Shimon Sakaguchi

Nature Communications 2025,16, Article number:1325

David Baker

Dev Cell 2023, 58(20):2163-2180.e9.

David Julius

Cell 2017, 185-198.e16

Michael Houghton

Cell Chem Biol, 2020, 27(7):780-792.e5

Charles M. Rice

Cell 2018, 172(3):423-438.e25

Quality Control

Batch: Purity: 99% Protein concentration: 5.451mg/ml Endotoxin Level: <1EU/mg
99

Specificity

Name Citation Beta Amyloid Others
DAPT 398 Notch
RO4929097 (RG-4733) 124 γ secretase,Notch
Semagacestat (LY450139) 22 Notch
MK-0752 23
Avagacestat (BMS-708163) 22
LY2811376 19 BACE1
CRANAD-2 0
Hoechst 34580 1
Frentizole 0
Simufilam 0
Ginsenoside Rg1 5 NF-κB
Ginsenoside Re 1 NF-κB,JNK
Tabersonine hydrochloride 0
EUK 134 6
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Lecanemab (Anti-Amyloid Beta) is a humanized IgG1 monoclonal antibody targeting soluble aggregated amyloid beta (Aβ). It can be used for the research of Alzheimer's Disease. MW :147.06 KD.
References

Product Details

CAS No. 1260393-98-3
Isotype Human IgG1
Source CHO
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Tech Support

Handling Instructions

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