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LDN-193189 SDS | MSDS

1.PRODUCT AND COMPANY IDENTIFICATION

Product identifier

  • Product Name: LDN-193189
  • Catalog Number: S2618
  • CAS Number: 1062368-24-4
  • IUPAC Name: 4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline

Relevant identified uses and uses advised against

  • Identified uses: For research and development use only; laboratory chemicals; manufacture of substances.
  • Uses advised against: Not for pharmaceutical, household, or other unapproved uses.

Details of the supplier

  • Company : Selleck Chemicals
  • TollFree : +1 877 796-6397
  • Tel : +1 832 582-8158
  • Fax : +1 832 582-8590

Emergency telephone number

  • Emergency phone #: +1 832 582-8158

2. Hazard(s) identification

  • Classification of the substance or mixture: The substance is not classified according to the Globally Harmonized System (GHS).
  • Label elements:
    • GHS label elements: None
    • Hazard pictograms: None
    • Signal word: None
    • Hazard statements: None
  • Information pertaining to particular dangers for man and environment: No specific data provided for this section.
  • Classification system:
    • NFPA ratings (scale 0 - 4): Health = 0, Fire = 0, Reactivity = 0.
    • HMIS-ratings (scale 0 - 4): Health = 0, Fire = 0, Reactivity = 0.
  • Other hazards:
    • Results of PBT and vPvB assessment: PBT: Not applicable; vPvB: Not applicable.
  • Classification according to (d)(1)(ii) of § 1910.1200: The SDS issuer does not object to the classifications provided by importers or manufacturers of precursor products.
  • Hazards not otherwise classified: There are no adverse physical or health effects known that are not covered by the hazard classes of the Hazard Communications Standard.

3. Composition/information on ingredients

  • Chemical characterization: Substances
  • CAS No. Description: 1062368-24-4 LDN-193189

4. First-aid measures

  • Description of first aid measures:
    • General information: No special measures required.
    • After inhalation: Supply fresh air; consult a doctor in case of complaints.
    • After skin contact: Generally the product does not irritate the skin.
    • After eye contact: Rinse opened eye for several minutes under running water.
    • After swallowing: If symptoms persist, consult a doctor.
  • Most important symptoms and effects, both acute and delayed: No further relevant information available.
  • Indication of any immediate medical attention and special treatment needed: No further relevant information available.

5. Fire-fighting measures

  • Extinguishing media:
    • Suitable extinguishing agents: Use fire-fighting measures that suit the environment. A solid water stream may be inefficient.
  • Special hazards arising from the substance or mixture: No further relevant information available.
  • Advice for firefighters:
    • Protective equipment: No special measures required.

6. Accidental release measures

  • Personal precautions, protective equipment and emergency procedures: Not required.
  • Environmental precautions: Do not allow to enter sewers, surface, or ground water.
  • Methods and material for containment and cleaning up: Pick up mechanically.
  • Protective Action Criteria for Chemicals:
    • PAC-1: Substance is not listed.
    • PAC-2: Substance is not listed.
    • PAC-3: Substance is not listed.
  • Reference to other sections: See Section 7 for information on safe handling, Section 8 for information on personal protection equipment, and Section 13 for disposal information.

7. Handling and storage

  • Precautions for safe handling: No special measures required.
  • Information about protection against explosions and fires: No special measures required.
  • Conditions for safe storage, including any incompatibilities: Keep container tightly closed. Store in accordance with information listed on the product insert.
  • Requirements to be met by storerooms and receptacles: No special requirements.
  • Information about storage in one common storage facility: Not required.
  • Further information about storage conditions: None.
  • Specific end use(s): No further relevant information available.

8. Exposure controls/personal protection

  • Control parameters:
    • Components with limit values that require monitoring at the workplace: Not required.
    • Additional information: The lists that were valid during the creation were used as a basis.
  • Exposure controls:
    • Appropriate engineering controls: No further data; see Section 7.
  • Personal protective equipment:
    • General protective and hygienic measures: The usual precautionary measures for handling chemicals should be followed.
    • Breathing equipment: Not required.
    • Protection of hands: The glove material has to be impermeable and resistant to the product/the substance/the preparation. Due to missing tests, no recommendation to the glove material can be given. Selection of the glove material should consider penetration times, rates of diffusion, and degradation.
    • Material of gloves: The selection of suitable gloves depends not only on the material but also on further marks of quality and varies from manufacturer to manufacturer.
    • Penetration time of glove material: The exact break-through time has to be determined by the manufacturer of the protective gloves and must be observed.
    • Eye protection: Not required.

9. Physical and chemical properties

  • Physical state: powder
  • Color: Not determined.
  • Odor: Characteristic
  • Structural Formula: C25H22N6
  • Molecular Weight: 406.5 g/mol
  • Storage Buffer: No specific data provided for this section.
  • Odor threshold: Not determined.
  • Formulation: No specific data provided for this section.
  • Melting point/Melting range: Undetermined.
  • Boiling point/Boiling range: Undetermined.
  • Flammability: Product is not flammable.
  • Explosion limits: Lower: Not determined; Upper: Not determined.
  • Flash point: Not applicable.
  • Decomposition temperature: Not determined.
  • pH-value: Not applicable.
  • Viscosity: Kinematic: Not applicable; Dynamic: Not applicable.
  • Solubility: Chloroform: Slightly Soluble; DMSO: Slightly Soluble.
  • Solubility in / Miscibility with Water: Not determined.
  • Partition coefficient (n-octanol/water): Not determined.
  • Vapor pressure: Not applicable.
  • Density: Not determined.
  • Relative density: Not determined.
  • Vapor density: Not applicable.
  • Particle characteristics: Not determined.
  • Appearance (Form): powder
  • Ignition temperature: Not determined.
  • Danger of explosion: Product does not present an explosion hazard.
  • Evaporation rate: Not applicable.

10. Stability and reactivity

  • Reactivity: No further relevant information available.
  • Chemical stability:
    • Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
  • Possibility of hazardous reactions: No dangerous reactions known.
  • Conditions to avoid: No further relevant information available.
  • Incompatible materials: Strong acids, strong bases, strong oxidizing agents, strong reducing agents.
  • Hazardous decomposition products: No dangerous decomposition products known.

11. Toxicological information

  • Acute toxicity: No data provided.
  • Primary irritant effect:
    • On the skin: No irritant effect.
    • On the eye: No irritating effect.
  • Sensitization: No sensitizing effects known.
  • Additional toxicological information: When used and handled according to specifications, the product does not have any harmful effects according to experience and the information provided. The substance is not subject to classification.
  • Interactive effects: No interactive effects between components are known.
  • Carcinogenic categories:
    • IARC (International Agency for Research on Cancer): Substance is not listed.
    • NTP (National Toxicology Program): Substance is not listed.
    • OSHA-Ca (Occupational Safety & Health Administration): Substance is not listed.
  • Alternative sources for toxicological information: No non-standard sources for toxicological information were used.

12. Ecological information

  • Toxicity:
    • Aquatic toxicity: No further relevant information available.
  • Persistence and degradability: No further relevant information available.
  • Bioaccumulative potential: No further relevant information available.
  • Mobility in soil: No further relevant information available.
  • Results of PBT and vPvB assessment: PBT: Not applicable; vPvB: Not applicable.
  • Other adverse effects: No specific data provided for this section.
  • Additional ecological information:
    • General notes: Water hazard class 1 (Self-assessment): slightly hazardous for water. Do not allow undiluted product or large quantities of it to reach ground water, water course, or sewage system.

13. Disposal considerations

  • Waste treatment methods:
    • Recommendation: Smaller quantities can be disposed of with household waste.
  • Uncleaned packagings:
    • Recommendation: Disposal must be made according to official regulations.

14. Transport information

  • UN-Number (DOT, IMDG, IATA): Not regulated.
  • UN proper shipping name (DOT, IMDG, IATA): Not regulated.
  • Transport hazard class(es) (DOT, ADN, IMDG, IATA): Not regulated.
  • Packing group (DOT, IMDG, IATA): Not regulated.
  • Environmental hazards: Not applicable.
  • Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code: Not applicable.
  • Special precautions for user: Not applicable.
  • UN "Model Regulation": Not regulated.

15. Regulatory information

  • Safety, health and environmental regulations/legislation specific for the substance or mixture
  • No further relevant information available.
  • Sara
  • Section 355 (extremely hazardous substances):Substance is not listed.
  • Section 313 (Specific toxic chemical listings):Substance is not listed.
  • TSCA (Toxic Substances Control Act):Substance is not listed.
  • Hazardous Air PollutantsSubstance is not listed.
  • Chemicals known to cause cancer:Substance is not listed.
  • Chemicals known to cause reproductive toxicity for females:Substance is not listed.
  • Chemicals known to cause reproductive toxicity for males:Substance is not listed.
  • Chemicals known to cause developmental toxicity:Substance is not listed.
  • Carcinogenic categories
  • EPA (Environmental Protection Agency)Substance is not listed.
  • TLV (Threshold Limit Value)Substance is not listed.
  • NIOSH-Ca (National Institute for Occupational Safety and Health)Substance is not listed.
  • Chemical safety assessment:A Chemical Safety Assessment has not been carried out.

16. OTHER INFORMATION

Revision Date: 2026/06/30
Further Information: The information provided is believed to be correct but is not exhaustive and should be used only as a guideline based on current knowledge. It does not represent a guarantee of the properties of the product. Selleck Chemicals Corporation and its Affiliates shall not be held liable for any damage resulting from handling or contact with the product.