1.PRODUCT AND COMPANY IDENTIFICATION
Product identifier
- Product Name: LDN-193189
- Catalog Number: S2618
- CAS Number: 1062368-24-4
- IUPAC Name: 4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline
Relevant identified uses and uses advised against
- Identified uses: For research and development use only; laboratory chemicals; manufacture of substances.
- Uses advised against: Not for pharmaceutical, household, or other unapproved uses.
Details of the supplier
- Company : Selleck Chemicals
- TollFree : +1 877 796-6397
- Tel : +1 832 582-8158
- Fax : +1 832 582-8590
Emergency telephone number
- Emergency phone #: +1 832 582-8158
2. Hazard(s) identification
- Classification of the substance or mixture: The substance is not classified according to the Globally Harmonized System (GHS).
- Label elements:
- GHS label elements: None
- Hazard pictograms: None
- Signal word: None
- Hazard statements: None
- Information pertaining to particular dangers for man and environment: No specific data provided for this section.
- Classification system:
- NFPA ratings (scale 0 - 4): Health = 0, Fire = 0, Reactivity = 0.
- HMIS-ratings (scale 0 - 4): Health = 0, Fire = 0, Reactivity = 0.
- Other hazards:
- Results of PBT and vPvB assessment: PBT: Not applicable; vPvB: Not applicable.
- Classification according to (d)(1)(ii) of § 1910.1200: The SDS issuer does not object to the classifications provided by importers or manufacturers of precursor products.
- Hazards not otherwise classified: There are no adverse physical or health effects known that are not covered by the hazard classes of the Hazard Communications Standard.
3. Composition/information on ingredients
- Chemical characterization: Substances
- CAS No. Description: 1062368-24-4 LDN-193189
4. First-aid measures
- Description of first aid measures:
- General information: No special measures required.
- After inhalation: Supply fresh air; consult a doctor in case of complaints.
- After skin contact: Generally the product does not irritate the skin.
- After eye contact: Rinse opened eye for several minutes under running water.
- After swallowing: If symptoms persist, consult a doctor.
- Most important symptoms and effects, both acute and delayed: No further relevant information available.
- Indication of any immediate medical attention and special treatment needed: No further relevant information available.
5. Fire-fighting measures
- Extinguishing media:
- Suitable extinguishing agents: Use fire-fighting measures that suit the environment. A solid water stream may be inefficient.
- Special hazards arising from the substance or mixture: No further relevant information available.
- Advice for firefighters:
- Protective equipment: No special measures required.
6. Accidental release measures
- Personal precautions, protective equipment and emergency procedures: Not required.
- Environmental precautions: Do not allow to enter sewers, surface, or ground water.
- Methods and material for containment and cleaning up: Pick up mechanically.
- Protective Action Criteria for Chemicals:
- PAC-1: Substance is not listed.
- PAC-2: Substance is not listed.
- PAC-3: Substance is not listed.
- Reference to other sections: See Section 7 for information on safe handling, Section 8 for information on personal protection equipment, and Section 13 for disposal information.
7. Handling and storage
- Precautions for safe handling: No special measures required.
- Information about protection against explosions and fires: No special measures required.
- Conditions for safe storage, including any incompatibilities: Keep container tightly closed. Store in accordance with information listed on the product insert.
- Requirements to be met by storerooms and receptacles: No special requirements.
- Information about storage in one common storage facility: Not required.
- Further information about storage conditions: None.
- Specific end use(s): No further relevant information available.
8. Exposure controls/personal protection
- Control parameters:
- Components with limit values that require monitoring at the workplace: Not required.
- Additional information: The lists that were valid during the creation were used as a basis.
- Exposure controls:
- Appropriate engineering controls: No further data; see Section 7.
- Personal protective equipment:
- General protective and hygienic measures: The usual precautionary measures for handling chemicals should be followed.
- Breathing equipment: Not required.
- Protection of hands: The glove material has to be impermeable and resistant to the product/the substance/the preparation. Due to missing tests, no recommendation to the glove material can be given. Selection of the glove material should consider penetration times, rates of diffusion, and degradation.
- Material of gloves: The selection of suitable gloves depends not only on the material but also on further marks of quality and varies from manufacturer to manufacturer.
- Penetration time of glove material: The exact break-through time has to be determined by the manufacturer of the protective gloves and must be observed.
- Eye protection: Not required.
9. Physical and chemical properties
- Physical state: powder
- Color: Not determined.
- Odor: Characteristic
- Structural Formula: C25H22N6
- Molecular Weight: 406.5 g/mol
- Storage Buffer: No specific data provided for this section.
- Odor threshold: Not determined.
- Formulation: No specific data provided for this section.
- Melting point/Melting range: Undetermined.
- Boiling point/Boiling range: Undetermined.
- Flammability: Product is not flammable.
- Explosion limits: Lower: Not determined; Upper: Not determined.
- Flash point: Not applicable.
- Decomposition temperature: Not determined.
- pH-value: Not applicable.
- Viscosity: Kinematic: Not applicable; Dynamic: Not applicable.
- Solubility: Chloroform: Slightly Soluble; DMSO: Slightly Soluble.
- Solubility in / Miscibility with Water: Not determined.
- Partition coefficient (n-octanol/water): Not determined.
- Vapor pressure: Not applicable.
- Density: Not determined.
- Relative density: Not determined.
- Vapor density: Not applicable.
- Particle characteristics: Not determined.
- Appearance (Form): powder
- Ignition temperature: Not determined.
- Danger of explosion: Product does not present an explosion hazard.
- Evaporation rate: Not applicable.
10. Stability and reactivity
- Reactivity: No further relevant information available.
- Chemical stability:
- Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
- Possibility of hazardous reactions: No dangerous reactions known.
- Conditions to avoid: No further relevant information available.
- Incompatible materials: Strong acids, strong bases, strong oxidizing agents, strong reducing agents.
- Hazardous decomposition products: No dangerous decomposition products known.
11. Toxicological information
- Acute toxicity: No data provided.
- Primary irritant effect:
- On the skin: No irritant effect.
- On the eye: No irritating effect.
- Sensitization: No sensitizing effects known.
- Additional toxicological information: When used and handled according to specifications, the product does not have any harmful effects according to experience and the information provided. The substance is not subject to classification.
- Interactive effects: No interactive effects between components are known.
- Carcinogenic categories:
- IARC (International Agency for Research on Cancer): Substance is not listed.
- NTP (National Toxicology Program): Substance is not listed.
- OSHA-Ca (Occupational Safety & Health Administration): Substance is not listed.
- Alternative sources for toxicological information: No non-standard sources for toxicological information were used.
12. Ecological information
- Toxicity:
- Aquatic toxicity: No further relevant information available.
- Persistence and degradability: No further relevant information available.
- Bioaccumulative potential: No further relevant information available.
- Mobility in soil: No further relevant information available.
- Results of PBT and vPvB assessment: PBT: Not applicable; vPvB: Not applicable.
- Other adverse effects: No specific data provided for this section.
- Additional ecological information:
- General notes: Water hazard class 1 (Self-assessment): slightly hazardous for water. Do not allow undiluted product or large quantities of it to reach ground water, water course, or sewage system.
13. Disposal considerations
- Waste treatment methods:
- Recommendation: Smaller quantities can be disposed of with household waste.
- Uncleaned packagings:
- Recommendation: Disposal must be made according to official regulations.
14. Transport information
- UN-Number (DOT, IMDG, IATA): Not regulated.
- UN proper shipping name (DOT, IMDG, IATA): Not regulated.
- Transport hazard class(es) (DOT, ADN, IMDG, IATA): Not regulated.
- Packing group (DOT, IMDG, IATA): Not regulated.
- Environmental hazards: Not applicable.
- Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code: Not applicable.
- Special precautions for user: Not applicable.
- UN "Model Regulation": Not regulated.
15. Regulatory information
- Safety, health and environmental regulations/legislation specific for the substance or mixture
- No further relevant information available.
- Sara
- Section 355 (extremely hazardous substances):Substance is not listed.
- Section 313 (Specific toxic chemical listings):Substance is not listed.
- TSCA (Toxic Substances Control Act):Substance is not listed.
- Hazardous Air PollutantsSubstance is not listed.
- Chemicals known to cause cancer:Substance is not listed.
- Chemicals known to cause reproductive toxicity for females:Substance is not listed.
- Chemicals known to cause reproductive toxicity for males:Substance is not listed.
- Chemicals known to cause developmental toxicity:Substance is not listed.
- Carcinogenic categories
- EPA (Environmental Protection Agency)Substance is not listed.
- TLV (Threshold Limit Value)Substance is not listed.
- NIOSH-Ca (National Institute for Occupational Safety and Health)Substance is not listed.
- Chemical safety assessment:A Chemical Safety Assessment has not been carried out.
16. OTHER INFORMATION
Revision Date: 2026/06/30
Further Information: The information provided is believed to be correct but is not exhaustive and should be used only as a guideline based on current knowledge. It does not represent a guarantee of the properties of the product. Selleck Chemicals Corporation and its Affiliates shall not be held liable for any damage resulting from handling or contact with the product.