JQ-EZ-05 (JQEZ5) Chemical Structure (2D and 3D)

2D Structure

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2D chemical structural formula diagram.

3D Structure

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This 3D model represents a theoretically simulated conformation and is for reference only.

Check the JQ-EZ-05 (JQEZ5) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name	N-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-6-[6-(4-methylpiperazin-1-yl)-3-pyridinyl]-1-propan-2-ylpyrazolo[5,4-b]pyridine-4-carboxamide
CAS Number	1913252-04-6
Molecular Formula	C₃₀H₃₈N₈O₂
Molecular Weight (MW)	542.68
SMILES	CCCC1=C(C(=O)NC(=C1)C)CNC(=O)C2=CC(=NC3=C2C=NN3C(C)C)C4=CN=C(C=C4)N5CCN(CC5)C
InChIKey	LQTWDAYNGMMHLV-UHFFFAOYSA-N

Concentration Volume Mass

Batch:

All in vitro solubility values are batch-tested experimental data (non-literature values).

Solvent	Solubility & Note
DMSO	6 mg/mL (11.05 mM) (Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol	6 mg/mL
Water	Insoluble
DMSO	3 mg/mL (5.52 mM) (Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol	2 mg/mL
Water	Insoluble
DMSO	24 mg/mL (44.22 mM) (Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol	6 mg/mL
Water	Insoluble
DMSO	33 mg/mL (60.8 mM) (Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol	3 mg/mL
Water	Insoluble

FAQ

Q: Why does a DMSO stock precipitate in media/saline?

A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.

How to fix it?