LNP023 (Iptacopan) Hydrochloride: Mechanism of Action

LNP023 (Iptacopan) Hydrochloride MOA:Targeting Factor B/Alternative Complement Pathway for Paroxysmal Nocturnal Hemoglobinuria

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LNP023 (Iptacopan) Hydrochloride is a potent, highly selective Factor B inhibitor. It affects alternative complement pathway signaling by binding to the catalytically active site of Factor B, effectively inhibiting membrane attack complex formation and preventing complement activation.

Primary Applications and Mechanism of Action