Cell-free Assays (IC50/Ki) for LNP023 (Iptacopan) Hydrochloride
| Key Target | IC50 (Cell-free) | Description | Reference |
|---|---|---|---|
| Factor B (FB), AP-induced membrane attack complex formation | 0.01 ± 0.006 mM (for FB binding); 0.13 ± 0.06 mM (for MAC fo | Binding assay, Inhibition assay | PMC10166738 |
| Factor B (FB), AP-induced membrane attack complex formation | 0.01 ± 0.006 mM (for FB binding); 0.13 ± 0.06 mM (for MAC fo | Binding assay, Inhibition assay | PMC10166738 |
| Factor B (FB), AP-induced membrane attack complex formation | 0.01 ± 0.006 mM (for FB binding); 0.13 ± 0.06 mM (for MAC fo | Binding assay, Inhibition assay | PMC10166738 |
| Factor B (FB), AP-induced membrane attack complex formation | 0.01 ± 0.006 mM (for FB binding); 0.13 ± 0.06 mM (for MAC fo | Binding assay, Inhibition assay | PMC10166738 |
Cell-based Assay (IC50) for LNP023 (Iptacopan) Hydrochloride
| Cell Type | IC50 (Cell-based) | Description | Reference |
|---|---|---|---|
| No published data available. | |||
Check the
LNP023 (Iptacopan) Hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
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