Ipatasertib (GDC-0068): Mechanism of Action

Ipatasertib (GDC-0068) MOA:Targeting AKT/PI3K-AKT Pathway for Breast Cancer

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Ipatasertib (GDC-0068) is a potent, ATP-competitive AKT inhibitor. It affects PI3K/AKT/mTOR signaling pathways by binding to the AKT ATP-binding pocket, effectively inhibiting tumor cell proliferation, migration, and invasion, and promoting apoptosis.

Primary Applications and Mechanism of Action