2D Structure
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2D chemical structural formula diagram.
3D Structure
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This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
Ipatasertib (GDC-0068)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2S)-2-(4-chlorophenyl)-1-[4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl]-3-(propan-2-ylamino)propan-1-one | |
|---|---|---|
| CAS Number | 1001264-89-6 | |
| Molecular Formula |
C24H32ClN5O2 |
|
| Molecular Weight (MW) | 458 | |
| SMILES | CC1CC(C2=C1C(=NC=N2)N3CCN(CC3)C(=O)C(CNC(C)C)C4=CC=C(C=C4)Cl)O | |
| InChIKey | GRZXWCHAXNAUHY-NSISKUIASA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
91 mg/mL
(198.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 91 mg/mL |
| Water | Insoluble |
| DMSO |
92 mg/mL
(200.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 92 mg/mL |
| Water | 10 mg/mL |
| DMSO |
92 mg/mL
(200.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 92 mg/mL |
| Water | Insoluble |
| DMSO |
92 mg/mL
(200.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 92 mg/mL |
| Water | Insoluble |
| DMSO |
92 mg/mL
(200.87 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 92 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Ipatasertib (GDC-0068) Mechanism of Action: AKT Inhibition in Breast Cancer Cell Research
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- Ipatasertib (GDC-0068) Working Concentration | Cell Culture | Treatment
- Ipatasertib (GDC-0068) Solubility in DMSO
- Ipatasertib (GDC-0068) Stock Solution
- Ipatasertib (GDC-0068) Storage
- Ipatasertib (GDC-0068) Stability
- Ipatasertib (GDC-0068) Combination Database
- Ipatasertib (GDC-0068) Molecular Weight
- Ipatasertib (GDC-0068) SMILES
- Ipatasertib (GDC-0068) CAS Number
- Ipatasertib (GDC-0068) IC50 for Cell-based and Cell-free Assays
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- Ipatasertib (GDC-0068) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.