Hydroxyurea is a reversible RNR inhibitor. It affects p53 and mTOR pathways by depleting dNTP pools, inhibiting DNA synthesis.
Comprehensive IC50 Values for Hydroxyurea Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
Hydroxyurea is a reversible RNR inhibitor. It affects p53 and mTOR pathways by depleting dNTP pools, inhibiting DNA synthesis.