CAS No. 118-56-9

Batch: Purity:
Homosalate Chemical Structure
Chemical Structure
Check the Homosalate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 118-56-9
Molecular Formula

C16H22O3
Molecular Weight (MW) 262.34
SMILES CC1CC(CC(C)(C)C1)OC(=O)C2=C(O)C=CC=C2

Biological Activity

Homosalate is an organic ultraviolet filter widely used in sunscreen formulations that exhibits biological toxicity in marine organisms and human cell models. In human trophoblast cells, homosalate promotes cell invasion and regulates intracellular signal transduction by modulating the PI3K/AKT and MAPK pathways. These molecular alterations impact downstream cell motility and invasion phenotypes associated with placental development.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.