Guadecitabine sodium is a potent DNA methyltransferase (DNMT) inhibitor. It affects IFN and cGAS-STING signaling pathways by inducing DNA hypomethylation, effectively promoting tumor immunogenicity, MHC antigen presentation, and inhibiting tumor proliferation.
Guadecitabine sodium IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Guadecitabine sodium Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
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