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GSK126 SDS | MSDS

1.PRODUCT AND COMPANY IDENTIFICATION

Product identifier

  • Product Name: GSK126
  • Catalog Number: S7061
  • CAS Number: 1346574-57-9
  • IUPAC Name: 1-(S)-sec-butyl-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide

Relevant identified uses and uses advised against

  • Identified uses: For research and development use only; laboratory chemicals; manufacture of substances.
  • Uses advised against: Not for pharmaceutical, household, or other unapproved uses.

Details of the supplier

  • Company : Selleck Chemicals
  • TollFree : +1 877 796-6397
  • Tel : +1 832 582-8158
  • Fax : +1 832 582-8590

Emergency telephone number

  • Emergency phone #: +1 832 582-8158

2. Hazard(s) identification

The substance is not classified as hazardous according to the Globally Harmonized System (GHS).

  • GHS label elements: None
  • Hazard pictograms: None
  • Signal word: None
  • Hazard statements: None
  • NFPA ratings (scale 0 - 4): Health = 0, Fire = 0, Reactivity = 0.
  • HMIS-ratings (scale 0 - 4): Health = 0, Fire = 0, Physical Hazard = 0.
  • Other hazards: Results of PBT and vPvB assessment are not applicable. There are no known adverse physical or health effects.

3. Composition/information on ingredients

  • Chemical characterization: Substances
  • CAS No. Description: 1346574-57-9
  • Substance Name: 1-(S)-sec-butyl-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamide

4. First-aid measures

  • General information: No special measures required.
  • After inhalation: Supply fresh air; consult a doctor in case of complaints.
  • After skin contact: Generally, the product does not irritate the skin.
  • After eye contact: Rinse opened eye for several minutes under running water.
  • After swallowing: If symptoms persist, consult a doctor.
  • Most important symptoms and effects, both acute and delayed: No further relevant information available.
  • Indication of any immediate medical attention and special treatment needed: No further relevant information available.

5. Fire-fighting measures

  • Extinguishing media: Use fire-fighting measures that suit the environment. A solid water stream may be inefficient.
  • Special hazards arising from the substance or mixture: No further relevant information available.
  • Advice for firefighters: No special protective equipment required beyond standard measures.

6. Accidental release measures

  • Personal precautions, protective equipment and emergency procedures: Not required.
  • Environmental precautions: Do not allow to enter sewers, surface, or ground water.
  • Methods and material for containment and cleaning up: Pick up mechanically.
  • Reference to other sections: See Section 7 for safe handling, Section 8 for personal protection equipment, and Section 13 for disposal information.
  • Protective Action Criteria for Chemicals (PAC): Substance is not listed for PAC-1, PAC-2, or PAC-3.

7. Handling and storage

  • Precautions for safe handling: No special measures required.
  • Information about protection against explosions and fires: No special measures required.
  • Conditions for safe storage, including any incompatibilities: Store in accordance with information listed on the product insert. No special requirements for storerooms and receptacles.
  • Specific end use(s): No further relevant information available.

8. Exposure controls/personal protection

  • Control parameters: Components with limit values that require monitoring at the workplace are not required.
  • Appropriate engineering controls: No further data; see section 7.
  • Personal protective equipment:
    • General protective and hygienic measures: Follow usual precautionary measures for handling chemicals.
    • Breathing equipment: Not required.
    • Protection of hands: Use impermeable and resistant gloves. Due to missing tests, no specific glove material recommendation can be provided.
    • Eye protection: Not required.

9. Physical and chemical properties

  • Physical state: powder
  • Color: Not determined.
  • Odor: Characteristic
  • Structural Formula: C31H38N6O2
  • Molecular Weight: 526.7 g/mol
  • Melting point/Melting range: Undetermined.
  • Boiling point/Boiling range: Undetermined.
  • Flammability: Product is not flammable.
  • Flash point: Not applicable.
  • Decomposition temperature: Not determined.
  • Danger of explosion: Product does not present an explosion hazard.
  • Solubility: DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 15 mg/ml; Ethanol: 2 mg/ml.
  • Solubility in Water: Not determined.
  • Partition coefficient (n-octanol/water): Not determined.
  • Vapor pressure: Not applicable.
  • Density: Not determined.
  • Appearance Form: powder

10. Stability and reactivity

  • Reactivity: No further relevant information available.
  • Chemical stability: Stable if used according to specifications.
  • Possibility of hazardous reactions: No dangerous reactions known.
  • Conditions to avoid: No further relevant information available.
  • Incompatible materials: Strong oxidizing agents.
  • Hazardous decomposition products: Carbon dioxide, carbon monoxide, nitrogen oxides.

11. Toxicological information

  • Acute toxicity: No specific data provided.
  • Primary irritant effect:
    • On the skin: No irritant effect.
    • On the eye: No irritating effect.
  • Sensitization: No sensitizing effects known.
  • Additional toxicological information: The substance is not subject to classification. When handled according to specifications, the product does not have any harmful effects based on experience and available information.
  • Carcinogenic categories:
    • IARC: Substance is not listed.
    • NTP: Substance is not listed.
    • OSHA-Ca: Substance is not listed.

12. Ecological information

  • Toxicity: No further relevant information available.
  • Persistence and degradability: No further relevant information available.
  • Bioaccumulative potential: No further relevant information available.
  • Mobility in soil: No further relevant information available.
  • General notes: Water hazard class 1 (Self-assessment): slightly hazardous for water. Do not allow undiluted product or large quantities to reach ground water, water courses, or sewage systems.
  • Results of PBT and vPvB assessment: Not applicable.

13. Disposal considerations

  • Waste treatment methods: Smaller quantities can be disposed of with household waste.
  • Uncleaned packagings: Disposal must be made according to official regulations.

14. Transport information

  • UN-Number (DOT, IMDG, IATA): Not regulated.
  • UN proper shipping name (DOT, IMDG, IATA): Not regulated.
  • Transport hazard class(es) (DOT, ADN, IMDG, IATA): Not regulated.
  • Packing group (DOT, IMDG, IATA): Not regulated.
  • Environmental hazards: Not applicable.
  • Special precautions for user: Not applicable.
  • Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code: Not applicable.

15. Regulatory information

· Safety, health and environmental regulations/legislation specific for the substance or mixture
No further relevant information available.
· Sara
· Section 355 (extremely hazardous substances):Substance is not listed.
· Section 313 (Specific toxic chemical listings):Substance is not listed.
· TSCA (Toxic Substances Control Act):Substance is not listed.
· Hazardous Air PollutantsSubstance is not listed.
· Chemicals known to cause cancer:Substance is not listed.
· Chemicals known to cause reproductive toxicity for females:Substance is not listed.
· Chemicals known to cause reproductive toxicity for males:Substance is not listed.
· Chemicals known to cause developmental toxicity:Substance is not listed.
· Carcinogenic categories
· EPA (Environmental Protection Agency)Substance is not listed.
· TLV (Threshold Limit Value)Substance is not listed.
· NIOSH-Ca (National Institute for Occupational Safety and Health)Substance is not listed.
· Chemical safety assessment:A Chemical Safety Assessment has not been carried out.

16. OTHER INFORMATION

Revision Date: 2026/06/26
Further Information: The information provided is believed to be correct but is not exhaustive and should be used only as a guideline based on current knowledge. It does not represent a guarantee of the properties of the product. Selleck Chemicals Corporation and its Affiliates shall not be held liable for any damage resulting from handling or contact with the product.

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