Molecular Weight: 425.5 g/mol
Chemical Structure
Check the
GSK-1520489A
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
11 mg/mL
(25.85 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
| IUPAC Name | N-methyl-2-[[5-methyl-2-[3-(methylsulfonylmethyl)anilino]pyrimidin-4-yl]amino]benzamide | |
|---|---|---|
| CAS Number | 1042433-41-9 | |
| Molecular Formula |
C21H23N5O3S |
|
| Molecular Weight (MW) | 425.5 | |
| SMILES | CNC(=O)C1=CC=CC=C1NC2=NC(=NC=C2C)NC3=CC=CC(=C3)C[S](C)(=O)=O | |
| InChIKey | AKHLCKMEVWGDGL-UHFFFAOYSA-N |
Note: Technical data last updated: Sep 1, 2026.