Gemcitabine Hydrochloride is a potent RRM2 and DHFR inhibitor. It affects cGAS-STING and PI3K/Akt/mTOR pathways by incorporating into DNA and depleting nucleotides, inhibiting DNA synthesis and tumor proliferation.
Gemcitabine Hydrochloride IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Gemcitabine Hydrochloride Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.