SMILES:
COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4
Chemical Structure
Check the
Gefitinib (ZD1839)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine | |
|---|---|---|
| CAS Number | 184475-35-2 | |
| Molecular Formula |
C22H24ClFN4O3 |
|
| Molecular Weight (MW) | 446.90 | |
| SMILES | COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4 | |
| InChIKey | XGALLCVXEZPNRQ-UHFFFAOYSA-N |
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
89 mg/mL
(199.14 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 4 mg/mL |
| Water | Insoluble |
| DMSO |
89 mg/mL
(199.14 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 4 mg/mL |
| Water | Insoluble |
| DMSO |
89 mg/mL
(199.14 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 5 mg/mL |
| Water | Insoluble |
| DMSO |
45 mg/mL
(100.69 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 4 mg/mL |
| Water | Insoluble |
| DMSO |
89 mg/mL
(199.14 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 5 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Gefitinib (ZD1839) Mechanism of Action: EGFR Inhibition in Non-Small Cell Lung Cancer Cells Research
- Gefitinib (ZD1839) Clinical Trials
- Gefitinib (ZD1839): Selectivity & Specificity
- Gefitinib (ZD1839) Working Concentration | Cell Culture | Treatment
- Gefitinib (ZD1839) Solubility in DMSO
- Gefitinib (ZD1839) Stock Solution
- Gefitinib (ZD1839) Storage
- Gefitinib (ZD1839) Stability
- Gefitinib (ZD1839) Combination Database
- Gefitinib (ZD1839) Molecular Weight
- Gefitinib (ZD1839) CAS Number
- Gefitinib (ZD1839) Chemical Structure (2D and 3D)
- Gefitinib (ZD1839) IC50 for Cell-based and Cell-free Assays
- Gefitinib (ZD1839) Sigma (SML1657)? Try a better option.
- Gefitinib (ZD1839) MedChemExpress (HY-50895)? Try a better option.
- Gefitinib (ZD1839) APExBIO (A8219)? Try a better option.
- Gefitinib (ZD1839) Cayman (13166)? Try a better option.
- Gefitinib (ZD1839) Tocris (3000)? Try a better option.
- Gefitinib (ZD1839) SDS|MSDS
Note: Technical data last updated: Sep 1, 2026.