|
PC9
|
0.3724 µmol/L
|
MTT colorimetric assay
|
PMC12493104
|
|
PC9
|
0.1403 µmol/L
|
MTT colorimetric assay
|
PMC12493104
|
|
PC9/S100A6
|
1.126 µmol/L
|
MTT colorimetric assay
|
PMC12493104
|
|
PC9/S100A6
|
0.4998 µmol/L
|
MTT colorimetric assay
|
PMC12493104
|
|
H1975
|
> 10 µM
|
SRB assay, nonlinear regression analysis
|
PMC12997838
|
|
H1299
|
> 10 µM
|
SRB assay, nonlinear regression analysis
|
PMC12997838
|
|
PC9
|
0.013 µM
|
SRB assay, nonlinear regression analysis
|
PMC12997838
|
|
PC9-gef
|
2.39 µM
|
SRB assay, nonlinear regression analysis
|
PMC12997838
|
|
A549
|
8.18 µM
|
SRB assay, nonlinear regression analysis
|
PMC12997838
|
|
H1993
|
> 10 µM
|
SRB assay, nonlinear regression analysis
|
PMC12997838
|
|
H292
|
0.066 µM
|
SRB assay, nonlinear regression analysis
|
PMC12997838
|
|
H292-gef
|
15.13 µM
|
SRB assay, nonlinear regression analysis
|
PMC12997838
|
|
HCC827
|
0.012 µM
|
SRB assay, nonlinear regression analysis
|
PMC12997838
|
|
HCC827-gef
|
7.33 µM
|
SRB assay, nonlinear regression analysis
|
PMC12997838
|
|
CRLCs-CAFs-HUVECs (from patient LC-22)
|
13.62 µM
|
DST
|
PMC12261251
|
|
Ba/F3 EGFR Del19/T790M/C797S cells
|
> 10 μM
|
TR-FRET assays
|
PMC12135467
|
|
PC-9-PIK3CA-M
|
>10 μM
|
CCK-8 assay
|
PMC12902284
|
|
H1650
|
>10 μM
|
CCK-8 assay
|
PMC12902284
|
|
PC-9-MET-OE
|
>10 μM
|
CCK-8 assay
|
PMC12902284
|
|
Calu-3 cells
|
62 nM
|
MTT assay for cytotoxicity, Immunostaining assay for viral inhibition, 4-parameter non-linear regression curve fitting
|
Download PDF
|
|
OE21
|
0.06 µM
|
CellTitre-glo ®luminescent cell viability assay, GraphPad Prism non-linear regression analysis.
|
Download PDF
|
|
TE-8
|
0.08 µM
|
CellTitre-glo ®luminescent cell viability assay, GraphPad Prism non-linear regression analysis.
|
Download PDF
|
|
TE-15
|
0.17 µM
|
CellTitre-glo ®luminescent cell viability assay, GraphPad Prism non-linear regression analysis.
|
Download PDF
|
|
TE-11
|
0.19 µM
|
CellTitre-glo ®luminescent cell viability assay, GraphPad Prism non-linear regression analysis.
|
Download PDF
|
|
TE-14
|
0.23 µM
|
CellTitre-glo ®luminescent cell viability assay, GraphPad Prism non-linear regression analysis.
|
Download PDF
|
|
TE-6
|
0.29 µM
|
CellTitre-glo ®luminescent cell viability assay, GraphPad Prism non-linear regression analysis.
|
Download PDF
|
|
TE-9
|
0.61 µM
|
CellTitre-glo ®luminescent cell viability assay, GraphPad Prism non-linear regression analysis.
|
Download PDF
|
|
TE-4
|
0.67 µM
|
CellTitre-glo ®luminescent cell viability assay, GraphPad Prism non-linear regression analysis.
|
Download PDF
|
|
TE-5
|
0.68 µM
|
CellTitre-glo ®luminescent cell viability assay, GraphPad Prism non-linear regression analysis.
|
Download PDF
|
|
KYSE-410
|
0.74 µM
|
CellTitre-glo ®luminescent cell viability assay, GraphPad Prism non-linear regression analysis.
|
Download PDF
|
|
KYSE-520
|
1.31 µM
|
CellTitre-glo ®luminescent cell viability assay, GraphPad Prism non-linear regression analysis.
|
Download PDF
|
|
TE-10
|
2.52 µM
|
CellTitre-glo ®luminescent cell viability assay, GraphPad Prism non-linear regression analysis.
|
Download PDF
|
|
TE-1
|
22.81 µM
|
CellTitre-glo ®luminescent cell viability assay, GraphPad Prism non-linear regression analysis.
|
Download PDF
|
|
A549
|
21.84 µM
|
MTT assay
|
PMC11535926
|
|
NCI-H1975
|
13.1 µM
|
MTT assay
|
PMC11535926
|
|
A549, H1650, A549/GR, H1650/GR
|
A549: 7.53 µM; A549/GR: 15.40 µM; H1650: 25.38 µM; H1650/GR:
|
CCK-8 assay, relative survival curve
|
PMC11470737
|
|
A549 cells
|
9.97 µM
|
MTT assay
|
PMC11031755
|
|
HCC827 GR-High
|
>4 µM
|
tetrazolium-based (MTT) colorimetric assay
|
Download PDF
|
|
HCC827 GR-Low
|
>4 µM
|
tetrazolium-based (MTT) colorimetric assay
|
Download PDF
|
|
HCC827 GR-Pulse
|
>4 µM
|
tetrazolium-based (MTT) colorimetric assay
|
Download PDF
|
|
PC9 GR-High
|
>4 µM
|
tetrazolium-based (MTT) colorimetric assay
|
Download PDF
|
|
PC9 GR-Low
|
>4 µM
|
tetrazolium-based (MTT) colorimetric assay
|
Download PDF
|
|
PC9 GR-Pulse
|
>4 µM
|
tetrazolium-based (MTT) colorimetric assay
|
Download PDF
|
|
PC9
|
58 nM
|
MTT assay
|
PMC11704730
|
|
PC9/GR
|
17 μM
|
MTT assay
|
PMC11704730
|
|
HCC827
|
29 nM
|
MTT assay
|
PMC11704730
|
|
HCC827/GR
|
14 μM
|
MTT assay
|
PMC11704730
|
|
A549
|
3.34 μmol/L
|
CCK-8 assay
|
Download PDF
|
|
A549
|
21.3 μmol/L
|
CCK-8 assay
|
Download PDF
|
|
H1299
|
9.5 μmol/L
|
CCK-8 assay
|
Download PDF
|
|
PC9
|
0.17 μmol/L
|
CCK-8 assay
|
Download PDF
|
|
PC9GR
|
10.8 μmol/L
|
CCK-8 assay
|
Download PDF
|
|
MRC-5
|
3.6 μmol/L
|
CCK-8 assay
|
Download PDF
|
|
RA1
|
> 10 µM
|
MTT assays, Chou–Talalay method, CompuSyn software
|
Download PDF
|
|
RA2
|
> 10 µM
|
MTT assays, Chou–Talalay method, CompuSyn software
|
Download PDF
|
|
RB1
|
> 10 µM
|
MTT assays, Chou–Talalay method, CompuSyn software
|
Download PDF
|
|
PC-9
|
0.064 μM
|
Cell Counting Kit-8 (DOJINDO) cell viability assay, WST-8 reagent, Multiscan FC microplate reader at 450 nm
|
Download PDF
|
|
C4-2 cells in CSS-containing medium
|
0.33 μM
|
Cell proliferation assay (Cell Counting Kit-8)
|
Download PDF
|
|
C4-2 cells in FBS-containing medium
|
3.67 μM
|
Cell proliferation assay (Cell Counting Kit-8)
|
Download PDF
|
|
HCC827
|
1.65 µmol/L
|
Cell counting kit-8 (CCK-8) assay
|
PMC10230635
|
|
HepG2
|
4.69 µmol/L
|
Cell counting kit-8 (CCK-8) assay
|
PMC10230635
|
|
MCF7
|
3.95 µmol/L
|
Cell counting kit-8 (CCK-8) assay
|
PMC10230635
|
|
PC9
|
0.04 μM
|
CCK-8 assays
|
PMC10323565
|
|
PC9GR
|
7.43 μM
|
CCK-8 assays
|
PMC10323565
|
|
HCT116 wildtype
|
23.5 µM
|
Resazurin assay
|
Download PDF
|
|
HCT116 wildtype
|
23.5 µM
|
Resazurin assay
|
Download PDF
|
|
PC9 cells
|
15.99 nM
|
CCK8 assay
|
Download PDF
|
|
PC9/GR cells
|
4.427 µM
|
CCK8 assay
|
Download PDF
|
|
PC9/GR CTRL cells
|
4.118 µM
|
CCK8 assay
|
Download PDF
|
|
PC9/GR DCLK1-KO cells
|
1.924 µM
|
CCK8 assay
|
Download PDF
|
|
PC9/GR DCLK1 / CTRL cells
|
1.786 µM
|
CCK8 assay
|
Download PDF
|
|
PC9/GR DCLK1 / Res cells
|
3.577 µM
|
CCK8 assay
|
Download PDF
|
|
PC-9
|
8.87 µmol/L
|
CCK-8 kit
|
Download PDF
|
|
A549
|
9.19 µmol/L
|
CCK-8 kit
|
Download PDF
|
|
PC-9
|
143.70 µmol/L
|
CCK-8 kit
|
Download PDF
|
|
A549
|
93.14 µmol/L
|
CCK-8 kit
|
Download PDF
|
|
PC-9
|
6.98 µmol/L
|
CCK-8 kit
|
Download PDF
|
|
A549
|
11.13 µmol/L
|
CCK-8 kit
|
Download PDF
|
|
PC-9
|
5.74 µmol/L
|
CCK-8 kit
|
Download PDF
|
|
A549
|
9.81 µmol/L
|
CCK-8 kit
|
Download PDF
|
|
PC9
|
0.12 μmol/L
|
CCK-8 assay, curve regression analysis
|
Download PDF
|
|
PC9/BB4
|
11.41 μmol/L
|
CCK-8 assay, curve regression analysis
|
Download PDF
|
|
A549
|
14.39 μmol/L
|
CCK-8 assay, curve regression analysis
|
Download PDF
|
|
NCI-H1650
|
>20mM
|
MTT cytotoxicity assay
|
Download PDF
|
|
NCI-H1975
|
>20mM
|
MTT cytotoxicity assay
|
Download PDF
|
|
PC9
|
0.028 µM
|
CCK8 assay
|
Download PDF
|
|
PC9/R
|
8 µM
|
CCK8 assay
|
Download PDF
|
|
HCC827
|
0.141 µM
|
CCK8 assay
|
Download PDF
|
|
HCC/R
|
18.27 µM
|
CCK8 assay
|
Download PDF
|
|
PC9
|
0.47 μM
|
MTT assay
|
PMC9477152
|
|
PC9GR
|
35.30 μM
|
MTT assay
|
PMC9477152
|
|
SH-SY5Y
|
41.7 µM
|
MTT assay, CalcuSyn software
|
Download PDF
|
|
SK-N-BE(2)
|
86.7 µM
|
MTT assay, CalcuSyn software
|
Download PDF
|
|
SH-SY5Y
|
15.8 µM
|
MTT assay, CalcuSyn software
|
Download PDF
|
|
SK-N-BE(2)
|
20.0 µM
|
MTT assay, CalcuSyn software
|
Download PDF
|
|
DAOY
|
14.0 µM
|
MTT assay, CalcuSyn software
|
Download PDF
|
|
Saos-2
|
15.2 µM
|
MTT assay, CalcuSyn software
|
Download PDF
|
|
RD
|
15.5 µM
|
MTT assay, CalcuSyn software
|
Download PDF
|
|
PC9 cells
|
0.11 mM
|
MTT assay
|
PMC8474244
|
|
PC9-BrM3 cells
|
0.11 mM
|
MTT assay
|
PMC8474244
|
|
U87 (EGFRwt)
|
51.47 mM
|
MTT cell viability assays
|
Download PDF
|
|
U87 (EGFRmut)
|
215.0 mM
|
MTT cell viability assays
|
Download PDF
|
|
PriGBM (EGFRwt)
|
53.15 mM
|
MTT cell viability assays
|
Download PDF
|
|
PriGBM (EGFRmut)
|
432.9 mM
|
MTT cell viability assays
|
Download PDF
|
|
PC9
|
< 10 nM
|
Cell viability measured with Sulforhodamine B, IC50 calculated with SoftMax software.
|
Download PDF
|
|
HCC827
|
< 10 nM
|
Cell viability measured with Sulforhodamine B, IC50 calculated with SoftMax software.
|
Download PDF
|
|
HCC827/GR6
|
> 10,000 nM
|
Cell viability measured with Sulforhodamine B, IC50 calculated with SoftMax software.
|
Download PDF
|
|
H1975
|
> 10,000 nM
|
Cell viability measured with Sulforhodamine B, IC50 calculated with SoftMax software.
|
Download PDF
|
|
A549
|
> 10,000 nM
|
Cell viability measured with Sulforhodamine B, IC50 calculated with SoftMax software.
|
Download PDF
|
|
H460
|
> 10,000 nM
|
Cell viability measured with Sulforhodamine B, IC50 calculated with SoftMax software.
|
Download PDF
|
|
NCI-H1975 WT
|
0.75 μM
|
RealTime-Glo™ MT Cell Viability Assay Kit, nonlinear regression analysis (variable slope, 4-parameter)
|
Download PDF
|
|
NCI-H1975 GR
|
16.7 μM
|
RealTime-Glo™ MT Cell Viability Assay Kit, nonlinear regression analysis (variable slope, 4-parameter)
|
Download PDF
|
|
PC9
|
1.846 mM
|
CCK8 analysis
|
Download PDF
|
|
PC9-GR
|
3.512 mM
|
CCK8 analysis
|
Download PDF
|
|
PC9
|
0.32 mM
|
MTT assay
|
Download PDF
|
|
PC9-GR
|
3.45 mM
|
MTT assay
|
Download PDF
|
|
H292
|
0.51 mM
|
MTT assay
|
Download PDF
|
|
H292-GR
|
5.03 mM
|
MTT assay
|
Download PDF
|
|
LC124-O (EGFR-M)
|
0.413 µM
|
interpolation of dose-response curves using alamarBlueTM cell viability assay
|
Download PDF
|
|
LC100-O (EGFR-M)
|
0.241 µM
|
interpolation of dose-response curves using alamarBlueTM cell viability assay
|
Download PDF
|
|
LC101-O (EGFR-M)
|
0.393 µM
|
interpolation of dose-response curves using alamarBlueTM cell viability assay
|
Download PDF
|
|
LC126-O (EGFR-M)
|
0.651 µM
|
interpolation of dose-response curves using alamarBlueTM cell viability assay
|
Download PDF
|
|
LC131-O (EGFR-M)
|
0.272 µM
|
interpolation of dose-response curves using alamarBlueTM cell viability assay
|
Download PDF
|
|
LC133-O (EGFR-M)
|
0.624 µM
|
interpolation of dose-response curves using alamarBlueTM cell viability assay
|
Download PDF
|
|
H358 cells with EGFR L858R mutation
|
241.8 nM
|
Cell viability detected using Cell Counting Kit-8 reagent
|
PMC8350694
|
|
PC9
|
0.49 μM
|
CCK8 assay
|
Download PDF
|
|
PC9/GR
|
4.47 μM
|
CCK8 assay
|
Download PDF
|
|
DU145
|
11.88 µM
|
Growth inhibitory activity determined by crystal violet staining
|
Download PDF
|
|
Hep-G2
|
18.53 µM
|
Growth inhibitory activity determined by crystal violet staining
|
Download PDF
|
|
Jurkat
|
10.95 µM
|
Dual staining for Annexin-V and 7AAD via flow cytometry
|
Download PDF
|
|
Hut78
|
>20 µM
|
Dual staining for Annexin-V and 7AAD via flow cytometry
|
Download PDF
|
|
SupT11
|
>20 µM
|
Dual staining for Annexin-V and 7AAD via flow cytometry
|
Download PDF
|
|
SMZ1
|
>20 µM
|
Dual staining for Annexin-V and 7AAD via flow cytometry
|
Download PDF
|
|
H358
|
4.98 μM
|
CCK-8 assay
|
Download PDF
|
|
Calu-3
|
5.96 μM
|
CCK-8 assay
|
Download PDF
|
|
SNU-1327
|
19.3 μM
|
CCK-8 assay
|
Download PDF
|
|
H1703
|
21.13 μM
|
CCK-8 assay
|
Download PDF
|
|
HCC827
|
0.035 mM
|
MTT assay, non-linear regression model with a sigmoidal dose response using GraphPad Prism 8.0
|
Download PDF
|
|
H1650
|
1.27 mM
|
MTT assay, non-linear regression model with a sigmoidal dose response using GraphPad Prism 8.0
|
Download PDF
|
|
H1975
|
18.51 mM
|
MTT assay, non-linear regression model with a sigmoidal dose response using GraphPad Prism 8.0
|
Download PDF
|
|
HCC827-GR
|
3.22 mM
|
MTT assay, non-linear regression model with a sigmoidal dose response using GraphPad Prism 8.0
|
Download PDF
|
|
PC9-GR
|
15.16 μM
|
CCK8 assay
|
Download PDF
|
|
PC9
|
0.018 μM
|
CCK8 assay
|
Download PDF
|
|
143B
|
36.2 μM
|
CCK-8 assay
|
Download PDF
|
|
HOS
|
40 μM
|
CCK-8 assay
|
Download PDF
|
|
CAL-27
|
17.14 µM (24h), 2.00 µM (48h), 1.03 µM (72h)
|
MTT assay
|
Download PDF
|
|
SCC-25
|
36.15 µM (24h), 17.66 µM (48h), 8.64 µM (72h)
|
MTT assay
|
Download PDF
|
|
PC9R
|
9.82 μM
|
Cell Counting Kit-8 (CCK8) assay
|
PMC8044488
|
|
A549 cells
|
23.62 μmol/L
|
CCK-8 assay
|
Download PDF
|
|
H1299 cells
|
36.15 μmol/L
|
CCK-8 assay
|
Download PDF
|
|
HCC827 cells
|
2.906 μmol/L
|
CCK-8 assay
|
Download PDF
|
|
PC-9-Br
|
> 2.5 μM
|
MTT assays
|
Download PDF
|
|
PC-9-Br
|
0.1 μM
|
MTT assays
|
Download PDF
|
|
PC-9
|
0.75 μM
|
MTT assays
|
Download PDF
|
|
PC-9
|
0.027 μM
|
MTT assays
|
Download PDF
|
|
PC-9
|
32 nM
|
Cell proliferation measured using Cell Counting Kit-8 (CCK-8)
|
Download PDF
|
|
PC-9/GR
|
6.547 μM
|
Cell proliferation measured using Cell Counting Kit-8 (CCK-8)
|
Download PDF
|
|
A549
|
10.53 μM
|
MTT assay
|
PMC7947404
|
|
3LL
|
23.67 μM
|
MTT assay
|
PMC7947404
|
|
Ba/F3 (EGFR-L747P)
|
>1000 nM
|
assay
|
Download PDF
|
|
Ba/F3 (EGFR-L858R)
|
1.0 nM
|
assay
|
Download PDF
|
|
Ba/F3 (EGFR-del19)
|
1.0 nM
|
assay
|
Download PDF
|
|
Ba/F3 (EGFR-L858R/T790M)
|
>1000 nM
|
assay
|
Download PDF
|
|
Ba/F3 (EGFR-del19/T790M)
|
>1000 nM
|
assay
|
Download PDF
|
|
PC9/ER
|
22.3652 μM
|
CCK-8 assay
|
Download PDF
|
|
PC9 cells with shisa3 knockdown
|
0.07616 μM
|
CCK-8 assay
|
Download PDF
|
|
OE21
|
0.035 µM
|
CellTitre-Glo® luminescent cell viability assay, CalcuSyn or Graphpad prism software
|
Download PDF
|
|
TE8
|
0.23 µM
|
CellTitre-Glo® luminescent cell viability assay, CalcuSyn or Graphpad prism software
|
Download PDF
|
|
KYSE520
|
1.312 µM
|
CellTitre-Glo® luminescent cell viability assay, CalcuSyn or Graphpad prism software
|
Download PDF
|
|
HCC827 GR
|
> 10 μM
|
Cell Counting Kit-8 (CCK-8) assay
|
PMC7327692
|
|
PC-9 GR
|
> 10 μM
|
Cell Counting Kit-8 (CCK-8) assay
|
PMC7327692
|
|
A549 cells
|
6.343 μM
|
CellTiter96 Aqueous one solution Cell proliferation assay (MTS assay)
|
PMC6668247
|
|
Panc-1
|
25.57 μM
|
MTS colorimetric assay
|
PMC6935307
|
|
Miapaca-2
|
22.79 μM
|
MTS colorimetric assay
|
PMC6935307
|
|
HCC827/gefitinib
|
172.20 nM
|
CCK-8 assay
|
PMC6844214
|
|
PC-9/gefitinib
|
167.00 nM
|
CCK-8 assay
|
PMC6844214
|
|
HCC827GR
|
20 μmol/L
|
CCK-8 method
|
Download PDF
|
|
A549
|
18.90 μmol/L
|
CCK-8 assay, calculated using GraphPad Prism v. 7.0
|
Download PDF
|
|
H1975
|
16.40 μmol/L
|
CCK-8 assay, calculated using GraphPad Prism v. 7.0
|
Download PDF
|
|
PC9
|
1.794 μmol/L
|
CCK-8 assay, calculated using GraphPad Prism v. 7.0
|
Download PDF
|
|
PC9/GR
|
15.99 μmol/L
|
CCK-8 assay, calculated using GraphPad Prism v. 7.0
|
Download PDF
|
|
PC9/GR
|
18.716 μmol/L
|
CCK-8 assay, calculated using GraphPad Prism v. 7.0
|
Download PDF
|
|
HCC827
|
0.029 μmol/L
|
Cell counting kit-8 (CCK-8) assay
|
PMC7262931
|
|
H3255
|
0.18 μmol/L
|
Cell counting kit-8 (CCK-8) assay
|
PMC7262931
|
|
HeLa cells expressing EGFRL858R
|
<20 nM
|
Intracellular accumulation assay
|
PMC7276512
|
|
HeLa cells expressing EGFRE746_A750del
|
<20 nM
|
Intracellular accumulation assay
|
PMC7276512
|
|
HeLa cells expressing EGFRL747_E749del
|
156 nM
|
Intracellular accumulation assay
|
PMC7276512
|
|
HeLa cells expressing EGFRS768I
|
625 nM
|
Intracellular accumulation assay
|
PMC7276512
|
|
HeLa cells expressing EGFRG719S
|
456 nM
|
Intracellular accumulation assay
|
PMC7276512
|
|
HeLa cells expressing DL747_T751
|
156 nM
|
Intracellular accumulation assay
|
PMC7276512
|
|
HeLa cells expressing DE746_A750
|
2.4 nM
|
Intracellular accumulation assay
|
PMC7276512
|
|
HeLa cells expressing DE746_A750
|
2 nM
|
Intracellular accumulation assay
|
PMC7276512
|
|
HeLa cells expressing DL747_A750
|
2 nM
|
Intracellular accumulation assay
|
PMC7276512
|
|
HeLa cells expressing EGFRT751-I759delinsATA
|
40 nM
|
Intracellular accumulation assay
|
PMC7276512
|
|
A549
|
8.42 μmol/L
|
Crystal violet assay, curvilinear regression equation
|
Download PDF
|
|
H1650
|
5.26 μmol/L
|
Crystal violet assay, curvilinear regression equation
|
Download PDF
|
|
A549GSC
|
36.97 μmol/L
|
Crystal violet assay, curvilinear regression equation
|
Download PDF
|
|
H1650GSC
|
27.11 μmol/L
|
Crystal violet assay, curvilinear regression equation
|
Download PDF
|
|
A549
|
6 µM
|
MTT cell proliferation assay
|
PMC6186900
|
|
Calu1
|
11.93 µM
|
MTT cell proliferation assay
|
PMC6186900
|
|
H1650
|
8.79 µM
|
MTT cell proliferation assay
|
PMC6186900
|
|
H1975
|
10.312 μM
|
Cell Counting Kit-8 (CCK-8) assay
|
Download PDF
|
|
PC-9
|
0.009 μM
|
Cell Counting Kit-8 (CCK-8) assay
|
Download PDF
|
|
H1975
|
> 20 µM
|
MTT assay
|
PMC6124478
|
|
SGC7901
|
50 nM
|
MTT assay
|
Download PDF
|
|
SGC7901R
|
2 μM
|
MTT assay
|
Download PDF
|
|
H157
|
17.98 nM
|
MTT assay
|
PMC8641506
|
|
HSC-2
|
18.50 nM
|
MTT assay
|
PMC8641506
|
|
U251
|
105.1 μM
|
CCK-8 assay
|
Download PDF
|
|
U251
|
35.25 μM
|
CCK-8 assay
|
Download PDF
|
|
U87
|
35.88 μM
|
CCK-8 assay
|
Download PDF
|
|
U87
|
24.21 μM
|
CCK-8 assay
|
Download PDF
|
|
GBM1
|
54.35 μM
|
CCK-8 assay
|
Download PDF
|
|
GBM1
|
18.56 μM
|
CCK-8 assay
|
Download PDF
|
|
GBM2
|
27.98 μM
|
CCK-8 assay
|
Download PDF
|
|
GBM2
|
14.49 μM
|
CCK-8 assay
|
Download PDF
|
|
GBM3
|
21.82 μM
|
CCK-8 assay
|
Download PDF
|
|
GBM3
|
12.69 μM
|
CCK-8 assay
|
Download PDF
|
|
PC9
|
2.73 μmol/L
|
CCK-8 assay
|
Download PDF
|
|
PC9/AB2
|
30.27 μmol/L
|
CCK-8 assay
|
Download PDF
|
|
A549
|
21 μM
|
CCK-8 assay
|
Download PDF
|
|
H1573
|
18 μM
|
CCK-8 assay
|
Download PDF
|
|
A549 (SCD1 overexpressed)
|
42 μM
|
CCK-8 assay
|
Download PDF
|
|
H1573 (SCD1 overexpressed)
|
40 μM
|
CCK-8 assay
|
Download PDF
|
|
H1975 (NC)
|
9.41 μM
|
MTT assay
|
PMC6108345
|
|
H1975 (IGF-1R siRNA)
|
4 μM
|
MTT assay
|
PMC6108345
|
|
PC9 cells
|
< 20 nM
|
Cell counting kit-8 (CCK-8) analysis
|
PMC6166090
|
|
PC9 cells
|
0.74 μM
|
CCK-8 kit
|
PMC5928882
|
|
H1650 cells
|
16.9 μM
|
CCK-8 kit
|
PMC5928882
|
|
Cal27
|
0.15 μM
|
MTS assay
|
Download PDF
|
|
Cal27GR
|
15 μM
|
MTS assay
|
Download PDF
|
|
NCI-H1975
|
10 µM
|
CCK-8 assay
|
Download PDF
|
|
A549
|
10 µM
|
CCK-8 assay
|
Download PDF
|
|
HCC827
|
0.01 µM
|
CCK-8 assay
|
Download PDF
|
|
UM-SCC-4
|
2.51 μM
|
CellTiter-Glo®Luminescent Cell Viability Assay
|
Download PDF
|
|
UM-SCC-6
|
0.04 μM
|
CellTiter-Glo®Luminescent Cell Viability Assay
|
Download PDF
|
|
UM-SCC-10A
|
0.47 μM
|
CellTiter-Glo®Luminescent Cell Viability Assay
|
Download PDF
|
|
UM-SCC-18
|
0.0089 μM
|
CellTiter-Glo®Luminescent Cell Viability Assay
|
Download PDF
|
|
UM-SCC-19
|
0.98 μM
|
CellTiter-Glo®Luminescent Cell Viability Assay
|
Download PDF
|
|
UM-SCC-23
|
2.57 μM
|
CellTiter-Glo®Luminescent Cell Viability Assay
|
Download PDF
|
|
UM-SCC-47
|
8.43 μM
|
CellTiter-Glo®Luminescent Cell Viability Assay
|
Download PDF
|
|
UPCI:SCC-90
|
0.37 μM
|
CellTiter-Glo®Luminescent Cell Viability Assay
|
Download PDF
|
|
UM-SCC-104
|
0.058 μM
|
CellTiter-Glo®Luminescent Cell Viability Assay
|
Download PDF
|
|
UPCI:SCC-154
|
14.3 μM
|
CellTiter-Glo®Luminescent Cell Viability Assay
|
Download PDF
|
|
UD-SCC-2
|
6.96 μM
|
CellTiter-Glo®Luminescent Cell Viability Assay
|
Download PDF
|
|
93-VU147T
|
0.13 μM
|
CellTiter-Glo®Luminescent Cell Viability Assay
|
Download PDF
|
|
UM-SCC-4 (empty)
|
2.03 μM
|
CellTiter-Glo®Luminescent Cell Viability Assay
|
Download PDF
|
|
UM-SCC-4 (EGFR)
|
3.12 μM
|
CellTiter-Glo®Luminescent Cell Viability Assay
|
Download PDF
|
|
HCC827
|
1.6 nM
|
MTT assay
|
Download PDF
|
|
MB49
|
1.6 µmol/L
|
Tetrazolium-based assay (MTT assay)
|
Download PDF
|
|
T24
|
30.1 µmol/L
|
Tetrazolium-based assay (MTT assay)
|
Download PDF
|
|
UMUC3
|
17 µmol/L
|
Tetrazolium-based assay (MTT assay)
|
Download PDF
|
|
MCF 10A (Control)
|
0.180 µM
|
assay, luminescence measurement using an EnSpire plate reader, analyzed with Morphit software.
|
PMC5355725
|
|
MCF 10A (WT EGFR)
|
0.371 µM
|
assay, luminescence measurement using an EnSpire plate reader, analyzed with Morphit software.
|
PMC5355725
|
|
MCF 10A (L858R EGFR)
|
0.034 µM
|
assay, luminescence measurement using an EnSpire plate reader, analyzed with Morphit software.
|
PMC5355725
|
|
MCF 10A (T790M EGFR)
|
5.781 µM
|
assay, luminescence measurement using an EnSpire plate reader, analyzed with Morphit software.
|
PMC5355725
|
|
MCF 10A (Parental)
|
218 nM
|
assay, luminescence measurement using an EnSpire plate reader, analyzed with Morphit software.
|
PMC5355725
|
|
MCF 10A (L858R isogenic)
|
45 nM
|
assay, luminescence measurement using an EnSpire plate reader, analyzed with Morphit software.
|
PMC5355725
|
|
MCF 10A (T790M isogenic)
|
846 nM
|
assay, luminescence measurement using an EnSpire plate reader, analyzed with Morphit software.
|
PMC5355725
|
|
PC-9
|
0.05 μmol/L
|
MTT assay, 570 nm absorbance detection, linear regression
|
Download PDF
|
|
PC-9 ID1 OE
|
0.64 μmol/L
|
MTT assay, 570 nm absorbance detection, linear regression
|
Download PDF
|
|
PC-9R
|
5.05 μmol/L
|
MTT assay, 570 nm absorbance detection, linear regression
|
Download PDF
|
|
PC-9R ID1 siRNA
|
1.14 μmol/L
|
MTT assay, 570 nm absorbance detection, linear regression
|
Download PDF
|
|
CAL27
|
0.370 µM
|
CCK-8 assay, calculated using GraphPad Prism 7
|
PMC6250113
|
|
Detroit562
|
1.027 µM
|
CCK-8 assay, calculated using GraphPad Prism 7
|
PMC6250113
|
|
JHU011
|
0.929 µM
|
CCK-8 assay, calculated using GraphPad Prism 7
|
PMC6250113
|
|
HN4
|
0.576 µM
|
CCK-8 assay, calculated using GraphPad Prism 7
|
PMC6250113
|
|
HSC3
|
1.059 µM
|
CCK-8 assay, calculated using GraphPad Prism 7
|
PMC6250113
|
|
SCC4
|
0.926 µM
|
CCK-8 assay, calculated using GraphPad Prism 7
|
PMC6250113
|
|
MCF-7
|
21.2 μM
|
Cell proliferation determined by Incucyte® live cell analysis system, calculated through non-linear regression analysis using SigmaPlot ver. 12.
|
Download PDF
|
|
PC9
|
0.05 μM
|
MTT assay
|
PMC5925453
|
|
H1975
|
10.00 μM
|
MTT assay, Chou and Talalay method
|
PMC5925453
|
|
11-18
|
0.80 μM
|
Cell viability assay (MTT assay)
|
PMC5925453
|
|
HCC4006
|
0.03 μM
|
Cell viability assay (MTT assay)
|
PMC5925453
|
|
HCC827
|
0.02 μM
|
Cell viability assay (MTT assay)
|
PMC5925453
|
|
PC9
|
0.02 μM
|
WST-1 assay
|
Download PDF
|
|
HCC827
|
0.03 μM
|
WST-1 assay
|
Download PDF
|
|
H1975
|
1.2 μM
|
WST-1 assay
|
Download PDF
|
|
H1437
|
>10 μM
|
WST-1 assay
|
Download PDF
|
|
H1299
|
>10 μM
|
WST-1 assay
|
Download PDF
|
|
HN137-Pri
|
0.183 μM
|
luminescent cell viability reagent
|
Download PDF
|
|
HN137-Met
|
16.4 μM
|
luminescent cell viability reagent
|
Download PDF
|
|
HN137-Pri YAP1
|
>10 μM
|
luminescent cell viability reagent
|
Download PDF
|
|
HN137-Pri
|
0.124 μM
|
luminescent cell viability reagent
|
Download PDF
|
|
OVCAR-3
|
4.2 μM
|
colorimetric assay using SRB
|
Download PDF
|
|
IGROV-1
|
7.77 μM
|
colorimetric assay using SRB
|
Download PDF
|
|
A2780
|
5.2 μM
|
colorimetric assay using SRB
|
Download PDF
|
|
SKOV-3
|
72.66 μM
|
colorimetric assay using SRB
|
Download PDF
|
|
EFO-21
|
139.87 μM
|
colorimetric assay using SRB
|
Download PDF
|
|
Cal27
|
6 μM
|
alamarBlue assay
|
PMC5694417
|
|
OSC19
|
2.5 μM
|
alamarBlue assay
|
PMC5694417
|
|
SCC25
|
2.5 μM
|
alamarBlue assay
|
PMC5694417
|
|
H1975
|
22.61 µmol/L
|
3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method
|
PMC4321659
|
|
A549
|
12.8 µmol/L
|
3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide assay
|
PMC5108607
|
|
H1299
|
28.7 µmol/L
|
3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide assay
|
PMC5108607
|
|
H358
|
1.3 µmol/L
|
3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide assay
|
PMC5108607
|
|
H322
|
1.5 µmol/L
|
3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide assay
|
PMC5108607
|
|
H1719
|
6.0 µmol/L
|
3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide assay
|
PMC5108607
|
|
Hep3B
|
12.5 µmol/L
|
3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide assay
|
PMC5108607
|
|
Huh7
|
14.5 µmol/L
|
3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide assay
|
PMC5108607
|
|
HepG2
|
9.6 µmol/L
|
3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide assay
|
PMC5108607
|
|
PLC/PRF5
|
9.4 µmol/L
|
3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide assay
|
PMC5108607
|
|
H3255
|
40 nM
|
in vitro assay
|
Download PDF
|
|
DFCILU-011
|
40 nM
|
in vitro assay
|
Download PDF
|
|
MDA-MB-468, HCC-1395, MDA-MB-231, T47D
|
1-5 uM
|
MTS assay
|
PMC4216798
|
|
NCI-H460
|
8.8 uM
|
MTT assay
|
PMC5625681
|
|
HL-NG (0.1% FCS)
|
6.9 μM
|
MTT assay
|
Download PDF
|
|
MG-63 (0.1% FCS)
|
5.1 μM
|
MTT assay
|
Download PDF
|
|
HOS (0.1% FCS)
|
12.1 μM
|
MTT assay
|
Download PDF
|
|
Saos-2 (0.1% FCS)
|
13.8 μM
|
MTT assay
|
Download PDF
|
|
OS-10 (0.1% FCS)
|
6.0 μM
|
MTT assay
|
Download PDF
|
|
OS-9 (0.1% FCS)
|
7.3 μM
|
MTT assay
|
Download PDF
|
|
SARG (0.1% FCS)
|
3.6 μM
|
MTT assay
|
Download PDF
|
|
IOR-MOS (0.1% FCS)
|
2.8 μM
|
MTT assay
|
Download PDF
|
|
U-2 OS (0.1% FCS)
|
28.1 μM
|
MTT assay
|
Download PDF
|
|
DiFi
|
24.98 nM
|
sulphorodhamine B (SRB) colorimetric assay
|
PMC4651123
|
|
DiFi62
|
17.16 nM
|
sulphorodhamine B (SRB) colorimetric assay
|
PMC4651123
|
|
DiFiG
|
113.74 nM
|
sulphorodhamine B (SRB) colorimetric assay
|
PMC4651123
|
|
H292
|
0.166 μM
|
MTT assay
|
Download PDF
|
|
HCC827
|
0.015 μM
|
MTT assay
|
Download PDF
|
|
PC9/GRc
|
17.8 μM
|
CellTiter 96® AQueous One Solution Cell Proliferation Assay
|
Download PDF
|
|
PC9/GRi
|
15.8 μM
|
CellTiter 96® AQueous One Solution Cell Proliferation Assay
|
Download PDF
|
|
PC9/GRc
|
13.5 μM
|
MTS cell proliferation assay
|
Download PDF
|
|
PC9/GRi
|
1.04 μM
|
MTS cell proliferation assay
|
Download PDF
|
|
A549
|
1.22 x 10^-5 mol/L
|
MTT assay
|
Download PDF
|
|
PC-9
|
5.65 x 10^-8 mol/L
|
MTT assay
|
Download PDF
|
