Ferrostatin-1 (Fer-1): Selectivity & Specificity
Ferrostatin-1 (Fer-1) is a potent inhibitor of Liposomes (1660 nM), Ferroptosis, Lipid peroxidation, ROS, Labile iron pool, GPX4, NRF2, SLC7A11, PTGS2, IDO1, ACSL3, ALOX15, HSPB1, SLC11A2, GCLC, HMGB1, TLR4, NLRP3, NF-κB, MDA, GSH, RNS, TNF-α, IL-6. Ferrostatin-1 (Fer-1) exhibits the greatest inhibitory potency toward Liposomes (IC50 = 1660 nM).