Dinaciclib is a potent CDK inhibitor. It affects Rb signaling by reducing Rb phosphorylation, stopping growth, inducing apoptosis.
Comprehensive IC50 Values for Dinaciclib (SCH 727965) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
Dinaciclib is a potent CDK inhibitor. It affects Rb signaling by reducing Rb phosphorylation, stopping growth, inducing apoptosis.