CAS No. 78213-16-8
| IUPAC Name | 2-[2-(2,6-dichloroanilino)phenyl]acetic acid;N-ethylethanamine | |
|---|---|---|
| CAS Number | 78213-16-8 | |
| Molecular Formula |
C14H11Cl2NO2.C4H11N |
|
| Molecular Weight (MW) | 369.29 | |
| SMILES | CCNCC.C1=CC=C(C(=C1)CC(=O)O)NC2=C(C=CC=C2Cl)Cl | |
| InChIKey | ZQVZPANTCLRASL-UHFFFAOYSA-N |
Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug (NSAID) that acts as an inhibitor of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). By blocking COX enzymatic activity, it suppresses prostaglandin synthesis, leading to decreased inflammatory mediator production and attenuation of pain signaling pathways. This inhibition of the arachidonic acid cascade reduces downstream vascular permeability and leukocyte recruitment during inflammatory responses. [1]
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Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
74 mg/mL
(200.38 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 74 mg/mL |
| Water | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
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- Diclofenac Diethylamine Solubility in DMSO
- Diclofenac Diethylamine Stock Solution
- Diclofenac Diethylamine Storage
- Diclofenac Diethylamine Stability
- Diclofenac Diethylamine Molecular Weight
- Diclofenac Diethylamine SMILES
- Diclofenac Diethylamine Chemical Structure (2D and 3D)
- Diclofenac Diethylamine SDS｜MSDS