Deferasirox (ICL670) is a potent iron chelator. It affects PI3K/AKT/mTOR and STAT1 signaling pathways by binding to intracellular iron and depleting iron stores, effectively inhibiting cancer cell proliferation, stemness, and inducing apoptosis.
Comprehensive IC50 Values for Deferasirox (ICL670) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
Deferasirox (ICL670) is a potent iron chelator. It affects PI3K/AKT/mTOR and STAT1 signaling pathways by binding to intracellular iron and depleting iron stores, effectively inhibiting cancer cell proliferation, stemness, and inducing apoptosis.