Home Biosimilar Antibodies Others Antibody-Drug Conjugate inhibitor Datopotamab deruxtecan
For research use only. Not for use in humans.

Datopotamab deruxtecan

Synonyms: DS-1062, DS-1062A, Anti-TRP2/dxd

Datopotamab deruxtecan (DS-1062, DS-1062A, Anti-TRP2/dxd) is an antibody-drug conjugate (ADC) composed of a humanized anti-TROP2 monoclonal antibody, conjugated to topoisomerase I inhibitor, via a tetrapeptide-based linker. Datopotamab deruxtecan has the potential for use in solid tumors mainly in advanced unresectable advanced NSCLC.

Datopotamab deruxtecan

CAS No. 2238831-60-0

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Quality Control

Batch: Purity: 99% Protein concentration: 14.37mg/ml Endotoxin Level: ＜1EU/mg
99

Specificity

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Datopotamab deruxtecan (DS-1062, DS-1062A, Anti-TRP2/dxd) is an antibody-drug conjugate (ADC) composed of a humanized anti-TROP2 monoclonal antibody, conjugated to topoisomerase I inhibitor, via a tetrapeptide-based linker. Datopotamab deruxtecan has the potential for use in solid tumors mainly in advanced unresectable advanced NSCLC.
References

Product Details

CAS No. 2238831-60-0
DAR 4.2
ADC antiody Datopotamab
ADC linker A tetrapeptide-based linker
ADC cytotoxin Dxd
Formulation 100 mM Pro-Ac，20 mM Arg，pH 5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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