Cell-free Assays (IC50/Ki) for Daraxonrasib (RMC-6236)
| Key Target | IC50 (Cell-free) | Description | Reference |
|---|---|---|---|
| No published data available. | |||
Cell-based Assay (IC50) for Daraxonrasib (RMC-6236)
| Cell Type | IC50 (Cell-based) | Description | Reference |
|---|---|---|---|
| AAPDO-01 (KRASG12D organoids) | 4.43 nM | Organoid growth quantification (Organoid Object Total Area (µm²/Image) monitored with Incucyte SX5) | PMC13082064 |
| AAPDO-16 (KRASG12V organoids) | 0.5 nM | Organoid growth quantification (Organoid Object Total Area (µm²/Image) monitored with Incucyte SX5) | PMC13082064 |
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Daraxonrasib (RMC-6236)
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- Daraxonrasib (RMC-6236) Mechanism of Action: RAS Inhibition in Pancreatic Cancer Cell Research
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- Daraxonrasib (RMC-6236) Combination Database
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- Daraxonrasib (RMC-6236) SDS｜MSDS