Cell-free Assays (IC50/Ki) for Cytochalasin D
| Key Target | IC50 (Cell-free) | Description | Reference |
|---|---|---|---|
| No published data available. | |||
Cell-based Assay (IC50) for Cytochalasin D
| Cell Type | IC50 (Cell-based) | Description | Reference |
|---|---|---|---|
| P388/ADR | 42 μM | MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assays | Download PDF |
| L929 | 0.75 µM | half-maximal inhibitory concentration (IC50) was determined adopting the previously described method [ 23, 24]. | Download PDF |
| KB3.1 | 0.12 µM | half-maximal inhibitory concentration (IC50) was determined adopting the previously described method [ 23, 24]. | Download PDF |
| SKOV-3 | 0.10 µM | half-maximal inhibitory concentration (IC50) was determined adopting the previously described method [ 23, 24]. | Download PDF |
| A431 | 0.24 µM | half-maximal inhibitory concentration (IC50) was determined adopting the previously described method [ 23, 24]. | Download PDF |
| A549 | 0.57 µM | half-maximal inhibitory concentration (IC50) was determined adopting the previously described method [ 23, 24]. | Download PDF |
| L. (V.) braziliensis (amastigote forms) | 72.6 µM | Luciferase activity assay, calculated by sigmoidal regression analyses using GraphPad Prism. | Download PDF |
| THP-1 cells | > 200 µM | MTT assay, quantified using a spectrophotometer (absorbance at 570 nm). | Download PDF |
| Vero cells | > 200 µM | MTT assay, measuring mitochondrial reduction. | Download PDF |
| Colletotrichum gloeosporioides | 2.46 µmol/mL | Broth microdilution techniques, determined spectrophotometrically according to NCCLS guidelines | PMC6175768 |
Check the
Cytochalasin D
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
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