CAS No. 60-27-5
| CAS Number | 60-27-5 | |
|---|---|---|
| Molecular Formula |
C4H7N3O |
|
| Molecular Weight (MW) | 113.12 | |
| SMILES | CN1CC(=O)N=C1N |
Creatinine is an endogenous metabolite and breakdown product derived non-enzymatically from creatine phosphate in muscle tissue. It plays a central role in energy metabolism pathways and serves as a fundamental physiological marker for glomerular filtration and renal function. As an end-stage metabolic byproduct, it is freely filtered by kidneys with minimal tubular reabsorption, reflecting systemic muscle mass turnover and nitrogen balance homeostasis. [1][2]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| Water | 23 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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