CPI-613 (Devimistat) IC50 for Cell-based and Cell-free Assays

Comprehensive IC50 Values for CPI-613 (Devimistat) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.

CPI-613 (Devimistat) is a high-affinity OGDH, PDH, and DLD inhibitor. It affects TCA cycle and AMPK signaling by disrupting mitochondrial energy metabolism and increasing ROS production, effectively inhibiting tumor cell proliferation and inducing apoptosis.

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