Clinical Trials
Colchicine is supported by an extensive research portfolio comprising numerous clinical trials across early through late phases of evaluation. These investigations encompass actively recruiting, completed, and pending protocols evaluating therapeutic efficacy in inflammatory and cardiovascular indications, including gout, hyperuricemia, acute heart failure, acute myocarditis, myocardial infarction, recurrent pericarditis, and COVID-19. Sponsored by academic centers, hospital foundations, and pharmaceutical companies such as Gilead Sciences and the University of Virginia, this landscape reflects widespread interest in targeting microtubule-mediated inflammatory pathways.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT06352632 | RECRUITING | Stroke |
The George Institute |
2024-09-26 | PHASE3 |
| NCT07232069 | RECRUITING | Coronary Artery Disease Risk Factors Multiple; Coronary Artery Disease Progression; Prevention & Control; Premature Atherosclerosis |
Duke University |
2026-07-21 | PHASE3 |
| NCT06930885 | RECRUITING | Atherothrombotic Diseases; Atherosclerotic Cardiovascular Disease (ASCVD) |
Hospital do Coracao |
2025-06-12 | PHASE3 |
| NCT05949281 | ACTIVE_NOT_RECRUITING | Type 1 Diabetes; Cardiovascular Diseases; Chronic Inflammation |
Asger Lund, MD |
2023-08-29 | PHASE2 |
| NCT06855433 | RECRUITING | CPPD - Calcium Pyrophosphate Deposition Disease |
Brigham and Women's Hospital |
2026-07-20 | PHASE2 |
| NCT07349875 | RECRUITING | Coronary Artery Disease (CAD) |
Nanjing First Hospital, Nanjing Medical University |
2026-01-01 | PHASE4 |
| NCT04774159 | RECRUITING | Peripheral Arterial Disease; Atherosclerosis of Extremities; Inflammation |
Population Health Research Institute |
2021-05-06 | PHASE3 |
| NCT07536373 | RECRUITING | Chronic Limb-Threatening Ischemia |
Shin Kong Wu Ho-Su Memorial Hospital |
2026-06-02 | PHASE3 |
| NCT06578182 | RECRUITING | Osteoarthritis, Knee; Osteoarthritis, Hip |
Sint Maartenskliniek |
2025-01-01 | PHASE3 |
| NCT07035405 | NOT_YET_RECRUITING | Stroke |
Beijing Tiantan Hospital |
2025-07-04 | PHASE3 |
| NCT02939573 | RECRUITING | Primary Cutaneous Vasculitis; Cutaneous Polyarteritis Nodosa; IgA Vasculitis; Henoch-Schönlein Purpura |
University of Pennsylvania |
2017-01-01 | PHASE2 |
| NCT06998862 | RECRUITING | Chronic Kidney Disease; Cardiovascular Events |
Hospital General Universitario Gregorio Marañon |
2025-02-12 | PHASE3 |
| NCT05190991 | RECRUITING | Familial Mediterranean Fever; FMF |
R-Pharm International, LLC |
2021-10-05 | PHASE2 |
| NCT06543082 | RECRUITING | Acute Coronary Syndrome |
CHA University |
2024-08-05 | PHASE4 |
| NCT07704164 | RECRUITING | HIV Infection; Cardiovascular Diseases (CVD) |
Instituto de Investigación Hospital Universitario La Paz |
2026-06 | PHASE2 |
| NCT04381936 | RECRUITING | Pneumonia |
University of Oxford |
2020-03-19 | PHASE3 |
| NCT04875702 | RECRUITING | Gout |
Massachusetts General Hospital |
2024-02-22 | PHASE4 |
| NCT07569328 | NOT_YET_RECRUITING | CAD - Coronary Artery Disease; CABG; Colchicine |
Beijing Anzhen Hospital |
2026-09-01 | |
| NCT05618353 | RECRUITING | Coronary Artery Disease |
VA Office of Research and Development |
2023-08-21 | PHASE4 |
| NCT06587737 | NOT_YET_RECRUITING | Colchicine; ICH - Intracerebral Hemorrhage; Stroke; Dependence |
Population Health Research Institute |
2026-09-30 | PHASE3 |
| NCT07611019 | ENROLLING_BY_INVITATION | Post-Operative Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG) |
National Taiwan University Hospital |
2026-07-06 | PHASE2; PHASE3 |
| NCT07411768 | NOT_YET_RECRUITING | Transcatheter Aortic Valve Replacement; Transcatheter Heart Valve Thrombosis; Anti-inflammatory Therapy |
China National Center for Cardiovascular Diseases |
2026-03 | |
| NCT06279000 | RECRUITING | Cardiovascular Diseases; Cardiovascular Complication; Perioperative Complication; Myocardial Injury; Myocardial Injury After Noncardiac Surgery (MINS) |
Cantonal Hospital of St. Gallen |
2025-04-20 | PHASE3 |
| NCT06813079 | RECRUITING | Pancreatic Ductal Carcinoma; Advanced Cancer; Epithelial Tumor |
University Health Network, Toronto |
2025-04-07 | PHASE2 |
| NCT05855746 | RECRUITING | Acute Myocarditis |
Assistance Publique - Hôpitaux de Paris |
2024-07-16 | PHASE3 |
| NCT06763055 | RECRUITING | Intracerebral Hemorrhage; Spontaneous Intracerebral Hemorrhage; Supratentorial Intracerebral Haemorrhage; Acute Intracerebral Haemorrhage; Acute Stroke |
The George Institute |
2025-02-27 | PHASE3 |
| NCT06440694 | RECRUITING | Venous Thromboembolism |
Ottawa Hospital Research Institute |
2025-07-07 | PHASE3 |
| NCT07280572 | ENROLLING_BY_INVITATION | Post COVID Condition |
Janneke van de Wijgert |
2025-02-17 | PHASE3 |
| NCT07362966 | RECRUITING | Colchicine; Coronary Atherosclerosis Management; Clonal Hematopoiesis of Indeterminate Potential |
Shenyang Northern Hospital |
2026-06-08 | PHASE4 |
| NCT07654231 | NOT_YET_RECRUITING | Chronic Kidney Disease Mineral and Bone Disorder; Hypertension; Diabetes; Dyslipidemia; Atherosclerotic Cardiovascular Disease (ASCVD); Chronic Kidney Disease (Stage 3) |
University of Texas Southwestern Medical Center |
2026-07-01 | PHASE2 |
| NCT05633810 | RECRUITING | Diabete Type 2; Cardiovascular Diseases |
Montreal Heart Institute |
2022-12-21 | PHASE3 |
| NCT07026994 | RECRUITING | Cerebral Amyloid Angiopathy; Intracerebral Hemorrhage Lobar |
Huashan Hospital |
2025-06-18 | PHASE2 |
| NCT06802926 | RECRUITING | CABG; Graft Failure; Colchicine |
Ruijin Hospital |
2025-12-29 | PHASE4 |
| NCT06095765 | RECRUITING | Coronary Artery Disease |
AZ Sint-Jan AV |
2024-01-29 | PHASE3 |
| NCT07762807 | RECRUITING | Haemodialysis Patients; Colchicine; Feasibility Study |
King's College London |
2025-04-10 | |
| NCT05503225 | RECRUITING | ICAD - Intracranial Atherosclerotic Disease |
Chinese University of Hong Kong |
2022-11-28 | PHASE2 |
| NCT05476991 | RECRUITING | Stroke; Stroke, Ischemic; Atherosclerosis; Myocardial Infarction; Coronary Syndrome; TIA; Cardiac Disease; Cerebral Infarction |
Assistance Publique - Hôpitaux de Paris |
2023-05-17 | PHASE3 |
| NCT06666335 | WITHDRAWN | Familial Mediterranean Fever (FMF ) |
Swedish Orphan Biovitrum |
2026-03-01 | PHASE4 |
| NCT07708181 | NOT_YET_RECRUITING | Gout Arthritis |
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. |
2026-08-02 | PHASE2 |
| NCT06396858 | NOT_YET_RECRUITING | Ischemic Stroke |
Brazilian Clinical Research Institute |
2026-07 | PHASE4 |
| NCT07661030 | NOT_YET_RECRUITING | Gout |
First Affiliated Hospital of Wenzhou Medical University |
2026-07-30 | PHASE4 |
| NCT07064109 | RECRUITING | ACS - Acute Coronary Syndrome |
Shanghai Tongji Hospital, Tongji University School of Medicine |
2025-07-01 | |
| NCT07571681 | RECRUITING | Hashimoto Thyroiditis; Subacute Thyroiditis; Thyroiditis |
Mansoura University |
2026-06-15 | PHASE2; PHASE3 |
| NCT06472908 | ACTIVE_NOT_RECRUITING | Coronary Heart Disease; Percutaneous Coronary Intervention; Colchicine |
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology |
2024-07-09 | PHASE3 |
| NCT07432529 | NOT_YET_RECRUITING | Venous Thrombosis Deep (Limbs); Post-thrombotic Syndrome; Venous Thromboembolism (VTE); Venous Insufficiency |
Azienda Sanitaria Locale ASL 6, Livorno |
2026-06-01 | PHASE3 |
| NCT05850091 | ACTIVE_NOT_RECRUITING | Coronary Artery Disease |
Massachusetts General Hospital |
2023-12-07 | PHASE4 |
| NCT05873881 | RECRUITING | Heart Failure |
Hamilton Health Sciences Corporation |
2024-01-29 | PHASE3 |
| NCT07462325 | NOT_YET_RECRUITING | Coronary Heart Disease (CHD) |
Chinese Academy of Medical Sciences, Fuwai Hospital |
2026-03-01 | PHASE4 |
| NCT07476625 | NOT_YET_RECRUITING | Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis Syndrome |
Wenjie Zheng |
2026-04-01 | |
| NCT06765356 | ACTIVE_NOT_RECRUITING | Persistent Atrial Fibrillation; Paroxysmal Atrial Fibrillation; Long-standing Persistent Atrial Fibrillation |
Vivek Reddy |
2025-04-15 | PHASE4 |
| NCT05175274 | NOT_YET_RECRUITING | Coronary Artery Disease |
Qingdao Central Hospital |
2022-12-06 | PHASE3 |
| NCT05890664 | RECRUITING | Atrial Fibrillation; Cardiac Arrhythmia |
University Hospital, Basel, Switzerland |
2024-04-14 | PHASE3 |
| NCT06215989 | RECRUITING | Acute Coronary Syndrome; Unstable Angina; ST Elevation Myocardial Infarction; Non ST Segment Elevation Myocardial Infarction; Colchicine |
Beijing Anzhen Hospital |
2024-09-02 | |
| NCT06936709 | NOT_YET_RECRUITING | Osteoarthritis of Knee; Recovery Following Primary Total Knee Arthroplasty; Perioperative Pain Control |
Geisinger Clinic |
2026-12-01 | PHASE4 |
| NCT07287345 | RECRUITING | Colchicine; Inflammation in Cardiac Surgery; Post Operative Atrial Fibrillation; Inflammatory Markers; Colchicine Adverse Reaction |
Ayesha Ather |
2026-01-16 | PHASE4 |
| NCT07247734 | RECRUITING | Type 1 Diabetes; Chronic Inflammation; Insulin Sensitivity |
Asger Lund, MD |
2025-12-01 | PHASE2 |
| NCT06336733 | RECRUITING | FMF |
Assistance Publique - Hôpitaux de Paris |
2024-06-04 | PHASE3 |
| NCT05162742 | ACTIVE_NOT_RECRUITING | Aortic Valve Disease; Aortic Valve Stenosis; Aortic Valve Calcification; Inflammation; Calcification; Cardiovascular Diseases |
Radboud University Medical Center |
2022-12-22 | PHASE3 |
| NCT06090890 | RECRUITING | In-stent Restenosis |
Fu Wai Hospital, Beijing, China |
2023-10-30 | PHASE4 |
| NCT06118034 | RECRUITING | Inflammatory Response; Cardiac Disease |
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School |
2024-01-28 | PHASE3 |
| NCT06874192 | RECRUITING | Statin Adverse Reaction |
Virginia Commonwealth University |
2025-03-12 | PHASE1 |
| NCT04500665 | RECRUITING | Chronic Kidney Diseases |
Brigham and Women's Hospital |
2021-11-01 | PHASE2 |
| NCT06130059 | RECRUITING | Heart Failure; Inflammation |
University of Texas Southwestern Medical Center |
2024-04-24 | PHASE2 |
| NCT05928728 | RECRUITING | Atrial Fibrillation |
Herlev and Gentofte Hospital |
2023-07-03 | PHASE3 |
| NCT06768294 | NOT_YET_RECRUITING | Calcium Pyrophosphate Deposition Disease; Chondrocalcinosis |
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio |
2025-01 | PHASE2 |
| NCT06081049 | UNKNOWN | Heart Failure With Preserved Ejection Fraction |
Tor Biering-Sørensen |
2024-01-18 | PHASE2 |
| NCT05335148 | ACTIVE_NOT_RECRUITING | Radiation Therapy |
Rutgers, The State University of New Jersey |
2022-05-10 | PHASE1 |
| NCT06286423 | RECRUITING | Heart Failure; Decompensated Heart Failure; Heart Failure With Reduced Ejection Fraction |
University of Virginia |
2024-06 | PHASE4 |
| NCT06158698 | RECRUITING | Cardiomyopathies; Myocarditis; Inflammatory Cardiomyopathy; Heart Failure; Ventricular Arrythmia |
Niguarda Hospital |
2023-11-14 | PHASE3 |
| NCT07145229 | RECRUITING | Acute Gouty Arthritis; Gout Flare; Gout Flares; Acute Gout Flare |
Atom Therapeutics Co., Ltd |
2025-08-26 | PHASE2 |
| NCT06203977 | COMPLETED | Chronic Kidney Diseases; Renal Failure |
Hamilton Health Sciences Corporation |
2024-11-15 | PHASE2 |
| NCT05472337 | RECRUITING | Acute Coronary Syndrome |
Pontificia Universidad Catolica de Chile |
2022-08-01 | PHASE2 |
| NCT06212271 | COMPLETED | Peripheral Artery Disease |
University of Pennsylvania |
2024-09-25 | EARLY_PHASE1 |
| NCT07143136 | RECRUITING | Non ST-Segment Elevation Myocardial Infarction |
Assiut University |
2025-08-10 | EARLY_PHASE1 |
| NCT04218786 | WITHDRAWN | Myocardium; Injury; Myocardial Infarction; Myocardial Ischemia |
Shifa Tameer-e-Millat University |
2025-12 | PHASE2 |
| NCT05698680 | TERMINATED | Acute Gout |
University Medicine Greifswald |
2023-01-18 | PHASE4 |
| NCT04916522 | ACTIVE_NOT_RECRUITING | Hypertension |
Herlev and Gentofte Hospital |
2021-08-10 | PHASE2 |
| NCT06604611 | NOT_YET_RECRUITING | Heart Failure; Heart Failure With Preserved Ejection Fraction (HFPEF); Chronic Inflammation; Inflammation; Colchicine |
Dongying Zhang |
2024-10-31 | PHASE4 |
| NCT05726019 | COMPLETED | Coronary Artery Disease; Acute Coronary Syndrome; Coronary Artery Bypass; Myocardial Reperfusion; Postpericardiotomy Syndrome; Postoperative Atrial Fibrilation; Perioperative Myocardial Infarction |
University of Sao Paulo General Hospital |
2022-02-05 | PHASE2 |
| NCT04181996 | COMPLETED | Cardiovascular Diseases; Atherosclerosis; Inflammation; Diabetes |
Ottawa Heart Institute Research Corporation |
2020-08-01 | PHASE3 |
| NCT06469528 | NOT_YET_RECRUITING | Coronary Artery Disease |
King's College Hospital NHS Trust |
2024-06-24 | PHASE3 |
| NCT06217120 | UNKNOWN | Heart Failure With Preserved Ejection Fraction; Microvascular Coronary Artery Disease |
Montreal Heart Institute |
2024-03-01 | PHASE2; PHASE3 |
| NCT04073797 | UNKNOWN | Hypercholesterolemia; Hypercholesterolemia, Familial; Atherosclerosis; Carotid Artery Plaque |
University of Cambridge |
2023-03-20 | |
| NCT07129538 | RECRUITING | Familial Mediterranean Fever |
Cairo University |
2025-05-10 | |
| NCT05017571 | COMPLETED | Obesity; Insulin Resistance; Inflammation |
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) |
2021-11-08 | PHASE2 |
| NCT05637398 | COMPLETED | HFpEF - Heart Failure With Preserved Ejection Fraction; Colchicine |
I.M. Sechenov First Moscow State Medical University |
2022-12-15 | PHASE1; PHASE2 |
| NCT06025071 | UNKNOWN | Percutaneous Coronary Intervention; Multivessel Coronary Artery Disease; Elderly Patients; C-Reactive Protein |
Chinese Academy of Medical Sciences, Fuwai Hospital |
2023-09 | PHASE4 |
| NCT06798714 | RECRUITING | Coronary Artery Disease; Atrial Fibrillation; Coronary Artery Bypass Grafting; Colchicine |
Tomsk Cardiology Research Institute |
2025-01-20 | PHASE4 |
| NCT05805930 | UNKNOWN | Pericarditis |
Istituto Giannina Gaslini |
2023-06-01 | PHASE3 |
| NCT06847204 | COMPLETED | COVID - 19 |
Zaeema Kanwal |
2025-02-24 | PHASE1; PHASE2 |
| NCT04264260 | COMPLETED | Hepatocellular Carcinoma Stage IIIB; Cholangiocarcinoma, Intrahepatic; Cholangiocarcinoma; With Hepatocellular Carcinoma; Hepatocellular Carcinoma Stage IV |
Kaohsiung Medical University Chung-Ho Memorial Hospital |
2019-12-24 | PHASE2 |
| NCT06304896 | UNKNOWN | Chemotherapy Induced Systolic Dysfunction |
Arab Contractors Medical Centre |
2024-05-01 | PHASE1 |
| NCT06837623 | ACTIVE_NOT_RECRUITING | HFpEF - Heart Failure With Preserved Ejection Fraction |
Cairo University |
2024-07-01 | PHASE3 |
| NCT05785429 | COMPLETED | Overweight and Obesity |
Donders Centre for Cognitive Neuroimaging |
2022-08-02 | |
| NCT06102720 | UNKNOWN | Ischemic Stroke |
Mikhail Zykov |
2023-01-12 | PHASE4 |
| NCT06280976 | WITHDRAWN | Coronary Artery Disease; Atherosclerosis; Heart Attack |
University of Louisville |
2024-03-01 | PHASE4 |
| NCT05092776 | ACTIVE_NOT_RECRUITING | Familial Mediterranean Fever; FMF |
R-Pharm International, LLC |
2021-04-29 | PHASE2 |
| NCT05802992 | UNKNOWN | Multiple Myeloma |
Affiliated Hospital of Nantong University |
2022-03-30 | PHASE3 |
| NCT05279690 | COMPLETED | Urothelial Cancer; Metastatic Solid Tumor |
Icahn School of Medicine at Mount Sinai |
2022-02-14 | PHASE1 |
| NCT05159219 | COMPLETED | Intracranial Hemorrhages |
Population Health Research Institute |
2022-08-04 | PHASE2 |
| NCT05737680 | UNKNOWN | Pericarditis Idiopathic Recurrent |
Hippocration General Hospital |
2023-02 | PHASE3 |
| NCT06567678 | COMPLETED | Coronary Artery Disease |
The University of The West Indies |
2024-08-21 | PHASE1 |
| NCT06062277 | UNKNOWN | Ischemic Stroke; Atherosclerosis |
University College Dublin |
2023-10 | PHASE2 |
| NCT06270225 | UNKNOWN | Gout Arthritis |
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. |
2024-03-30 | PHASE2 |
| NCT06342609 | COMPLETED | Coronary Artery Disease |
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center |
2023-03-15 | PHASE4 |
| NCT07074990 | COMPLETED | Sepsis at Intensive Care Unit |
Tanta University |
2023-11-01 | |
| NCT05739929 | UNKNOWN | Coronary Artery Disease |
Helwan University |
2023-03-01 | PHASE3 |
| NCT03048825 | COMPLETED | ST Elevation Myocardial Infarction; Non ST Elevation Myocardial Infarction |
Population Health Research Institute |
2018-02-01 | PHASE3 |
| NCT05253794 | COMPLETED | Aortic Stenosis; Inflammation |
Ottawa Heart Institute Research Corporation |
2022-07-01 | PHASE2; PHASE3 |
| NCT05361772 | UNKNOWN | Colchicine; Abdominal Aortic Aneurysm; Progression |
Guangdong Provincial People's Hospital |
2022-06-01 | |
| NCT06286423 | Recruiting | Heart Failure|Decompensated Heart Failure|Heart Failure With Reduced Ejection Fraction |
University of Virginia |
2024-06 | Phase 4 |
| NCT04870424 | COMPLETED | Transcatheter Aortic Valve Replacement; Atrial Fibrillation New Onset; Pacemaker; Colchicine |
Insel Gruppe AG, University Hospital Bern |
2021-09-21 | PHASE3 |
| NCT04705987 | COMPLETED | HEART FAILURE |
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia |
2021-02-08 | PHASE3 |
| NCT05956145 | COMPLETED | Platelet Aggregation, Spontaneous; Coronary Artery Disease |
University of Sao Paulo |
2021-06-17 | |
| NCT05936268 | COMPLETED | Acute Gout; Gout Flare |
Changchun GeneScience Pharmaceutical Co., Ltd. |
2023-07-21 | PHASE2 |
| NCT05250596 | COMPLETED | Non ST Segment Elevation Acute Coronary Syndrome |
Azienda USL Toscana Centro |
2022-02-24 | PHASE2 |
| NCT02898610 | COMPLETED | Ischemic Attack, Transient; Stroke |
University College Dublin |
2016-12-12 | PHASE3 |
| NCT05936281 | COMPLETED | Gout; Gout Initiating Urate-loweringUrate-lowering Therapy |
Changchun GeneScience Pharmaceutical Co., Ltd. |
2023-07-20 | PHASE2 |
| NCT03913442 | COMPLETED | Osteoarthritis; Osteo Arthritis Knee |
NYU Langone Health |
2019-05-15 | PHASE4 |
| NCT05855746 | Not yet recruiting | Acute Myocarditis |
Assistance Publique - Hôpitaux de Paris|Hospices Civils de Lyon|Fonds de Dotation ACTION |
2024-01-22 | Phase 3 |
| NCT06020300 | UNKNOWN | STEMI |
National University of Malaysia |
2023-07-28 | PHASE4 |
| NCT06078904 | COMPLETED | Coronary Artery Disease; Percutaneous Coronary Intervention |
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology |
2023-10-10 | PHASE4 |
| NCT05459974 | UNKNOWN | Atrial Fibrillation |
Stony Brook University |
2022-06-20 | PHASE3 |
| NCT04697602 | TERMINATED | Gout |
National Taiwan University Hospital |
2021-01-20 | |
| NCT04848857 | COMPLETED | Acute Coronary Syndrome |
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology |
2021-05-03 | PHASE4 |
| NCT03310125 | COMPLETED | Atrial Fibrillation; Atrial Flutter; Myocardial Injury After Non-Cardiac Surgery |
Population Health Research Institute |
2018-02-14 | PHASE3 |
| NCT05439356 | COMPLETED | Ischemic Stroke; TIA |
Beijing Tiantan Hospital |
2022-08-11 | PHASE3 |
| NCT05418686 | COMPLETED | Mediterranean Fever; Colchicine Resistance |
Assistance Publique - Hôpitaux de Paris |
2022-12-09 | |
| NCT06020300 | Recruiting | STEMI |
National University of Malaysia |
2023-07-28 | Phase 4 |
| NCT05038449 | UNKNOWN | Covid19; Colchicine |
Shanghai Public Health Clinical Center |
2021-09-06 | |
| NCT05709509 | UNKNOWN | ST Elevation Myocardial Infarction; Colchicine; Cardiac Remodeling, Ventricular |
RSD dr. Soebandi |
2022-06-01 | PHASE4 |
| NCT04355585 | UNKNOWN | Colchicine Mechanism of Action |
Brigham and Women's Hospital |
2020-05-06 | PHASE1 |
| NCT05734612 | UNKNOWN | Reperfusion Injury, Myocardial |
Indonesia University |
2022-12-04 | PHASE3 |
| NCT06426537 | COMPLETED | ST-Elevation Myocardial Infarction |
University of Brawijaya |
2022-10-20 | EARLY_PHASE1 |
| NCT04857931 | TERMINATED | Heart Failure; Inflammation; Colchicine |
Montreal Heart Institute |
2022-06-17 | PHASE2 |
| NCT05347316 | UNKNOWN | Atherosclerosis; Inflammatory Response; Coronary Disease |
University of Sao Paulo General Hospital |
2022-03-07 | PHASE1 |
| NCT05130892 | COMPLETED | NLRP3; hsCRP; Percutaneous Coronary Intervention |
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology |
2021-11-15 | PHASE4 |
| NCT05677555 | UNKNOWN | End Stage Renal Disease on Dialysis |
Assaf-Harofeh Medical Center |
2022-11-01 | PHASE2 |
| NCT04949516 | COMPLETED | Acute Coronary Syndrome; Drug-Eluting Stents |
Wonkwang University Hospital |
2021-06-15 | PHASE4 |
| NCT04324463 | COMPLETED | Coronavirus; Severe Acute Respiratory Syndrome |
Population Health Research Institute |
2020-04-21 | PHASE3 |
| NCT04303689 | COMPLETED | Essential Hypertension |
University of Copenhagen |
2020-08-01 | |
| NCT04008316 | UNKNOWN | IgA Vasculitis |
Assistance Publique - Hôpitaux de Paris |
2019-11-12 | PHASE3 |
| NCT04155879 | UNKNOWN | Atrial Fibrillation |
Hillel Yaffe Medical Center |
2019-11 | |
| NCT05930002 | COMPLETED | COVID-19 |
Ain Shams University |
2021-07-21 | |
| NCT04516941 | TERMINATED | SARS-CoV Infection; COVID-19 |
Insel Gruppe AG, University Hospital Bern |
2021-01-21 | PHASE3 |
| NCT05911022 | COMPLETED | COVID-19 |
Ain Shams University |
2021-07-01 | |
| NCT04224545 | COMPLETED | Colchicine Adverse Reaction; Atrial Fibrillation New Onset |
Bakulev Scientific Center of Cardiovascular Surgery |
2019-12-23 | PHASE4 |
| NCT04601883 | COMPLETED | Osteoarthritis Hand; Osteoarthritis Finger |
Henning Bliddal |
2021-01-15 | PHASE4 |
| NCT05324423 | UNKNOWN | Gout |
The Affiliated Hospital of Qingdao University |
2021-10-18 | PHASE1 |
| NCT05200052 | COMPLETED | Anterior MI; Colchicine |
Ain Shams University |
2022-02-01 | PHASE4 |
| NCT05168137 | UNKNOWN | HIV Infections; Inflammatory Markers; Colchicine Adverse Reaction |
Mahidol University |
2020-02-01 | PHASE4 |
| NCT04416334 | COMPLETED | SARS-CoV-2 Infection (COVID-19) |
Instituto de Investigación Marqués de Valdecilla |
2020-08-19 | PHASE3 |
| NCT04160117 | COMPLETED | Atrial Fibrillation; Recurrence |
Population Health Research Institute |
2020-01-14 | PHASE3 |
| NCT04420624 | TERMINATED | Myocardial Infarction, Acute |
University Hospital, Montpellier |
2020-12-04 | PHASE2; PHASE3 |
| NCT03128905 | COMPLETED | Chondrocalcinosis |
Lille Catholic University |
2018-02-05 | PHASE3 |
| NCT04382443 | COMPLETED | Coronary Artery Disease; Restenosis of Coronary Artery Stent; Atherosclerosis; Acute Coronary Syndrome |
Centro de estudios en Cardiologia Intervencionista |
2020-03-12 | PHASE4 |
| NCT05118737 | UNKNOWN | COVID-19 Pneumonia |
Hamad Medical Corporation |
2021-10-01 | EARLY_PHASE1 |
| NCT03693781 | COMPLETED | Amyotrophic Lateral Sclerosis |
Azienda Ospedaliero-Universitaria di Modena |
2019-04-10 | PHASE2 |
| NCT04472611 | COMPLETED | SARS-CoV-2 |
Yale University |
2020-10-30 | PHASE3 |
| NCT03376698 | COMPLETED | Colchicine; Diabetes Mellitus, Type 2; Coronary Artery Disease; White Blood Cell; Inflammation; Diarrhea |
University of the Ryukyus |
2017-06-15 | PHASE2 |
| NCT05246072 | COMPLETED | COVID-19 |
Ain Shams University |
2021-11-01 | PHASE4 |
| NCT06054100 | COMPLETED | Acute Coronary Syndrome; STEMI |
Ain Shams University |
2020-02-01 | PHASE3 |
| NCT04906720 | COMPLETED | Atrial Fibrillation; Catheter Ablation; Pericarditis |
St. Vincent Cardiovascular Research Institute |
2021-05-20 | PHASE2 |
| NCT06731595 | COMPLETED | Atrial Fibrillation; Catheter Ablation; Pericarditis |
St. Vincent Cardiovascular Research Institute |
2021-05-20 | PHASE2 |
| NCT04756128 | COMPLETED | Covid19 |
HealthPartners Institute |
2021-01-25 | PHASE2 |
| NCT04375202 | TERMINATED | COVID-19 |
University Of Perugia |
2020-04-18 | PHASE2 |
| NCT04539873 | TERMINATED | Corona Virus Infection |
Fundación Universitaria de Ciencias de la Salud |
2021-04-30 | PHASE3 |
| NCT05151614 | COMPLETED | COVID-19 Pandemic |
University of Baghdad |
2021-04-01 | PHASE1 |
| NCT04997551 | UNKNOWN | COVID-19 Infection |
Biogipuzkoa Health Research Institute |
2020-09-08 | PHASE3 |
| NCT04322565 | COMPLETED | Coronavirus Infections; Pneumonia, Viral |
Azienda Ospedaliero-Universitaria di Parma |
2020-04-20 | PHASE2 |
| NCT04139655 | WITHDRAWN | Myocardial Infarction; Myocardial Injury; Major Adverse Cardiac Events; Infectious Complications |
University of British Columbia |
2020-09-01 | |
| NCT04818489 | UNKNOWN | Covid19; Pulmonary Fibrosis Interstitial |
ClinAmygate |
2021-03-25 | PHASE4 |
| NCT04355143 | COMPLETED | COVID-19 |
University of California, Los Angeles |
2020-05-01 | PHASE2 |
| NCT04667780 | COMPLETED | COVID-19 |
Ayub Teaching Hospital |
2020-12-01 | PHASE3 |
| NCT04867226 | COMPLETED | Coronavirus Infection |
Hawler Medical University |
2021-05-08 | PHASE2 |
| NCT04492358 | TERMINATED | Covid19 |
Maria Joyera Rodríguez |
2020-10-22 | PHASE2; PHASE3 |
| NCT04130204 | COMPLETED | Gout |
Dyve Biosciences, Inc. |
2020-02-12 | PHASE2 |
| NCT04762771 | TERMINATED | Covid19 |
Baptist Health South Florida |
2020-12-23 | PHASE1; PHASE2 |
| NCT04367168 | TERMINATED | COVID |
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran |
2020-05-27 | PHASE2 |
| NCT04328480 | COMPLETED | COVID-19 |
Estudios Clínicos Latino América |
2020-04-17 | PHASE3 |
| NCT04724629 | COMPLETED | Covid19 |
University of Sao Paulo |
2021-01-05 | PHASE3 |
| NCT04359095 | COMPLETED | COVID-19 |
Universidad Nacional de Colombia |
2020-08-18 | PHASE2; PHASE3 |
| NCT04322682 | TERMINATED | Corona Virus Infection |
Montreal Heart Institute |
2020-03-23 | PHASE3 |
| NCT03575572 | TERMINATED | Single-ventricle; Heart Diseases |
University of Michigan |
2018-08-29 | PHASE2; PHASE3 |
| NCT04360980 | COMPLETED | COVID-19 |
Shahid Beheshti University of Medical Sciences |
2020-03-20 | PHASE2 |
| NCT03704181 | UNKNOWN | Chagas Disease; Colchicine Resistance |
University of Sao Paulo General Hospital |
2018-10-01 | PHASE2 |
| NCT02282098 | COMPLETED | Atrial Fibrillation; Stroke |
Population Health Research Institute |
2014-11 | PHASE3 |
| NCT04527562 | COMPLETED | Covid19 |
Dhaka Medical College |
2020-07-14 | |
| NCT03156816 | COMPLETED | Myocardial Infarction |
Hospices Civils de Lyon |
2018-07-23 | PHASE2 |
| NCT04392141 | COMPLETED | COVID-19 |
Kermanshah University of Medical Sciences |
2020-04-01 | PHASE1; PHASE2 |
| NCT04350320 | COMPLETED | COVID19 |
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia |
2020-04-30 | PHASE3 |
| NCT02366091 | COMPLETED | Coronary Artery Disease |
Johns Hopkins University |
2015-01 | PHASE2 |
| NCT02624180 | COMPLETED | Coronary Artery Disease; Human Immunodeficiency Virus |
Johns Hopkins University |
2015-11 | PHASE2 |
| NCT04363437 | TERMINATED | Coronavirus Infection |
Maimonides Medical Center |
2020-04-26 | PHASE2 |
| NCT04403243 | COMPLETED | COVID 19 |
Lomonosov Moscow State University Medical Research and Educational Center |
2020-05-08 | PHASE2 |
| NCT03735134 | UNKNOWN | Inflammation; Myocardial Infarction |
Hillel Yaffe Medical Center |
2018-11 | |
| NCT04326790 | TERMINATED | Corona Virus Disease 19 (Covid 19) |
National and Kapodistrian University of Athens |
2020-04-03 | PHASE2 |
| NCT03905759 | UNKNOWN | Postoperative Atrial Fibrillation |
doaa rashwan |
2019-04-03 | PHASE2; PHASE3 |
| NCT02926248 | SUSPENDED | Manipulation Under Anesthesia |
Hospital for Special Surgery, New York |
2016-05 | PHASE4 |
| NCT03927677 | COMPLETED | Gout; Hyperuricemia |
LG Chem |
2019-11-05 | PHASE1 |
| NCT03933007 | TERMINATED | Gout Flare |
Assistance Publique - Hôpitaux de Paris |
2019-09-10 | PHASE4 |
| NCT02035891 | UNKNOWN | Diabetic Nephropathy |
Chongqing Medical University |
2013-12 | |
| NCT02260206 | COMPLETED | Pericardial Effusion |
Yong Seog Oh |
2014-07 | PHASE4 |
| NCT03888846 | COMPLETED | Behçet Disease Affecting Oral Mucosa |
Ipekyolu Ilac Ltd. Sti |
2019-03-25 | PHASE2 |
| NCT02594111 | COMPLETED | Coronary Artery Disease; Acute Coronary Syndrome |
VA Office of Research and Development |
2013-05-30 | PHASE4 |
| NCT01709981 | COMPLETED | Coronary Artery Disease |
NYU Langone Health |
2013-05-30 | PHASE4 |
| NCT02551094 | COMPLETED | Coronary Artery Disease; Myocardial Infarction |
Montreal Heart Institute |
2015-12-04 | PHASE3 |
| NCT04056039 | COMPLETED | Cardiovascular Diseases; Arthritis, Rheumatoid |
Hospital Central "Dr. Ignacio Morones Prieto" |
2018-08-14 | PHASE2 |
| NCT01935700 | COMPLETED | Hepatocellular Carcinoma; Metastasis; Invasion |
Kaohsiung Medical University Chung-Ho Memorial Hospital |
2013-06-06 | PHASE2 |
| NCT02442921 | UNKNOWN | Diabetic Nephropathies |
Sheba Medical Center |
2016-02-22 | PHASE1; PHASE2 |
| NCT03015831 | TERMINATED | Atrial Fibrillation; Cardiac Surgery; Colchicine Adverse Reaction |
Jordan Collaborating Cardiology Group |
2017-10-02 | PHASE3 |
| NCT03226899 | TERMINATED | Gout; Chronic Kidney Disease (CKD) |
Ironwood Pharmaceuticals, Inc. |
2017-07-19 | PHASE4 |
| NCT02995512 | WITHDRAWN | Myocardial Infarction |
NYU Langone Health |
2017-05-01 | PHASE4 |
| NCT02582190 | WITHDRAWN | Atrial Fibrillation |
Elpen Pharmaceutical Co. Inc. |
2017-12-02 | PHASE3 |
| NCT02153983 | COMPLETED | Obesity; Metabolic Disease |
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) |
2014-05-31 | PHASE1; PHASE2 |
| NCT03659058 | COMPLETED | Fibrosis, Liver |
Zagazig University |
2016-03-02 | |
| NCT03131583 | COMPLETED | Gout |
Jiangsu HengRui Medicine Co., Ltd. |
2017-02-17 | PHASE1 |
| NCT02500641 | COMPLETED | Gout |
Menarini International Operations Luxembourg SA |
2015-08-17 | PHASE4 |
| NCT02911857 | COMPLETED | Periodic Fevers Syndrome |
Novartis Pharmaceuticals |
2016-10-03 | PHASE3 |
| NCT01755949 | COMPLETED | Atrial Fibrillation |
Mayo Clinic |
2013-03 | PHASE2 |
| NCT02177266 | TERMINATED | Atrial Fibrillation; Post-pericardiotomy Syndrome; Constriction |
Mayo Clinic |
2015-05 | PHASE3 |
| NCT01906749 | UNKNOWN | Acute Coronary Syndrome |
Maria Vittoria Hospital |
2013-06 | PHASE4 |
| NCT02363725 | COMPLETED | Acute Myocardial Infarction |
University Hospital, Montpellier |
2014-12 | PHASE2 |
| NCT01994226 | COMPLETED | Gout |
Keele University |
2014-01 | PHASE4 |
| NCT02095522 | WITHDRAWN | NSTEMI |
Tel-Aviv Sourasky Medical Center |
2014-03 | |
| NCT02139046 | COMPLETED | Gout |
Takeda |
2014-04 | PHASE3 |
| NCT02330796 | COMPLETED | Gout |
Revive Therapeutics, Ltd. |
2015-04 | PHASE2 |
| NCT02176460 | COMPLETED | Knee Osteoarthritis |
Singapore General Hospital |
2013-10 | PHASE2; PHASE3 |
| NCT02128490 | COMPLETED | Gout; Moderate Renal Impairment |
Takeda |
2014-05 | PHASE2 |
| NCT02162303 | COMPLETED | Atherosclerotic Vascular Disease |
Montreal Heart Institute |
2014-05 | PHASE2 |
| NCT01362608 | TERMINATED | Gouty Arthritis |
Novartis Pharmaceuticals |
2011-06-20 | PHASE3 |
| NCT01985425 | COMPLETED | Atrial Fibrillation; Thoracic Surgery |
Population Health Research Institute |
2014-04 | PHASE3 |
| NCT02281305 | UNKNOWN | Acute Myocardial Infarction |
G.Gennimatas General Hospital |
2014-10 | PHASE4 |
| NCT01936285 | UNKNOWN | Acute Myocardial Infarction |
G.Gennimatas General Hospital |
2013-07 | PHASE4 |
| NCT02063997 | COMPLETED | Gout |
Gilead Sciences |
2014-03 | PHASE2 |
| NCT03021343 | COMPLETED | Arrhythmia |
Jordan Collaborating Cardiology Group |
2012-10 | PHASE3 |
| NCT02140372 | COMPLETED | Healthy |
NYU Langone Health |
2014-05 | PHASE4 |
| NCT02175589 | UNKNOWN | Familial Mediterranean Fever |
Rambam Health Care Campus |
2014-06 | PHASE2 |
| NCT02252835 | COMPLETED | Gout; Hyperuricemia |
Gilead Sciences |
2014-08 | PHASE2 |
| NCT01705756 | COMPLETED | Familial Mediterranean Fever |
Sheba Medical Center |
2012-11 | PHASE3 |
| NCT01112982 | COMPLETED | Gout |
University of South Florida |
2010-05 | PHASE4 |
| NCT02021084 | WITHDRAWN | Familial Mediterranean Fever (FMF ) |
Rambam Health Care Campus |
2013-12 | |
| NCT01005121 | UNKNOWN | Diabetic Nephropathy |
Prof.Avi Livneh |
2009-12 | PHASE2 |
| NCT01552187 | UNKNOWN | Cardiac Surgery; Post-pericardiotomy Syndrome; Atrial Fibrillation; Pericardial Effusion; Pleural Effusion |
Maria Vittoria Hospital |
2012-03 | PHASE3 |
| NCT02122484 | COMPLETED | Elective Coronary Artery Bypass Graft Surgery |
G.Gennimatas General Hospital |
2013-11 | PHASE4 |
| NCT02083510 | COMPLETED | Hypertriglyceridemia; Gout; Pericarditis |
Scripps Translational Science Institute |
2014-02 | EARLY_PHASE1 |
| NCT02060552 | COMPLETED | Primary Gout |
Tongji Hospital |
2013-01 | PHASE4 |
| NCT01481233 | WITHDRAWN | Prostate Cancer |
Milton S. Hershey Medical Center |
2013-05 | PHASE2 |
| NCT01470989 | COMPLETED | Acute Gouty Arthritis Flares |
Novartis Pharmaceuticals |
2011-11 | PHASE3 |
| NCT02602028 | COMPLETED | Familial Mediterranean Fever |
Saglik Bilimleri Universitesi Gulhane Tip Fakultesi |
2011-04 | PHASE4 |
| NCT01266694 | COMPLETED | Pericardial Effusion |
French Cardiology Society |
2011-04 | PHASE4 |
| NCT00840489 | TERMINATED | Chronic Hepatitis C |
Hospital Universitario Ramon y Cajal |
2009-01 | PHASE2 |
| NCT01451645 | COMPLETED | Intercritical Gout |
Regeneron Pharmaceuticals |
2011-10 | PHASE4 |
| NCT01601132 | COMPLETED | Healthy |
Takeda |
2012-05 | PHASE4 |
| NCT00128453 | COMPLETED | Pericarditis |
Azienda Sanitaria Locale 3, Torino |
2005-08 | PHASE3 |
| NCT01399008 | COMPLETED | Gout |
Gilead Sciences |
2011-06 | PHASE2 |
| NCT01148797 | COMPLETED | Colchicine Resistant/Intolerant Familial Mediterranean Fever |
Novartis Pharmaceuticals |
2010-12 | PHASE2 |
| NCT01160276 | COMPLETED | Renal Replacement Therapies |
Assistance Publique - Hôpitaux de Paris |
2010-05 | PHASE1 |
| NCT00235079 | COMPLETED | Pericarditis; Recurrence |
Azienda Sanitaria Locale 3, Torino |
2005-11 | PHASE4 |
| NCT01932268 | COMPLETED | Chronic Kidney Disease; Tuberculosis |
Seoul National University Hospital |
2011-01 | PHASE2 |
| NCT01075906 | COMPLETED | Familial Mediterranean Fever |
Mutual Pharmaceutical Company, Inc. |
2010-08 | PHASE1 |
| NCT01336686 | COMPLETED | Hyperuricemia; Gout |
Gilead Sciences |
2011-05 | PHASE2 |
| NCT00983177 | UNKNOWN | Calcific Tendonitis |
Bnai Zion Medical Center |
2010-03 | |
| NCT01416402 | COMPLETED | Hyperuricemia; Gout |
Gilead Sciences |
2011-08 | PHASE2 |
| NCT01088880 | COMPLETED | Familial Mediterranean Fever |
Novartis Pharmaceuticals |
2010-04 | PHASE2 |
| NCT01084278 | COMPLETED | Pharmacokinetics |
Takeda |
2010-05 | PHASE4 |
| NCT01173107 | COMPLETED | Chronic Kidney Disease |
Seoul National University Hospital |
2010-12 | PHASE4 |
| NCT01080131 | COMPLETED | Acute Gout |
Novartis Pharmaceuticals |
2010-03 | PHASE3 |
| NCT01029652 | COMPLETED | Acute Gout |
Novartis Pharmaceuticals |
2009-12 | PHASE3 |
| NCT00819585 | COMPLETED | Gout |
Novartis Pharmaceuticals |
2008-12 | PHASE2 |
| NCT00128427 | COMPLETED | Postpericardiotomy Syndrome |
Azienda Sanitaria Locale 3, Torino |
2005-06 | PHASE3 |
| NCT01130051 | COMPLETED | Healthy |
Mutual Pharmaceutical Company, Inc. |
2010-05 | PHASE1 |
| NCT01123395 | COMPLETED | Healthy |
Mutual Pharmaceutical Company, Inc. |
2010-05 | PHASE1 |
| NCT00179413 | COMPLETED | Hepatitis C Virus; Advanced Fibrosis; Cirrhosis |
Beth Israel Deaconess Medical Center |
2000-01-15 | PHASE4 |
| NCT01001052 | COMPLETED | Healthy |
Mutual Pharmaceutical Company, Inc. |
2009-10 | PHASE1 |
| NCT00754819 | COMPLETED | Acute Coronary Syndrome |
Hamilton Health Sciences Corporation |
2008-04 | PHASE2; PHASE3 |
| NCT00798369 | COMPLETED | Acute Gout |
Novartis |
2008-11 | PHASE2 |
| NCT00960193 | COMPLETED | Healthy |
Mutual Pharmaceutical Company, Inc. |
2009-02 | PHASE1 |
| NCT00128414 | COMPLETED | Pericarditis; Recurrence |
Azienda Sanitaria Locale 3, Torino |
2005-08 | PHASE3 |
| NCT00960323 | COMPLETED | Healthy |
Mutual Pharmaceutical Company, Inc. |
2009-02 | PHASE1 |
| NCT00983242 | COMPLETED | Pharmacokinetics |
Mutual Pharmaceutical Company, Inc. |
2008-09 | PHASE1 |
| NCT00984009 | COMPLETED | Pharmacokinetics |
Mutual Pharmaceutical Company, Inc. |
2008-09 | PHASE1 |
| NCT00983931 | COMPLETED | Pharmacokinetics; Healthy |
Mutual Pharmaceutical Company, Inc. |
2008-08 | PHASE1 |
| NCT00983905 | COMPLETED | Pharmacokinetics |
Mutual Pharmaceutical Company, Inc. |
2008-08 | PHASE1 |
| NCT00983294 | COMPLETED | Pharmacokinetics |
Mutual Pharmaceutical Company, Inc. |
2008-07 | PHASE1 |
| NCT00723268 | UNKNOWN | Oral Aphthae |
Mashhad University of Medical Sciences |
2007-05 | PHASE2 |
| NCT00983372 | COMPLETED | Healthy; Adult; Volunteer; Colchicine; Pharmacokinetics; Diltiazem; Cytochrome p450 3A4; P-glycoprotein |
Mutual Pharmaceutical Company, Inc. |
2008-08 | PHASE1 |
| NCT00983216 | COMPLETED | Pharmacokinetics |
Mutual Pharmaceutical Company, Inc. |
2008-07 | PHASE1 |
| NCT00983515 | COMPLETED | Pharmacokinetics |
Mutual Pharmaceutical Company, Inc. |
2008-07 | PHASE1 |
| NCT01040845 | COMPLETED | Pharmacokinetics |
Mutual Pharmaceutical Company, Inc. |
2007-08 | PHASE1 |
| NCT00984061 | COMPLETED | Pharmacokinetics |
Mutual Pharmaceutical Company, Inc. |
2007-11 | PHASE1 |
| NCT01018420 | COMPLETED | Pharmacokinetics |
Mutual Pharmaceutical Company, Inc. |
2007-11 | PHASE1 |
| NCT00506883 | COMPLETED | Gout |
Takeda |
2007-04 | PHASE3 |
| NCT01017003 | COMPLETED | Pharmacokinetics |
Mutual Pharmaceutical Company, Inc. |
2007-09 | PHASE1 |
| NCT01021020 | COMPLETED | Healthy |
Mutual Pharmaceutical Company, Inc. |
2007-09 | PHASE1 |
| NCT01017042 | COMPLETED | Pharmacokinetics |
Mutual Pharmaceutical Company, Inc. |
2007-09 | PHASE1 |
| NCT00700297 | COMPLETED | Behcet's Syndrome |
Tehran University of Medical Sciences |
2002-08 | PHASE2 |
| NCT00370201 | UNKNOWN | Rhegmatogenous Retinal Detachment |
Shahid Beheshti University of Medical Sciences |
2004-03 | PHASE3 |
| NCT00004368 | UNKNOWN | Cirrhosis; Liver Cirrhosis |
National Center for Research Resources (NCRR) |
1990-05 | PHASE1 |
| NCT00370760 | UNKNOWN | Proliferative Vitreoretinopathy |
Shahid Beheshti University of Medical Sciences |
2006-09 | PHASE3 |
| NCT00000577 | WITHDRAWN | Asthma; Lung Diseases |
Milton S. Hershey Medical Center |
1993-09 | PHASE3 |
| NCT00004748 | COMPLETED | Liver Cirrhosis, Biliary |
National Center for Research Resources (NCRR) |
1989-11 | PHASE3 |
(data from https://clinicaltrials.gov, updated on 2026-07-08)
Check the
Colchicine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Compliance for Clinical Use
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
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Note: Technical data last updated: Sep 1, 2026.