Synonyms: CD227,MUC-1
Clivatuzumab (Anti-MUC1) is a humanized anti-mucin monoclonal antibody targeting an epitope in the MUC1 antigen expressed in most pancreatic cancers. MW: 145.5 kD.
| Featured Inhibitors | Y-27632 Dihydrochloride SB431542 CHIR-99021 (Laduviglusib) RMC-7977 RMC-6236 (Daraxonrasib) MRTX1133 MG132 Z-VAD-FMK VT3989 IAG933 |
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| Description |
Clivatuzumab (Anti-MUC1) is a humanized anti-mucin monoclonal antibody targeting an epitope in the MUC1 antigen expressed in most pancreatic cancers. MW: 145.5 kD.
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| CAS No. | 1622075-09-5 |
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| Molecular Weight | 145.5 kDa |
| Isotype | Human IgG1 |
| Source | CHO |
| Purification | AKTA |
| Sterility | 0.2 μM filtered |
| Formulation | 100 mM Pro-Ac, 20mM Arg, pH5.0 |
| Storage (From the date of receipt) |
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)
| NCT Number | Recruitment | interventions | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|---|
| NCT05812326 | COMPLETED | Drug: AJMUC1- PD-1 gene knockout anti-MUC1 CAR-T cells | Advanced Breast Cancer; Breast Neoplasm Malignant Female | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2019-05-17 | PHASE1; PHASE2 |
| NCT03706326 | UNKNOWN | Advanced Esophageal Cancer | The First Affiliated Hospital of Guangdong Pharmaceutical University | 2018-09-28 | PHASE1; PHASE2 | |
| NCT03525782 | UNKNOWN | Drug: PD-1 mAb | Lung Neoplasm Malignant; Non-small Cell Lung Cancer | The First Affiliated Hospital of Guangdong Pharmaceutical University | 2018-02-01 | PHASE1; PHASE2 |
| NCT02544880 | COMPLETED | Drug: Tadalafil | Head and Neck Squamous Cell Carcinoma; Head and Neck Cancer | Donald T. Weed, MD, FACS | 2016-04-25 | PHASE1 |
| NCT02617134 | UNKNOWN | Malignant Glioma of Brain; Colorectal Carcinoma; Gastric Carcinoma | PersonGen BioTherapeutics (Suzhou) Co., Ltd. | 2015-11 | PHASE1; PHASE2 | |
| NCT02587689 | UNKNOWN | Hepatocellular Carcinoma; Non-small Cell Lung Cancer; Pancreatic Carcinoma; Triple-Negative Invasive Breast Carcinoma | PersonGen BioTherapeutics (Suzhou) Co., Ltd. | 2015-10 | PHASE1; PHASE2 |
(data from https://clinicaltrials.gov, updated on 2023-04-13)
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