Cisplatin is a cytotoxic DNA crosslinker. It affects p53 and DDR signaling by forming DNA adducts, promoting cell apoptosis.
Comprehensive IC50 Values for Cisplatin Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
Cisplatin is a cytotoxic DNA crosslinker. It affects p53 and DDR signaling by forming DNA adducts, promoting cell apoptosis.