Clinical Trials

Cisplatin represents a heavily investigated chemotherapeutic backbone evaluated across numerous clinical trials spanning Early Phase 1 through Phase 4. Sponsored by government institutes, cooperative groups, and academic medical centers, these studies assess treatment regimens for urothelial carcinoma, non-small cell lung cancer, head and neck cancer, neuroendocrine tumors, melanoma, and breast cancer, as well as interventions for toxicities such as hearing loss. Recruitment statuses encompass active, recruiting, and completed studies across the entire developmental continuum.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04198766 RECRUITING
Solid Tumor; Non-Small Cell Lung Cancer; Head and Neck Cancer; Melanoma; Gastric Cancer; Renal Cell Carcinoma; Urothelial Carcinoma; Resectable Non-Small-Cell Lung Cancer
Inhibrx Biosciences, Inc
2019-12-10 PHASE1; PHASE2
NCT07801235 RECRUITING
Head and Neck (HNSCC)
King Hussein Cancer Center
2026-08-20
NCT07340515 RECRUITING
Nasopharyngeal Carcinoma (NPC)
Man Hu
2025-12-15 PHASE3
NCT07177443 NOT_YET_RECRUITING
Locally Advanced Nasopharyngeal Carcinoma
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
2025-09-25 PHASE3
NCT07063745 RECRUITING
Metastatic Non-small Cell Lung Cancer With MTAP Deletion
Bristol-Myers Squibb
2026-01-02 PHASE2; PHASE3
NCT07474064 NOT_YET_RECRUITING
Muscle Invasive Bladder Cancer (MIBC)
chenxu
2026-03-26 PHASE2
NCT07517419 ENROLLING_BY_INVITATION
Gastric Cancer Peritoneal Metastases
Chinese University of Hong Kong
2021-10-11 PHASE2
NCT07782346 NOT_YET_RECRUITING
Advanced Solid Malignancies
National Health Research Institutes, Taiwan
2026-10-01 PHASE1
NCT07001618 RECRUITING
NSCLC (Advanced Non-small Cell Lung Cancer)
Gustave Roussy, Cancer Campus, Grand Paris
2025-11-17 PHASE2
NCT07709585 NOT_YET_RECRUITING
Advanced Non-small Cell Lung Cancer (NSCLC); EGFR Exon 19 Deletion Mutation; EGFR Exon 21 Mutation; EGFR Exon 21 L858R Mutation
Guangzhou University of Traditional Chinese Medicine
2026-07-05 PHASE2
NCT06561386 RECRUITING
Non-small Cell Lung Cancer
Bristol-Myers Squibb
2024-10-07 PHASE3
NCT04107077 RECRUITING
Gastric Cancer; Peritoneal Carcinomatosis
University of Chicago
2025-09-09 PHASE2
NCT06702033 RECRUITING
HPV-Related Oropharynx Squamous Cell Carcinoma
Washington University School of Medicine
2025-04-10 PHASE2
NCT02998385 ACTIVE_NOT_RECRUITING
HNSCC
Groupe Oncologie Radiotherapie Tete et Cou
2017-01-20 PHASE3
NCT06647563 NOT_YET_RECRUITING
Squamous Cell Carcinoma of Head and Neck
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
2024-11-01 PHASE3
NCT04325425 RECRUITING
Neuroendocrine Carcinoma
Centre Hospitalier Universitaire Dijon
2020-09-01 PHASE2
NCT07276399 RECRUITING
Squamous Cell Carcinoma of Head and Neck
Janssen Research & Development, LLC
2025-12-03 PHASE3
NCT07129993 RECRUITING
Urothelial Cancer; Bladder Cancer
Daiichi Sankyo
2025-09-26 PHASE2; PHASE3
NCT04595981 WITHDRAWN
SCCHN; Squamous Cell Carcinoma
University of Alabama at Birmingham
2027-05 PHASE2
NCT06632327 ACTIVE_NOT_RECRUITING
Resectable Lung Non-Small Cell Carcinoma; Stage II Lung Cancer AJCC v8; Stage IIIA Lung Cancer AJCC v8; Stage IIIB Lung Cancer AJCC v8
Alliance for Clinical Trials in Oncology
2024-12-11 PHASE3
NCT07514793 NOT_YET_RECRUITING
Mesothelioma
Fudan University
2026-04 PHASE2
NCT06323369 RECRUITING
Head and Neck Squamous Cell Carcinoma
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
2024-03-25 PHASE2
NCT07463313 NOT_YET_RECRUITING
Thymoma and Thymic Carcinoma
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
2026-03 PHASE2; PHASE3
NCT06996782 RECRUITING
Advanced or Metastatic Non-small Cell Lung Cancer
AstraZeneca
2025-11-24 PHASE1; PHASE2
NCT07106762 RECRUITING
Urothelial Cancer
Bristol-Myers Squibb
2025-09-30 PHASE2; PHASE3
NCT07622186 RECRUITING
Non-Small Cell Lung Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
2026-07-15 PHASE2
NCT06137378 RECRUITING
Squamous Cell Carcinoma of Head and Neck; Hypopharyngeal Squamous Cell Carcinoma; Laryngeal Squamous Cell Carcinoma Stage III; Laryngeal Squamous Cell Carcinoma Stage IV; Squamous Cell Carcinoma of Larynx; Squamous Cell Carcinoma of the Larynx; Squamous Cell Carcinoma of the Larynx Stage III; Squamous Cell Carcinoma of the Larynx Stage IV; Laryngeal Squamous Cell Carcinoma; Laryngectomy; Status; Laryngeal Cancer; Laryngeal Neoplasms
University of Leipzig
2024-04-17 PHASE2
NCT06878196 NOT_YET_RECRUITING
Uterine Cervical Neoplasm
Obstetrics & Gynecology Hospital of Fudan University
2025-03-10
NCT07028281 RECRUITING
Malignant Solid Tumors
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
2025-07-08 PHASE2
NCT06535607 RECRUITING
Sub-study 1 Cervical Cancer (Volrustomig Monotherapy); Sub-study 2 Head and Neck Squamous Cell Carcinoma (Volrustomig Monotherapy); Sub-study 3 Head and Neck Squamous Cell Carcinoma (Volrustomig in Combination With Chemotherapy); Sub-study 4 Esophageal Squamous Cell Carcinoma (Volrustomig in Combination With Chemotherapy); Sub-study 5 Unresectable Pleural Mesothelioma (Volrustomig Monotherapy)
AstraZeneca
2024-08-22 PHASE2
NCT07036380 RECRUITING
Advanced Biliary Tract Carcinoma
Centre Hospitalier Universitaire de Besancon
2025-12-22 PHASE2
NCT06393816 RECRUITING
Large Cell Neuroendocrine Carcinoma of the Lung
Centre Leon Berard
2024-06-13 PHASE2
NCT06699212 RECRUITING
Recurrent Head and Neck Squamous Cell Carcinoma
Rakuten Medical, Inc.
2024-12-24 PHASE3
NCT06561763 NOT_YET_RECRUITING
High Risk Locally Advanced Nasopharyngeal Carcinoma
Sun Yat-sen University
2024-08-20 PHASE3
NCT06204614 ENROLLING_BY_INVITATION
Muscle Invasive Bladder Urothelial Carcinoma
Brigham and Women's Hospital
2024-06-14 EARLY_PHASE1
NCT07336147 RECRUITING
Female
Chang Gung Memorial Hospital
2025-12-22 PHASE2
NCT05502237 ACTIVE_NOT_RECRUITING
Non-small Cell Lung Cancer
Gilead Sciences
2022-10-12 PHASE3
NCT04811703 RECRUITING
Metastatic Ovarian Carcinoma; Peritoneal Carcinomatosis; Stage III Ovarian Cancer; Stage IV Ovarian Cancer; Stage III Fallopian Tube Cancer; Stage IV Fallopian Tube Cancer; Metastatic Malignant Neoplasm in the Peritoneum
Hospices Civils de Lyon
2021-07-30 PHASE1
NCT06084845 WITHDRAWN
Head and Neck Squamous Cell Carcinoma; Hypopharyngeal Squamous Cell Carcinoma; Laryngeal Squamous Cell Carcinoma; Oral Cavity Squamous Cell Carcinoma; Oropharyngeal Squamous Cell Carcinoma; Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8; Stage III Hypopharyngeal Carcinoma AJCC v8; Stage III Laryngeal Cancer AJCC v8; Stage III Lip and Oral Cavity Cancer AJCC v8; Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8; Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8; Stage IV Hypopharyngeal Carcinoma AJCC v8; Stage IV Laryngeal Cancer AJCC v8; Stage IV Lip and Oral Cavity Cancer AJCC v8; Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8
ECOG-ACRIN Cancer Research Group
2024-04-12 PHASE2
NCT07383116 NOT_YET_RECRUITING
Non Squamous Non-small Cell Lung Cancer
Shanghai Huaota Biopharmaceutical Co., Ltd.
2026-01-15 PHASE3
NCT06464068 RECRUITING
Extrapulmonary Small Cell Carcinoma
Gruppo Oncologico Italiano di Ricerca Clinica
2024-01-16 PHASE2
NCT01154920 ACTIVE_NOT_RECRUITING
Head and Neck Squamous Cell Carcinoma
M.D. Anderson Cancer Center
2010-07-09 PHASE2
NCT02734537 RECRUITING
Head and Neck Squamous Cell Carcinoma; Hypopharyngeal Squamous Cell Carcinoma; Laryngeal Squamous Cell Carcinoma; Laryngeal Squamous Cell Carcinoma, Spindle Cell Variant; Lip and Oral Cavity Squamous Cell Carcinoma; p16INK4a Negative Oropharyngeal Squamous Cell Carcinoma; Stage III Hypopharyngeal Carcinoma AJCC v8; Stage III Laryngeal Cancer AJCC v8; Stage III Lip and Oral Cavity Cancer AJCC v8; Stage III Oral Cavity Verrucous Carcinoma; Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8; Stage IVA Hypopharyngeal Carcinoma AJCC v8; Stage IVA Laryngeal Cancer AJCC v8; Stage IVA Lip and Oral Cavity Cancer AJCC v8; Stage IVA Oral Cavity Verrucous Carcinoma; Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8
ECOG-ACRIN Cancer Research Group
2016-11-23 PHASE2
NCT07598318 NOT_YET_RECRUITING
Cholangiocarcinoma
Sir Run Run Shaw Hospital
2026-05-20 PHASE2; PHASE3
NCT06692491 NOT_YET_RECRUITING
Rare Tumour
Peking University Shenzhen Hospital
2025-01-01 PHASE2
NCT07172412 NOT_YET_RECRUITING
Extensive Stage Lung Small Cell Cancer
Tianjin Medical University Cancer Institute and Hospital
2025-11 PHASE2
NCT06764355 RECRUITING
ESCC; Total Neoadjuvant Treatment; Pathological Complete Response
National Taiwan University Hospital
2025-07-23 PHASE2
NCT07481058 RECRUITING
Esophageal Squamous Cell Carcinoma (ESCC)
Beijing Konruns Pharmaceutical Co., Ltd.
2025-12-12 PHASE2
NCT02999087 ACTIVE_NOT_RECRUITING
HNSCC
Groupe Oncologie Radiotherapie Tete et Cou
2017-09-14 PHASE3
NCT04605770 RECRUITING
Sarcoma,Soft Tissue
Yonsei University
2020-12-22 PHASE2
NCT07241767 RECRUITING
Lung Cancer
Jiangsu HengRui Medicine Co., Ltd.
2025-11-12 PHASE2
NCT05599984 ACTIVE_NOT_RECRUITING
Advanced Solid Tumors
AbbVie
2022-12-05 PHASE1
NCT07699276 RECRUITING
Cancer (Solid Tumors); Vomiting; Cisplatin; Olanzapine
Mahidol University
2026-02-10 PHASE2
NCT02215265 ACTIVE_NOT_RECRUITING
Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer
Lisette Nixon
2015-10 PHASE3
NCT04465968 NOT_YET_RECRUITING
Superior Sulcus Tumor; Non-small Cell Lung Cancer Stage IIB; Non Small Cell Lung Cancer Stage III
National Cancer Center Hospital East
2020-09-01 PHASE3
NCT05487391 RECRUITING
Carcinoma, Non-Small-Cell Lung
Qilu Pharmaceutical Co., Ltd.
2022-12-08 PHASE3
NCT04392622 RECRUITING
Xerostomia
Stanford University
2021-02-15 PHASE1
NCT07061535 RECRUITING
Extensive-stage Small Cell Lung Cancer (ES-SCLC); Extensive Stage Lung Small Cell Cancer; Extensive-Stage Small-Cell Lung Cancer; Extensive Disease Small Cell Lung Cancer
Second Affiliated Hospital, Zhejiang University, School of Medicine
2025-07-30 PHASE2
NCT06057038 ACTIVE_NOT_RECRUITING
Malignant Solid Tumor
Genmab
2023-11-24 PHASE1
NCT07088731 NOT_YET_RECRUITING
Cervical Carcinoma
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
2025-09 PHASE2
NCT05198830 ACTIVE_NOT_RECRUITING
Lung Adenocarcinoma; Lung Large Cell Carcinoma; Lung Non-Squamous Non-Small Cell Carcinoma; Stage III Lung Cancer AJCC v8
National Cancer Institute (NCI)
2022-12-15 PHASE2
NCT06502080 NOT_YET_RECRUITING
Biliary Tract Cancer
Shanghai Zhongshan Hospital
2024-07 PHASE2
NCT06415318 RECRUITING
Penile Cancer
Sun Yat-sen University
2024-05-31 PHASE2
NCT04999761 RECRUITING
Advanced or Metastatic Solid Tumor; Pancreatic Ductal Adenocarcinoma; Colorectal Cancer; Non-small Cell Lung Cancer; Gastric Cancer; Alveolar Soft Part Sarcoma; Esophageal Cancer; Head and Neck Cancer; Biliary Tract Cancer
Taiho Pharmaceutical Co., Ltd.
2021-06-01 PHASE1
NCT06851247 RECRUITING
Nasopharyngeal Carcinoma
Sun Yat-sen University
2025-01-03 PHASE2
NCT02151084 ACTIVE_NOT_RECRUITING
Biliary Tract Carcinoma; Gallbladder Carcinoma
University Health Network, Toronto
2014-11 PHASE2
NCT02341989 ACTIVE_NOT_RECRUITING
Testicular Neoplasms; Seminoma
St. Olavs Hospital
2015-04-08 PHASE3
NCT06375109 NOT_YET_RECRUITING
Limited-stage Small-cell Lung Cancer
Beijing Chest Hospital, Capital Medical University
2024-04-16 PHASE2
NCT06983210 RECRUITING
Urothelial Carcinoma Bladder; Urothelial Carcinoma of the Renal Pelvis and Ureter; Urothelial Carcinoma Urethra; Urothelial Carcinoma Recurrent
Nagoya University
2025-05-01 PHASE2
NCT07059221 RECRUITING
Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Suzhou Suncadia Biopharmaceuticals Co., Ltd.
2025-07-11 PHASE1; PHASE2
NCT06239727 RECRUITING
Nasopharyngeal Carcinoma
Sun Yat-sen University
2024-03-01 PHASE3
NCT04241185 ACTIVE_NOT_RECRUITING
Urinary Bladder Neoplasms
Merck Sharp & Dohme LLC
2020-05-19 PHASE3
NCT05129748 RECRUITING
Ototoxic Hearing Loss
Sunnybrook Health Sciences Centre
2023-02-15 PHASE2
NCT03520491 ACTIVE_NOT_RECRUITING
Bladder Cancer
Memorial Sloan Kettering Cancer Center
2018-04-25 PHASE2
NCT07025174 RECRUITING
Bile Duct Carcinoma; Gall Bladder Cancer; Biliary Tract Cancer; Cholangiocarcinoma
First Affiliated Hospital of Zhejiang University
2025-06-01 PHASE2
NCT04460352 RECRUITING
Esophageal Squamous Cell Carcinoma
Karolinska University Hospital
2020-11-27 PHASE3
NCT06684327 RECRUITING
Paget Disease, Extramammary; Rhabdomyosarcoma; Testicular Cancer; Penile Cancer; Urachal Cancer
Fudan University
2024-11-30 PHASE2
NCT06652048 RECRUITING
Non-Small Cell Lung Cancer
Jialei Wang
2024-10-01 PHASE2
NCT06623162 NOT_YET_RECRUITING
Mibc; Muscle Invasive Bladder Cancer
Fundación de investigación HM
2024-12 PHASE2
NCT06943820 RECRUITING
Non-small Cell Lung Cancer Stage IIIB/IV; Head and Neck Squamous Cell Carcinoma (HNSCC); Colorectal Adenocarcinoma; Advanced Solid Tumors
Akeso
2025-05-21 PHASE1; PHASE2
NCT07136285 RECRUITING
SCLC, Extensive Stage
Newsoara HYK Biopharmaceutical (Shanghai) Co., Ltd.
2023-07-24 PHASE1; PHASE2
NCT06156514 RECRUITING
Locally Advanced Cervical Cancer; Gemcitabine; Chemo-radiotherapy
National Institute of Cancerología
2019-11-06 PHASE3
NCT04162015 ACTIVE_NOT_RECRUITING
Malignant Pleural Mesothelioma
Memorial Sloan Kettering Cancer Center
2019-11-12 PHASE1
NCT06704620 NOT_YET_RECRUITING
Advanced and Metastatic NSCLC
Tianjin Medical University Cancer Institute and Hospital
2024-12 PHASE3
NCT04129502 ACTIVE_NOT_RECRUITING
Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)
Takeda
2020-01-10 PHASE3
NCT06611345 RECRUITING
Biliary Tract Cancers (BTC)
Jiangsu Healthy Life Innovation Medical Technology Co., Ltd
2024-10-21
NCT06489197 RECRUITING
ESCC; Advanced Esophageal Squamous Cell Carcinoma
Tianjin Medical University Cancer Institute and Hospital
2024-11-16 PHASE2
NCT06447662 ACTIVE_NOT_RECRUITING
Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung
Pfizer
2024-06-27 PHASE1
NCT05451043 RECRUITING
Pancreatic Cancer; Hepatocellular Cancer; Biliary Tract Cancer; Cholangiocarcinoma
AHS Cancer Control Alberta
2023-07-05 PHASE2
NCT06896890 RECRUITING
NSCLC (advanced Non-small Cell Lung Cancer); Stage IV Lung Cancer
Inhatarget Therapeutics
2023-06-23 PHASE1; PHASE2
NCT05116462 ACTIVE_NOT_RECRUITING
Non-Small Cell Lung Cancer
Innovent Biologics (Suzhou) Co. Ltd.
2024-03-15 PHASE3
NCT05800574 RECRUITING
Oropharynx Cancer
Fox Chase Cancer Center
2023-03-14 PHASE2
NCT05543330 RECRUITING
Malignant Pleural Effusions; NSCLC Stage IV
Wuhan YZY Biopharma Co., Ltd.
2022-09-30 PHASE1; PHASE2
NCT05186974 ACTIVE_NOT_RECRUITING
Non-small Cell Lung Cancer
Gilead Sciences
2022-05-30 PHASE2
NCT04966663 RECRUITING
Non Small Cell Lung Cancer; Complete Surgical Resection; Circulating Tumor DNA
University Health Network, Toronto
2022-03-28 PHASE2
NCT05351788 RECRUITING
Non-small Cell Lung Cancer
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.
2022-05-20 PHASE2
NCT07225374 RECRUITING
Upper Tract Urothelial Carcinoma
Samsung Medical Center
2025-09-16 PHASE2
NCT07699185 RECRUITING
Esophageal Squamous Cell Carcinoma
Tongji Hospital
2024-01-29 PHASE2
NCT06511648 RECRUITING
Muscle-invasive Bladder Cancer
Spanish Oncology Genito-Urinary Group
2023-03-07 PHASE2
NCT06690476 RECRUITING
Esophageal Squamous Cell Carcinoma
Peking University
2024-10-10 EARLY_PHASE1
NCT05065957 RECRUITING
Biliary Tract Cancer
InnoPharmax Inc.
2022-03-29 PHASE2; PHASE3
NCT06911606 RECRUITING
SCLC, Limited Stage
Guangdong Provincial People's Hospital
2024-05-22 PHASE2
NCT05298423 COMPLETED
Carcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC
2022-05-03 PHASE3
NCT06143748 ACTIVE_NOT_RECRUITING
Esophagus Cancer
Sun Yat-sen University
2024-03-02 PHASE2
NCT04602377 RECRUITING
Small Cell Ovarian Carcinoma
ARCAGY/ GINECO GROUP
2021-08-04 PHASE2
NCT04015778 ACTIVE_NOT_RECRUITING
Non Small Cell Lung Cancer
Guangdong Association of Clinical Trials
2019-08-08 PHASE2
NCT04481204 WITHDRAWN
Borderline Resectable Pancreatic Adenocarcinoma; Locally Advanced Pancreatic Ductal Adenocarcinoma; Resectable Pancreatic Ductal Adenocarcinoma
M.D. Anderson Cancer Center
2023-04-18 PHASE2
NCT06897579 TERMINATED
Extensive Stage Small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2025-04-07 PHASE2
NCT06946901 RECRUITING
Hyperthermic Intraperitoneal Chemotherapy; Peritoneal Metastatic Pancreatic Cancer
Shanghai Zhongshan Hospital
2025-04-03 PHASE2
NCT04147351 COMPLETED
NSCLC Stage IIIB~IV
National Taiwan University Hospital
2020-04-10 PHASE2
NCT06916494 RECRUITING
Muscle Invasive Bladder Cancer
First Affiliated Hospital of Chongqing Medical University
2025-05-01 PHASE1
NCT06375915 UNKNOWN
Intrahepatic Cholangiocarcinoma
Francesco De Cobelli
2024-05-01 PHASE2
NCT06076837 TERMINATED
Pancreatic Cancer Metastatic; Pancreatic Adenocarcinoma Metastatic
HonorHealth Research Institute
2025-01-09 PHASE1
NCT04124198 ACTIVE_NOT_RECRUITING
Oropharynx Cancer; Oropharynx Squamous Cell Carcinoma; Carcinoma, Squamous Cell; Carcinoma; Oropharyngeal Neoplasms; Neoplasms, Squamous Cell; Neoplasms, Glandular and Epithelial; Neoplasms by Histologic Type; Pharyngeal Neoplasms Malignant and Unspecified; Otorhinolaryngologic Neoplasms; Head and Neck Neoplasms; Neoplasms by Site; Otorhinolaryngologic Diseases; Pharyngeal Diseases; Papillomavirus Infections; Virus Diseases; DNA Virus Infections; Tumor Virus Infections; Quality of Life
Christian von Buchwald
2019-03-01
NCT03582475 ACTIVE_NOT_RECRUITING
Bladder Small Cell Neuroendocrine Carcinoma; Castration-Resistant Prostate Carcinoma; Metastatic Bladder Urothelial Carcinoma; Metastatic Urethral Urothelial Carcinoma; Prostate Carcinoma Metastatic in the Bone; Prostate Neuroendocrine Neoplasm; Prostate Small Cell Carcinoma; Stage III Bladder Cancer American Joint Committee on Cancer ( AJCC) v8; Stage III Prostate Cancer AJCC v8; Stage III Urethral Cancer AJCC v8; Stage IV Bladder Cancer AJCC v8; Stage IV Prostate Cancer AJCC v8; Stage IV Urethral Cancer AJCC v8; Stage IVA Bladder Cancer AJCC v8; Stage IVB Bladder Cancer AJCC v8; Ureter Small Cell Carcinoma; Urothelial Carcinoma
Jonsson Comprehensive Cancer Center
2019-01-11 PHASE1
NCT02170090 ACTIVE_NOT_RECRUITING
Cholangiocarcinoma; Gall Bladder Carcinoma
Universitätsklinikum Hamburg-Eppendorf
2014-04 PHASE3
NCT06659042 RECRUITING
Lung Cancer, Non-Small Cell
Shanghai Chest Hospital
2024-11-20 PHASE2
NCT05527470 RECRUITING
Nasopharyngeal Carcinoma
Wei Jiang
2022-11-11 PHASE3
NCT06100497 RECRUITING
Head and Neck Squamous Cell Carcinoma
Beijing Tongren Hospital
2023-10-01 PHASE2
NCT04649385 COMPLETED
Advanced Solid Tumor
BeiGene
2021-03-04 PHASE1
NCT06588335 NOT_YET_RECRUITING
Esophageal Squamous Cell Carcinoma
Henan Provincial People's Hospital
2024-09-30 PHASE2
NCT06611137 RECRUITING
Laryngeal Cancer; Hypopharynx Cancer
Sun Yat-sen University
2024-09-11 PHASE2
NCT05430802 ACTIVE_NOT_RECRUITING
Non-small Cell Lung Cancer
Tang-Du Hospital
2022-02-24 PHASE2
NCT05813626 ACTIVE_NOT_RECRUITING
Nasopharyngeal Carcinoma
Zhejiang Cancer Hospital
2023-04-21 PHASE2
NCT01261728 COMPLETED
Urothelial Carcinoma
Memorial Sloan Kettering Cancer Center
2010-12-14 PHASE2
NCT04356170 COMPLETED
Cancer of Head and Neck
Groupe Oncologie Radiotherapie Tete et Cou
2021-02-04 PHASE2
NCT06048926 ENROLLING_BY_INVITATION
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital with Nanjing Medical University
2022-07-30
NCT05189028 UNKNOWN
Cervical Cancer; Neoadjuvant Chemotherapy
Chuangzhen Chen
2021-07-01 PHASE3
NCT02429687 RECRUITING
Ovarian Germ Cell Cancer; Ovarian Neoplasms; Ovarian Cancer
Beihua Kong
2015-04 PHASE3
NCT04898374 UNKNOWN
Nasopharyngeal Carcinoma
Kuwait Cancer Control Center
2021-05-01 PHASE3
NCT03088540 COMPLETED
Carcinoma,Non-Small-Cell Lung; Lung Carcinomas, Non-Small-Cell; Non-small-cell Lung Carcinoma; Nonsmall Cell Lung Cancer
Regeneron Pharmaceuticals
2017-05-29 PHASE3
NCT04832854 TERMINATED
Non-Small Cell Lung Cancer (NSCLC)
Hoffmann-La Roche
2021-04-23 PHASE2
NCT04222972 TERMINATED
RET-fusion Non Small Cell Lung Cancer; Lung Neoplasm; Carcinoma, Non-Small-Cell Lung; Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Disease; Carcinoma, Bronchogenic; Bronchial Diseases; Head and Neck Neoplasms; Adenocarcinoma; Carcinoma; Neoplasms by Histologic Type; Neoplasms, Germ Cell and Embryonal; Neoplasms, Nerve Tissue
Hoffmann-La Roche
2020-07-24 PHASE3
NCT04617756 RECRUITING
Urothelial Carcinoma; Cancer
Centre Hospitalier Universitaire de Nīmes
2021-09-29 PHASE2
NCT02595905 COMPLETED
Metastatic BRCA Hereditary Breast Carcinoma; Metastatic Breast Carcinoma; Metastatic Malignant Neoplasm in the Brain; Metastatic Triple-Negative Breast Carcinoma; Recurrent Breast Carcinoma; Stage IV Breast Cancer AJCC v6 and v7
National Cancer Institute (NCI)
2016-09-15 PHASE2
NCT05877911 UNKNOWN
Epithelial Ovarian Cancer; Acute Kidney Injury Due to Circulatory Failure
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
2023-05 PHASE2
NCT05312840 COMPLETED
Non Small Cell Lung Cancer
People's Hospital of Quzhou
2022-01-01 PHASE4
NCT05576272 UNKNOWN
Nasopharyngeal Carcinoma
Qilu Pharmaceutical Co., Ltd.
2022-05-19 PHASE2; PHASE3
NCT03875144 SUSPENDED
Peritoneal Mesothelioma; Peritoneal Carcinomatosis
Institut du Cancer de Montpellier - Val d'Aurelle
2020-09-10 PHASE2
NCT05991518 UNKNOWN
HER2 Gene Mutation
SUNHO(China)BioPharmaceutical CO., Ltd.
2023-04-25 PHASE1; PHASE2
NCT02969083 UNKNOWN
Upper Tract Urothelial Carcinoma
The European Uro-Oncology Group
2018-05-28 PHASE2
NCT06237257 UNKNOWN
Locally Advanced Cervical Cancer
Shanghai Shengdi Pharmaceutical Co., Ltd
2024-03-20 PHASE2
NCT04462965 UNKNOWN
Mucosal Melanoma
Peking University Cancer Hospital & Institute
2020-05-30 PHASE2
NCT05717790 RECRUITING
Nasopharyngeal Carcinoma by AJCC V8 Stage
Fourth Affiliated Hospital of Guangxi Medical University
2022-12-01
NCT02794571 COMPLETED
Advanced/Metastatic Tumors
Genentech, Inc.
2016-05-23 PHASE1
NCT06356155 Not yet recruiting
Urothelial Carcinoma
University of Michigan Rogel Cancer Center
2024-10 Phase 2
NCT03366415 UNKNOWN
Nasopharyngeal Carcinoma
Chaosu Hu
2018-01-01 PHASE3
NCT03107182 COMPLETED
HPV-Related Squamous Cell Carcinoma; HNSCC
University of Chicago
2017-06-27 PHASE2
NCT05701735 UNKNOWN
Locally Advanced Cervical Carcinoma
University of Santo Tomas Hospital, Philippines
2023-02-20
NCT06094296 TERMINATED
NSCLC
Bristol-Myers Squibb
2023-11-27 PHASE2
NCT05715840 UNKNOWN
Recurrent, or Metastatic Cervical Cancer With PD-L1 Positive (CPS≥1)
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
2023-01-31 PHASE3
NCT03765918 ACTIVE_NOT_RECRUITING
Head and Neck Neoplasms
Merck Sharp & Dohme LLC
2018-12-17 PHASE3
NCT02964013 COMPLETED
Neoplasms
Merck Sharp & Dohme LLC
2016-12-13 PHASE1
NCT07435311 COMPLETED
Head and Neck Squamous Cell Carcinoma
R-Pharm
2020-06-15 PHASE1
NCT03850067 COMPLETED
Small Cell Lung Carcinoma
Celgene
2019-03-12 PHASE1
NCT05433597 NOT_YET_RECRUITING
Nasopharyngeal Carcinoma; TNF; Chemo-radiotherapy
Sun Yat-sen University
2022-07-01 PHASE2; PHASE3
NCT03822897 ACTIVE_NOT_RECRUITING
Oropharyngeal Cancer
Canadian Cancer Trials Group
2019-06-28 PHASE2
NCT04383743 COMPLETED
Stage II Bladder Cancer AJCC v8; Stage IIIA Bladder Cancer AJCC v8; Muscle Invasive Bladder Carcinoma
University of Washington
2020-11-24 PHASE2
NCT04275713 COMPLETED
Cervical Cancer
Oslo University Hospital
2020-05-22 PHASE2
NCT00254384 COMPLETED
Recurrent Lung Non-Small Cell Carcinoma; Stage IA Lung Non-Small Cell Carcinoma AJCC v7; Stage IB Lung Non-Small Cell Carcinoma AJCC v7; Stage IIA Lung Non-Small Cell Carcinoma AJCC v7; Stage IIB Lung Non-Small Cell Carcinoma AJCC v7; Stage IIIA Lung Non-Small Cell Cancer AJCC v7; Stage IIIB Lung Non-Small Cell Cancer AJCC v7
M.D. Anderson Cancer Center
2005-10-05 PHASE1
NCT04456322 ACTIVE_NOT_RECRUITING
Nasopharyngeal Carcinoma
Sun Yat-sen University
2020-08-17 PHASE3
NCT06393816 Not yet recruiting
Large Cell Neuroendocrine Carcinoma of the Lung
Centre Leon Berard|Groupe Français de Pneumo-Cancérologie
2024-05 Phase 2
NCT06406465 Not yet recruiting
Carcinoma Neuroendocrine|Tumor Neuroendocrine|Tumors Neuroendocrine|Neuroendocrine; Carcinoma|Small Cell; Receptors
National Cancer Institute (NCI)|National Institutes of Health Clinical Center (CC)
2024-05-15 Phase 2
NCT04915183 Recruiting
Hearing Loss|Head and Neck Cancer
National Institute on Deafness and Other Communication Disorders (NIDCD)|National Institutes of Health Clinical Center (CC)
2024-05-15 Phase 2
NCT04619797 COMPLETED
Non-small Cell Lung Cancer (NSCLC)
Hoffmann-La Roche
2020-12-15 PHASE2; PHASE3
NCT04203160 TERMINATED
Biliary Tract Cancer
University of Michigan Rogel Cancer Center
2020-06-23 PHASE1; PHASE2
NCT04526691 ACTIVE_NOT_RECRUITING
Advanced or Metastatic NSCLC
Daiichi Sankyo
2020-09-15 PHASE1
NCT03615326 COMPLETED
Gastric Neoplasms; Gastroesophageal Junction Adenocarcinoma
Merck Sharp & Dohme LLC
2018-10-05 PHASE3
NCT04524689 TERMINATED
Non-squamous Non-small-cell Lung Cancer (NSQ NSCLC)
Sanofi
2020-10-26 PHASE2
NCT05947201 UNKNOWN
The Efficacy and Safety of Therapy Efficacy for Locally Advanced ESCC
Weijia Fang, MD
2023-05-08 PHASE2
NCT02885974 COMPLETED
Bladder Cancer
Baylor College of Medicine
2016-12 PHASE1
NCT03612791 COMPLETED
Locally Advanced Cervical Cancer
Gustave Roussy, Cancer Campus, Grand Paris
2018-08-13 PHASE2
NCT04882241 COMPLETED
Gastric Cancer; Gastroesophageal Junction Cancer
Merck Sharp & Dohme LLC
2020-07-29 PHASE3
NCT04951115 TERMINATED
Small-cell Lung Cancer
Weill Medical College of Cornell University
2021-07-12 PHASE2
NCT04890522 NOT_YET_RECRUITING
Nasopharyngeal Carcinoma; Metastasis; Chemotherapy; Immunotherapy; Survival
Sun Yat-sen University
2021-07-01 PHASE2; PHASE3
NCT05386888 COMPLETED
NSCLC, Stage III
Genfleet Therapeutics (Shanghai) Inc.
2022-09-09 PHASE2
NCT00980954 COMPLETED
Cervical Cancer
Radiation Therapy Oncology Group
2009-09 PHASE3
NCT05151549 UNKNOWN
Cervical Cancer
Hunan Cancer Hospital
2021-12-01 PHASE2
NCT04871529 TERMINATED
Bladder Carcinoma Infiltrating the Muscle of the Bladder Wall; Infiltrating Renal Pelvis and Ureter Urothelial Carcinoma; Stage II Bladder Cancer AJCC v8
SWOG Cancer Research Network
2022-08-10 PHASE2
NCT02501954 COMPLETED
Endometrial Clear Cell Adenocarcinoma; Endometrial Serous Adenocarcinoma; Stage IIIA Uterine Corpus Cancer; Stage IIIB Uterine Corpus Cancer; Stage IIIC Uterine Corpus Cancer; Stage IVA Uterine Corpus Cancer
Women's Cancer Care Associates, LLC
2015-03 PHASE3
NCT05030077 UNKNOWN
Urothelial Carcinoma; Anlotinib; Urogenital Neoplasms; Cisplatin; Carboplatin; Gemcitabine; Antineoplastic Agents
Tianjin Medical University Second Hospital
2021-10-01 PHASE2
NCT04870112 TERMINATED
Non-Small Cell Lung Cancer; Small Cell Lung Cancer
AstraZeneca
2021-06-28 PHASE1
NCT03141359 ACTIVE_NOT_RECRUITING
Lung Cancer Stage II; Lung Cancer Stage III; Non Small Cell Lung Cancer
Wake Forest University Health Sciences
2017-05-12 PHASE2
NCT05449483 UNKNOWN
Esophageal Squamous Cell Carcinoma by AJCC V8 Stage; Unresectable
Tianjin Medical University Cancer Institute and Hospital
2022-05-11 PHASE2
NCT04712903 COMPLETED
Small Cell Lung Carcinoma Extensive Disease
AstraZeneca
2020-12-16 PHASE3
NCT04840290 UNKNOWN
Non Small Cell Lung Cancer
Tang-Du Hospital
2019-06-01 PHASE3
NCT04226456 TERMINATED
Ototoxic Hearing Loss; Ototoxic Hearing Loss, Bilateral; Ototoxicity; Tinnitus
Centre Hospitalier Universitaire Saint Pierre
2021-07-10 PHASE4
NCT03260712 COMPLETED
Biliary Tract Cancer; Metastatic Cancer; Advanced Cancer; Gallbladder Cancer
European Organisation for Research and Treatment of Cancer - EORTC
2020-01-07 PHASE2
NCT04005716 COMPLETED
Small Cell Lung Cancer
BeiGene
2019-07-22 PHASE3
NCT04814069 UNKNOWN
Head and Neck Cancer; Radiation; PD-1
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
2021-04-01 PHASE2
NCT06105619 ACTIVE_NOT_RECRUITING
Glioblastoma
Beijing Pearl Biotechnology Limited Liability Company
2018-10-08 PHASE2; PHASE3
NCT04846634 NOT_YET_RECRUITING
Resectable Locally Advanced Non-small Cell Lung Cancer
Tianjin Medical University Cancer Institute and Hospital
2021-08 PHASE2
NCT02167711 COMPLETED
Cholangio Carcinoma
Chinese University of Hong Kong
2014-09-17 PHASE2
NCT04672330 COMPLETED
Neoadjuvant Immunotherapy of Cisplatin-ineligible High Risk Upper Urinary Tract Urothelial Carcinoma
RenJi Hospital
2020-12-01 PHASE2
NCT02120807 COMPLETED
Stage IV Lung Adenocarcinoma
Memorial Sloan Kettering Cancer Center
2014-04-15 PHASE1
NCT03515837 COMPLETED
Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC
2018-06-29 PHASE3
NCT03251313 UNKNOWN
Triple Negative Breast Cancer
Fudan University
2019-05-15 PHASE1
NCT02629718 UNKNOWN
PFS; OS; Quality of Life
Sun Yat-sen University
2015-12 PHASE3
NCT02610010 UNKNOWN
Nasopharyngeal Carcinoma
Sun Yat-sen University
2015-11 PHASE3
NCT03535727 COMPLETED
Adenocarcinoma; Pancreatic Neoplasms; Neoplasm, Glandular; Neoplasms; Neoplasms Pancreatic; Digestive System Neoplasm; Endocrine Gland Neoplasms; Digestive System Disease; Pancreatic Diseases; Endocrine System Diseases
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2018-06-21 PHASE1; PHASE2
NCT03228537 ACTIVE_NOT_RECRUITING
Biphasic Mesothelioma; Epithelioid Mesothelioma; Stage I Pleural Diffuse Malignant Mesothelioma AJCC v7; Stage IA Pleural Diffuse Malignant Mesothelioma AJCC v7; Stage IB Pleural Diffuse Malignant Mesothelioma AJCC v7; Stage II Pleural Diffuse Malignant Mesothelioma AJCC v7; Stage III Pleural Diffuse Malignant Mesothelioma AJCC v7
National Cancer Institute (NCI)
2018-07-16 PHASE1
NCT04861948 TERMINATED
Solid Tumors; Lung Adenocarcinoma; Osteosarcoma
Innovent Biologics (Suzhou) Co. Ltd.
2021-05-25 PHASE1
NCT03992911 UNKNOWN
Neuroendocrine Carcinoma of the Bladder
Peking University
2019-06-19 PHASE2; PHASE3
NCT04551950 COMPLETED
Cervical Cancer
EMD Serono Research & Development Institute, Inc.
2020-10-19 PHASE1
NCT04390958 UNKNOWN
Esophageal Squamous Cell Carcinoma
Chinese Academy of Medical Sciences
2020-05-15 PHASE2
NCT04414566 UNKNOWN
Nasopharyngeal Carcinoma
West China Hospital
2020-06-01 PHASE3
NCT03935347 WITHDRAWN
Metastatic Bladder Urothelial Carcinoma; Metastatic Renal Pelvis Urothelial Carcinoma; Metastatic Ureter Urothelial Carcinoma; Metastatic Urethral Urothelial Carcinoma; Unresectable Renal Pelvis Urothelial Carcinoma; Unresectable Ureter Urothelial Carcinoma
Roswell Park Cancer Institute
2019-06-20 PHASE2
NCT02296684 COMPLETED
Cancer of Head and Neck; Head and Neck Cancer; Neoplasms, Head and Neck; Carcinoma, Squamous Cell of Head and Neck; Squamous Cell Carcinoma of the Head and Neck; Squamous Cell Carcinoma, Head and Neck
Washington University School of Medicine
2015-03-25 PHASE2
NCT04480190 WITHDRAWN
Cholangiocarcinoma; Biliary Cancer
Jordan Kharofa
2021-02-04 PHASE1
NCT03737123 TERMINATED
Urothelial Carcinoma
Nabil Adra
2018-12-19 PHASE2
NCT04063683 UNKNOWN
Esophageal Squamous Cell Carcinoma
Henan Cancer Hospital
2019-10-07 PHASE2
NCT03785925 COMPLETED
Urinary Bladder Neoplasm; Neoplasm Metastasis
Nektar Therapeutics
2019-04-29 PHASE2
NCT02268695 COMPLETED
Head and Neck Squamous Cell Carcinoma
Groupe Oncologie Radiotherapie Tete et Cou
2014-10-10 PHASE2
NCT04470076 UNKNOWN
Non Small Cell Lung Cancer; Surgery; EGFR Activating Mutation; Chemotherapy; EGFR TKI
Fifth Affiliated Hospital, Sun Yat-Sen University
2020-07-10 PHASE2
NCT03644589 WITHDRAWN
Estrogen Receptor Negative; HER2/Neu Negative; Metastatic Breast Cancer; Progesterone Receptor Negative; Recurrent Breast Carcinoma; Triple Negative Breast Cancer
University of Washington
2019-04-01 PHASE2
NCT00370890 COMPLETED
Nasopharyngeal Cancer
Chinese University of Hong Kong
2006-09-04 PHASE3
NCT02611037 COMPLETED
Malignant Pleural Mesothelioma; Mesothelioma
H. Lee Moffitt Cancer Center and Research Institute
2016-03-04 PHASE2
NCT02940925 COMPLETED
Nasopharyngeal Carcinoma
Sun Yat-sen University
2016-10-20 PHASE3
NCT03707509 UNKNOWN
Nasopharyngeal Carcinoma
Jiangsu HengRui Medicine Co., Ltd.
2018-11-13 PHASE3
NCT03612219 UNKNOWN
Nasopharyngeal Carcinoma
Wei Jiang
2018-07-01 PHASE2
NCT03473756 COMPLETED
Urothelial Carcinoma
Bayer
2018-05-15 PHASE1
NCT02949700 COMPLETED
Head and Neck Squamous Cell Carcinoma
Baylor College of Medicine
2017-01-26 PHASE1; PHASE2
NCT02550327 COMPLETED
Pancreatic Adenocarcinoma
Baylor Research Institute
2016-01 EARLY_PHASE1
NCT03684811 COMPLETED
Cohort 1a and 1b: Glioma (Advanced Gliomas and Glioblastoma Multiforme); Cohort 2a and 2b: Hepatobiliary Tumors (Hepatocellular Carcinoma, Bile Duct Carcinoma, Intrahepatic Cholangiocarcinoma, Other Hepatobiliary Carcinomas); Cohort 3a and 3b: Chondrosarcoma; Cohort 4a and 4b: Intrahepatic Cholangiocarcinoma; Cohort 5a: Other Non-Central Nervous System Solid Tumors With IDH1 Mutations
Forma Therapeutics, Inc.
2018-11-01 PHASE1; PHASE2
NCT04066491 TERMINATED
Biliary Tract Cancer; Cholangiocarcinoma; Gallbladder Cancer
EMD Serono Research & Development Institute, Inc.
2019-09-20 PHASE2; PHASE3
NCT04473716 COMPLETED
Oral Cancer; Induction Chemotherapy; Programmed Cell Death 1 Inhibitor; Inductive Therapy
Shanghai Jiao Tong University School of Medicine
2020-07-30 PHASE1
NCT02445391 ACTIVE_NOT_RECRUITING
Estrogen Receptor Negative; HER2/Neu Negative; Invasive Breast Carcinoma; Progesterone Receptor Negative; Stage II Breast Cancer; Stage IIA Breast Cancer; Stage IIB Breast Cancer; Stage III Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer; Triple-Negative Breast Carcinoma
ECOG-ACRIN Cancer Research Group
2015-10-20 PHASE3
NCT02567383 UNKNOWN
Recurrent Head and Neck Cancer
Shin Kong Wu Ho-Su Memorial Hospital
2015-09 PHASE2
NCT01004978 COMPLETED
Hepatocellular Carcinoma; Unresectable Hepatocellular Carcinoma
National Cancer Institute (NCI)
2009-10-28 PHASE3
NCT03171493 COMPLETED
Urothelial Carcinoma
Vyriad, Inc.
2018-07-20 PHASE1
NCT04054362 COMPLETED
Pancreatic Cancer
Barts & The London NHS Trust
2018-11-29 PHASE2
NCT03901378 WITHDRAWN
Neuroendocrine Carcinoma; Large Cell Neuroendocrine Carcinoma of the Lung; High Grade Neuroendocrine Carcinoma, Any Site
Ochsner Health System
2019-10-02 PHASE2
NCT02723864 COMPLETED
Neoplasms
National Cancer Institute (NCI)
2017-08-09 PHASE1
NCT03366766 TERMINATED
Non-Squamous Non-Small Cell Lung Carcinoma; Stage I Non-Small Cell Lung Cancer; Stage IA Non-Small Cell Lung Carcinoma; Stage IB Non-Small Cell Lung Carcinoma; Stage II Non-Small Cell Lung Cancer; Stage IIA Non-Small Cell Lung Carcinoma; Stage IIB Non-Small Cell Lung Carcinoma; Stage IIIA Non-Small Cell Lung Cancer
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
2017-12-20 PHASE2
NCT04750382 UNKNOWN
Triple-negative Breast Cancer
Taizhou Hanzhong biomedical co. LTD
2019-07-15 PHASE1; PHASE2
NCT02001168 UNKNOWN
Non-small Cell Lung Cancer
Xinjiang Medical University
2013-10 PHASE3
NCT02627807 UNKNOWN
Nasopharyngeal Neoplasms
Sun Yat-sen University
2015-12
NCT03781869 UNKNOWN
Extensive-stage Small Cell Lung Cancer
Third Military Medical University
2018-12 PHASE2
NCT02862457 COMPLETED
Neoplasms; Carcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC
2016-08-23 PHASE1
NCT03717155 COMPLETED
Squamous Non-Small Cell Lung Cancer
Merck KGaA, Darmstadt, Germany
2018-10-30 PHASE2
NCT01595061 UNKNOWN
Stage III Vulvar Cancer AJCC v7; Stage IIIA Vulvar Cancer AJCC v7; Stage IIIB Vulvar Cancer AJCC v7; Stage IIIC Vulvar Cancer AJCC v7; Stage IVA Vulvar Cancer AJCC v7; Vulvar Squamous Cell Carcinoma
Gynecologic Oncology Group
2012-07-02 PHASE2
NCT02392637 COMPLETED
Stage III Intrahepatic Cholangiocarcinoma AJCC v7; Stage IIIA Gallbladder Cancer AJCC v7; Stage IIIB Gallbladder Cancer AJCC v7; Stage IVA Gallbladder Cancer AJCC v7; Stage IVA Intrahepatic Cholangiocarcinoma AJCC v7; Stage IVB Gallbladder Cancer AJCC v7; Stage IVB Intrahepatic Cholangiocarcinoma AJCC v7; Unresectable Extrahepatic Bile Duct Carcinoma; Unresectable Gallbladder Carcinoma
M.D. Anderson Cancer Center
2015-04-02 PHASE2
NCT03601975 UNKNOWN
Nasopharyngeal Carcinoma
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2018-08-27 PHASE3
NCT03912402 UNKNOWN
Cervical Cancer; Cervical Cancer Metastatic; Cervical Cancer Recurrent
Biocad
2018-12-25 PHASE2
NCT03189719 COMPLETED
Esophageal Neoplasms
Merck Sharp & Dohme LLC
2017-07-25 PHASE3
NCT04251689 COMPLETED
Cis-Platinum Nephropathy; Mannitol Adverse Reaction
Phramongkutklao College of Medicine and Hospital
2018-12-01 PHASE2; PHASE3
NCT02879513 UNKNOWN
Invasive Ductal Breast Cancer; Tubular Breast Cancer; Mucinous Breast Cancer; Inflammatory Breast Cancer
RenJi Hospital
2014-01 PHASE3
NCT00158678 COMPLETED
Oral Cancer; Oropharynx Cancer; Hypopharynx Cancer
Groupe Oncologie Radiotherapie Tete et Cou
2005-09-27 PHASE3
NCT03193853 COMPLETED
Triple Negative Breast Cancer
Joyce O'Shaughnessy
2017-07-18 PHASE2
NCT02363829 COMPLETED
Uterine Cervix Cancer
Abramson Cancer Center at Penn Medicine
2015-02 PHASE1
NCT02610556 UNKNOWN
Nasopharyngeal Carcinoma
Sun Yat-sen University
2016-01 PHASE2
NCT02113878 COMPLETED
Carcinoma, Squamous Cell of Head and Neck; HPV Positive Oropharyngeal Squamous Cell Carcinoma; Hypopharyngeal Cancer; Early Invasive Cervical Squamous Cell Carcinoma; Carcinoma of Larynx; Cancer of Nasopharynx
Dana-Farber Cancer Institute
2014-09-29 PHASE1
NCT02858804 COMPLETED
Mantle Cell Lymphoma
Institute of Hematology & Blood Diseases Hospital, China
2016-01 PHASE4
NCT03617913 COMPLETED
Bladder Carcinoma Infiltrating the Muscle of the Bladder Wall; Stage II Bladder Cancer AJCC v8; Stage II Renal Pelvis Cancer AJCC v8; Stage II Ureter Cancer AJCC v8; Stage II Urethral Cancer AJCC v8; Stage III Bladder Cancer AJCC v8; Stage III Renal Pelvis Cancer AJCC v8; Stage III Ureter Cancer AJCC v8; Stage III Urethral Cancer AJCC v8; Stage IIIA Bladder Cancer AJCC v8; Stage IIIB Bladder Cancer AJCC v8; Urethral Urothelial Carcinoma
Mayo Clinic
2018-09-19 PHASE2
NCT03502148 COMPLETED
Oral Squamous Cell Carcinoma
Privo Technologies
2018-06-19 PHASE1; PHASE2
NCT03515538 COMPLETED
Oral Mucositis
EpicentRx, Inc.
2018-07-12 PHASE2
NCT03269162 UNKNOWN
NSCLC
lihegen
2016-09-30 PHASE3
NCT00039338 UNKNOWN
Cervical Cancer
European Organisation for Research and Treatment of Cancer - EORTC
2002-03 PHASE3
NCT00392327 COMPLETED
Anaplastic Medulloblastoma; Medulloblastoma
Children's Oncology Group
2007-05-23 PHASE3
NCT01743365 COMPLETED
Gastric Cancer; Gastroesophageal Junction Cancer
Hellenic Cooperative Oncology Group
2013-02-11 PHASE2
NCT02585973 COMPLETED
Carcinoma, Squamous Cell of Head and Neck
UNC Lineberger Comprehensive Cancer Center
2015-10-26 PHASE1
NCT02878889 UNKNOWN
Nasopharyngeal Carcinoma
Zhejiang Cancer Hospital
2016-08 PHASE2
NCT02819999 TERMINATED
Small Cell Lung Cancer
AbbVie
2016-10 PHASE1
NCT03950674 COMPLETED
Non-Small-Cell Lung Carcinoma
Merck Sharp & Dohme LLC
2016-02-22 PHASE3
NCT03469557 COMPLETED
Esophageal Squamous Cell Carcinoma, Gastric Carcinoma, Gastroesophageal Junction Carcinoma
BeiGene
2017-07-18 PHASE2
NCT01309633 COMPLETED
Nasopharyngeal Carcinoma
National University Hospital, Singapore
2011-09-02 PHASE2
NCT01077427 UNKNOWN
Resected Pancreatic Adenocarcinoma
Klinikum der Universitaet Muenchen, Grosshadern
2012-03 PHASE3
NCT02726399 TERMINATED
Gastric Cancer; Gastroesophageal Junction Cancer
Memorial Sloan Kettering Cancer Center
2016-03-18 PHASE2
NCT03432598 COMPLETED
Locally Advanced Lung Cancer; Metastatic Lung Cancer
BeiGene
2017-08-24 PHASE2
NCT02322593 COMPLETED
Gastric Cancer
Taiho Pharmaceutical Co., Ltd.
2014-12 PHASE3
NCT03167177 WITHDRAWN
Melanoma
ImmunityBio, Inc.
2017-12 PHASE1; PHASE2
NCT03061058 UNKNOWN
Stomach Neoplasms; Chemotherapy Effect; Chemotherapeutic Toxicity
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
2013-04-01 PHASE3
NCT02429037 UNKNOWN
Advanced Head and Neck Cancer
Shenzhen SiBiono GeneTech Co.,Ltd
2015-05 PHASE2
NCT01933568 COMPLETED
Inoperable Locally Advanced Non Small Cell Lung Cancer
The Netherlands Cancer Institute
2013-02-28 PHASE1
NCT01872962 UNKNOWN
Nasopharyngeal Carcinoma
Sun Yat-sen University
2013-11 PHASE3
NCT02281708 UNKNOWN
Stage Ib Lung Carcinoma
Seoul National University Hospital
2014-10 PHASE3
NCT03574649 WITHDRAWN
Non Small Cell Lung Cancer
ImmunityBio, Inc.
2018-06 PHASE2
NCT01589094 COMPLETED
Bladder Cancer
Memorial Sloan Kettering Cancer Center
2012-04 PHASE2
NCT02375880 COMPLETED
Carcinoma of Intrahepatic and Extra-hepatic Biliary System; Carcinoma of Gallbladder; Bile Duct Cancer; Cholangiocarcinoma
Leap Therapeutics, Inc.
2015-06 PHASE1
NCT02504229 UNKNOWN
Gastric Cancer
Beijing Biohealthcare Biotechnology Co.,Ltd
2014-11 PHASE2
NCT02485548 UNKNOWN
Head and Neck Squamous Cell Cancer
Jiangsu Cancer Institute & Hospital
2015-06 PHASE3
NCT02263105 COMPLETED
High-grade Gliomas
Huashan Hospital
2014-10 PHASE2
NCT02508246 COMPLETED
Head and Neck Squamous Cell Carcinoma
University of Washington
2015-07-22 PHASE1
NCT01275612 WITHDRAWN
Solid Tumors; Acute Kidney Injury
Mario Negri Institute for Pharmacological Research
2010-11 PHASE1
NCT02607631 COMPLETED
Thymic Epithelial Tumors
Samsung Medical Center
2015-11 PHASE2
NCT00997906 UNKNOWN
Head and Neck Cancer
National Cancer Centre, Singapore
2009-09-15 PHASE2; PHASE3
NCT03427359 COMPLETED
Nasopharyngeal Carcinoma
The University of Hong Kong-Shenzhen Hospital
2015-01-22 PHASE2
NCT02409355 TERMINATED
Non-Small Cell Lung Cancer
Hoffmann-La Roche
2015-05-07 PHASE3
NCT07671495 COMPLETED
Melanoma Stage I; Melanoma Stage III; Melanoma Stage II; Skin Melanoma
MIPO Clinic
2014-01 PHASE2
NCT01301612 WITHDRAWN
Carcinoma; Adenocarcinoma; Uterine Cervix Adenosquamous Carcinoma
Eurofarma Laboratorios S.A.
2011-01 PHASE2
NCT02513355 UNKNOWN
Non-small Cell Lung Cancer
Nanjing NingQi Medicine Science and Technology Co., Ltd.
2015-02 PHASE4
NCT02344095 COMPLETED
Epithelial Ovarian Carcinoma; Fallopian Tube Carcinoma; Primary Peritoneal Carcinoma
Seoul National University Hospital
2014-12 PHASE1
NCT02051868 UNKNOWN
Squamous Cell Carcinoma of the Anus
Royal Marsden NHS Foundation Trust
2013-12 PHASE2
NCT01524991 COMPLETED
Urothelial Carcinoma
Hoosier Cancer Research Network
2012-01 PHASE2
NCT01215136 TERMINATED
Transitional Cell Carcinoma; Bladder Carcinoma; Urothelial Carcinoma
Matthew Galsky
2010-12 PHASE2
NCT00828386 TERMINATED
Nasopharyngeal Cancers
Groupe Oncologie Radiotherapie Tete et Cou
2009-01 PHASE3
NCT02326285 TERMINATED
Non-squamous Non-small Cell Lung Cancer Stage II; Non-squamous Non-small Cell Lung Cancer Stage IIIA; Non-squamous Non-small Cell Lung Cancer Stage IIIB; Activating EGFR Mutation; NSCLC
AIO-Studien-gGmbH
2015-11 PHASE2; PHASE3
NCT02801487 TERMINATED
Nasopharyngeal Carcinoma
Shanghai Proton and Heavy Ion Center
2015-09 PHASE1; PHASE2
NCT02223611 UNKNOWN
Non-small Cell Lung Cancer Stage Ⅱ; Non-small Cell Lung Cancer Stage ⅢA
Hebei Medical University Fourth Hospital
2014-12 PHASE2
NCT02208583 UNKNOWN
Hormone Refractory Prostate Cancer
Tianjin Medical University Cancer Institute and Hospital
2014-06
NCT00117572 COMPLETED
Cancer of the Pharynx; Cancer of the Larynx; Cancer of the Nasal Cavity; Paranasal Sinus Neoplasms; Cancer of the Oral Cavity
University of Chicago
2004-11 PHASE3
NCT01326468 WITHDRAWN
Head and Neck Cancer
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
2011-12-08
NCT03117335 COMPLETED
Advanced Non-small Cell Lung Cancer
Jiangsu Wuzhong Pharmaceutical Group Co., Ltd.
2011-11-10 PHASE3
NCT02088515 COMPLETED
Squamous Cell Carcinoma
Jiangsu Simcere Pharmaceutical Co., Ltd.
2013-12 PHASE4
NCT00575952 COMPLETED
Endometrial Adenosquamous Carcinoma; Endometrial Clear Cell Adenocarcinoma; Endometrial Mixed Adenocarcinoma; Endometrial Serous Adenocarcinoma; Endometrial Squamous Cell Carcinoma; Endometrial Undifferentiated Carcinoma; Recurrent Uterine Corpus Carcinoma; Stage IIIA Uterine Corpus Cancer; Stage IIIC Uterine Corpus Cancer; Stage IVA Uterine Corpus Cancer; Stage IVB Uterine Corpus Cancer
Gynecologic Oncology Group
2008-01-17 PHASE1
NCT01846390 COMPLETED
Peripheral T-Cell Lymphoma; Diffuse Large B-Cell Lymphoma
Canadian Cancer Trials Group
2013-10-01 PHASE1
NCT01887340 UNKNOWN
Seminoma
Gustave Roussy, Cancer Campus, Grand Paris
2013-06 PHASE2
NCT01216111 COMPLETED
Triple Negative Breast Cancer
Fudan University
2011-01-01 PHASE3
NCT01182168 COMPLETED
Bladder Cancer; Renal Pelvis Cancer; Ureter Cancer
Memorial Sloan Kettering Cancer Center
2010-08 PHASE1
NCT01641172 COMPLETED
Testicular Cancer
University Medical Center Groningen
2012-06 PHASE4
NCT01501149 UNKNOWN
Nasal and Nasal-type NK/T-cell Lymphoma
Mingzhi Zhang
2011-01 PHASE4
NCT02016274 UNKNOWN
Esophageal Squamous Cell Cancer
Shen Lin
2013-12 PHASE2
NCT01191892 COMPLETED
Bladder Cancer; Transitional Cell Cancer of the Renal Pelvis and Ureter; Ureter Cancer; Urethral Cancer
Cardiff University
2010-06 PHASE2
NCT01496742 COMPLETED
Non-Squamous Non-Small Cell Lung Cancer
Genentech, Inc.
2012-04 PHASE2
NCT00324805 COMPLETED
Stage IB Lung Non-Small Cell Carcinoma AJCC v7; Stage IIA Lung Non-Small Cell Carcinoma AJCC v7; Stage IIB Lung Non-Small Cell Carcinoma AJCC v7; Stage IIIA Lung Non-Small Cell Cancer AJCC v7
National Cancer Institute (NCI)
2007-07-19 PHASE3
NCT01928680 UNKNOWN
Metastatic Breast Cancer
Chinese Academy of Medical Sciences
2012-11 PHASE2
NCT01728480 WITHDRAWN
Mucositis; Recurrent Squamous Cell Carcinoma of the Hypopharynx; Recurrent Squamous Cell Carcinoma of the Larynx; Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity; Recurrent Squamous Cell Carcinoma of the Nasopharynx; Recurrent Squamous Cell Carcinoma of the Oropharynx; Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Recurrent Verrucous Carcinoma of the Larynx; Recurrent Verrucous Carcinoma of the Oral Cavity; Stage III Squamous Cell Carcinoma of the Hypopharynx; Stage III Squamous Cell Carcinoma of the Larynx; Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage III Squamous Cell Carcinoma of the Nasopharynx; Stage III Squamous Cell Carcinoma of the Oropharynx; Stage III Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage III Verrucous Carcinoma of the Larynx; Stage III Verrucous Carcinoma of the Oral Cavity; Stage IV Squamous Cell Carcinoma of the Hypopharynx; Stage IV Squamous Cell Carcinoma of the Nasopharynx; Stage IVA Squamous Cell Carcinoma of the Larynx; Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVA Squamous Cell Carcinoma of the Oropharynx; Stage IVA Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage IVA Verrucous Carcinoma of the Larynx; Stage IVA Verrucous Carcinoma of the Oral Cavity; Stage IVB Squamous Cell Carcinoma of the Larynx; Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVB Squamous Cell Carcinoma of the Oropharynx; Stage IVB Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage IVB Verrucous Carcinoma of the Larynx; Stage IVB Verrucous Carcinoma of the Oral Cavity; Stage IVC Squamous Cell Carcinoma of the Larynx; Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVC Squamous Cell Carcinoma of the Oropharynx; Stage IVC Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Stage IVC Verrucous Carcinoma of the Larynx; Stage IVC Verrucous Carcinoma of the Oral Cavity; Tongue Cancer
Roswell Park Cancer Institute
2014-01 PHASE1
NCT01936974 TERMINATED
Ovarian Carcinoma; Fallopian Tube Carcinoma; Peritoneal Carcinoma
Western Regional Medical Center
2013-09 PHASE2
NCT02216617 COMPLETED
HNSCC
Groupe Oncologie Radiotherapie Tete et Cou
2014-08-06 PHASE1
NCT01616849 COMPLETED
Stage IV Nasopharyngeal Carcinoma
Sun Yat-sen University
2012-05 PHASE2
NCT02001896 UNKNOWN
Non-Small Cell Lung Cancer
Xinjiang Medical University
2013-12 PHASE3
NCT01487915 UNKNOWN
Advanced Urothelial Carcinoma
Asan Medical Center
2010-10 PHASE2
NCT02030574 TERMINATED
Invasive Bladder Cancer; Bladder Cancer
Brown University
2014-07 PHASE2
NCT00820248 COMPLETED
Head and Neck Cancer
NCIC Clinical Trials Group
2008-12-30 PHASE3
NCT01126749 TERMINATED
Bladder Cancer
Eisai Inc.
2010-04-16 PHASE1; PHASE2
NCT00252161 COMPLETED
Gastric Neoplasm
Haruhiko Fukuda
2005-11 PHASE3
NCT01450761 COMPLETED
Small Cell Lung Carcinoma
Bristol-Myers Squibb
2011-12-13 PHASE3
NCT00677118 UNKNOWN
Nasopharyngeal Carcinoma
Sun Yat-sen University
2006-06 PHASE3
NCT01029678 COMPLETED
Non Small Cell Lung Cancer
University Hospital, Limoges
2010-01 PHASE2
NCT01487226 UNKNOWN
Cervical Cancer
Korean Gynecologic Oncology Group
2008-01 PHASE2
NCT00274937 COMPLETED
Stage I Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7; Stage I Nasopharyngeal Undifferentiated Carcinoma AJCC v7; Stage II Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7; Stage II Nasopharyngeal Undifferentiated Carcinoma AJCC v7; Stage III Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7; Stage III Nasopharyngeal Undifferentiated Carcinoma AJCC v7; Stage IV Nasopharyngeal Keratinizing Squamous Cell Carcinoma AJCC v7; Stage IV Nasopharyngeal Undifferentiated Carcinoma AJCC v7
Children's Oncology Group
2006-02-20 PHASE3
NCT01204307 COMPLETED
Advanced Non-Squamous Non-Small Cell Lung Cancer
Chang Gung Memorial Hospital
2010-01 PHASE2
NCT02107235 COMPLETED
Head and Neck Neoplasms; Carcinoma, Squamous Cell
Traws Pharma, Inc.
2014-01 PHASE1
NCT01860040 TERMINATED
Non-squamous Cell Non-Metastatic Non-Small Cell Lung Cancer; Squamous Cell Non-Metastatic Non-Small Cell Lung Cancer
Western Regional Medical Center
2013-04 PHASE2
NCT00721513 COMPLETED
Head and Neck Cancer
Wake Forest University Health Sciences
2008-09 PHASE2
NCT01614938 UNKNOWN
Nasopharyngeal Carcinoma
Fudan University
2010-08 PHASE2
NCT01502202 UNKNOWN
Non Small Cell Lung Cancer; Adenocarcinoma
National Cancer Center, Korea
2012-03 PHASE2
NCT00949949 COMPLETED
Cholangiocarcinoma of the Gallbladder; Localized Gallbladder Cancer; Unresectable Gallbladder Cancer; Unspecified Adult Solid Tumor, Protocol Specific
Mayo Clinic
2009-09 PHASE1
NCT01947062 UNKNOWN
Lung Cancer; Squamous Cell Carcinoma of the Lung; Locally Advanced and Metastatic Squamous Cell Carcinoma of the Lung
Swami Rama Cancer Hospital and Research Institute
2013-10 PHASE3
NCT01467115 COMPLETED
Head and Neck Cancer
Drexel University College of Medicine
2010-03 PHASE2
NCT01275664 TERMINATED
Nausea and Vomiting; Ovarian Brenner Tumor; Ovarian Clear Cell Cystadenocarcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mucinous Cystadenocarcinoma; Ovarian Seromucinous Carcinoma; Ovarian Serous Cystadenocarcinoma; Stage II Ovarian Cancer; Stage IIA Fallopian Tube Cancer; Stage IIA Ovarian Cancer; Stage IIB Fallopian Tube Cancer; Stage IIB Ovarian Cancer; Stage IIC Fallopian Tube Cancer; Stage IIC Ovarian Cancer; Stage IIIA Fallopian Tube Cancer; Stage IIIA Ovarian Cancer; Stage IIIA Primary Peritoneal Cancer; Stage IIIB Fallopian Tube Cancer; Stage IIIB Ovarian Cancer; Stage IIIB Primary Peritoneal Cancer; Stage IIIC Fallopian Tube Cancer; Stage IIIC Ovarian Cancer; Stage IIIC Primary Peritoneal Cancer; Stage IV Fallopian Tube Cancer; Stage IV Ovarian Cancer; Stage IV Primary Peritoneal Cancer; Undifferentiated Ovarian Carcinoma
Gynecologic Oncology Group
2011-06
NCT00415324 COMPLETED
Unspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI)
2006-12 PHASE1
NCT01659554 TERMINATED
Recurrent Ovarian Cancer; Fallopian Tube Cancer
Columbia University
2012-03 PHASE2
NCT00334594 COMPLETED
Malignant Mesothelioma
Swiss Cancer Institute
2005-11-14 PHASE2
NCT00648648 COMPLETED
Solid Tumors
Merck Sharp & Dohme LLC
2008-02-25 PHASE1
NCT01663285 TERMINATED
Urothelial Cancer; Bladder Cancer
University of Michigan Rogel Cancer Center
2012-09 PHASE2
NCT01249352 COMPLETED
Esophageal Cancer; Adenocarcinoma
Eurofarma Laboratorios S.A.
2009-01 PHASE2; PHASE3
NCT00053352 COMPLETED
Childhood Embryonal Tumor; Childhood Extracranial Germ Cell Tumor; Childhood Extragonadal Germ Cell Tumor; Childhood Malignant Ovarian Germ Cell Tumor; Childhood Malignant Testicular Germ Cell Tumor; Childhood Teratoma; Ovarian Embryonal Carcinoma; Ovarian Yolk Sac Tumor; Stage II Malignant Testicular Germ Cell Tumor; Stage IIA Ovarian Germ Cell Tumor; Stage IIB Ovarian Germ Cell Tumor; Stage IIC Ovarian Germ Cell Tumor; Stage III Malignant Testicular Germ Cell Tumor; Stage IIIA Ovarian Germ Cell Tumor; Stage IIIB Ovarian Germ Cell Tumor; Stage IIIC Ovarian Germ Cell Tumor; Testicular Choriocarcinoma and Yolk Sac Tumor; Testicular Embryonal Carcinoma
Children's Oncology Group
2003-11-03 PHASE3
NCT01348009 UNKNOWN
Gastric Carcinoma
Genta Incorporated
2011-05 PHASE1; PHASE2
NCT00842712 COMPLETED
Carcinoma, Non-Small-Cell Lung
Merck KGaA, Darmstadt, Germany
2009-02 PHASE2
NCT00942825 COMPLETED
Metastatic Non-squamous Non Small Cell Lung Cancer
CanBas Co. Ltd.
2009-04 PHASE2
NCT01356368 TERMINATED
Non-Small Cell Lung Cancer
National Guard Health Affairs
2010-05 PHASE2
NCT00915382 COMPLETED
Advanced Gastric Cancer
Asan Medical Center
2009-01 PHASE3
NCT01633645 COMPLETED
Non Small Cell Lung Cancer; Metastatic
University Hospital of Crete
2009-06 PHASE2
NCT01096745 TERMINATED
Metastatic Biliary Tract Cancer; Locally Advanced Biliary Tract Cancer
Gyeongsang National University Hospital
2010-07 PHASE2
NCT01282333 TERMINATED
Advanced Adult Primary Liver Cancer; Localized Unresectable Adult Primary Liver Cancer; Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter; Regional Transitional Cell Cancer of the Renal Pelvis and Ureter; Stage III Bladder Cancer; Stage III Pancreatic Cancer; Stage IIIA Non-small Cell Lung Cancer; Stage IIIB Non-small Cell Lung Cancer; Stage IV Bladder Cancer; Stage IV Non-small Cell Lung Cancer; Stage IV Pancreatic Cancer; Transitional Cell Carcinoma of the Bladder; Unresectable Extrahepatic Bile Duct Cancer; Unresectable Gallbladder Cancer
National Cancer Institute (NCI)
2011-01 PHASE1
NCT00489944 UNKNOWN
Intraocular Melanoma
San Diego Pacific Oncology & Hematology Associates
2007-05 PHASE2
NCT00548418 COMPLETED
Cervical Cancer
Washington University School of Medicine
2007-02 PHASE2
NCT01073683 UNKNOWN
Larynx Cancer
Rabin Medical Center
2010-04 PHASE2
NCT01004250 COMPLETED
Non-Small Cell Lung Cancer
Eli Lilly and Company
2009-10 PHASE2
NCT00082862 UNKNOWN
Pancreatic Cancer
The University of Texas Health Science Center, Houston
2002-07 PHASE2
NCT01593306 UNKNOWN
Carcinoma Cervix
Indira Gandhi Medical College, Shimla
2011-07 PHASE3
NCT00771563 COMPLETED
Non-Small Cell Lung Cancer
University Hospital, Antwerp
2008-06 PHASE3
NCT00695032 SUSPENDED
Chemotherapeutic Agent Toxicity; Renal Toxicity; Unspecified Adult Solid Tumor, Protocol Specific
Institut Claudius Regaud
2007-10
NCT00632268 COMPLETED
Metastatic Gastric Cancer
National Taiwan University Hospital
2008-02 PHASE2
NCT00995761 COMPLETED
Non-small Cell Lung Cancer
Gyeongsang National University Hospital
2009-10 PHASE2
NCT01303978 COMPLETED
Chemotherapy-induced Nausea and Vomiting
Acacia Pharma Ltd
2011-02 PHASE2
NCT01016561 TERMINATED
Cervical Cancer
Abramson Cancer Center at Penn Medicine
2009-07
NCT01291095 UNKNOWN
HEAD AND NECK CANCER
All India Institute of Medical Sciences
2011-02 PHASE2
NCT01313663 TERMINATED
Lung Cancer, Small Cell
GlaxoSmithKline
2011-02 PHASE2
NCT00109928 COMPLETED
Lymphoma
SWOG Cancer Research Network
2005-09 PHASE2
NCT01083537 TERMINATED
Ovarian Cancer; Peritoneal Cancer; Fallopian Tube Cancer; Bowel Obstruction
University Health Network, Toronto
2010-02 PHASE1; PHASE2
NCT02133612 COMPLETED
Esophageal Cancer
Chinese Academy of Medical Sciences
2007-12 PHASE2
NCT01151761 TERMINATED
Cholangiocarcinoma; Hepatobiliary Neoplasm; Liver Cancer; Bile Duct Cancer; Cancer of Gallbladder
Stanford University
2011-01 PHASE2
NCT00193882 COMPLETED
Esophagus Cancer
Trans Tasman Radiation Oncology Group
2003-07-07 PHASE3
NCT00343239 COMPLETED
Stomach Neoplasms
Sanofi
2006-06 PHASE2
NCT00782574 COMPLETED
Advanced Solid Tumors
AstraZeneca
2008-11-12 PHASE1
NCT01069081 COMPLETED
Breast Cancer; Metastasis, Neoplasm
Fudan University
2009-08 PHASE2
NCT00823186 UNKNOWN
Cervical Cancer
Chang Gung Memorial Hospital
2009-02 PHASE1
NCT00545948 TERMINATED
Carcinoma, Non-Small-Cell Lung
Duke University
2007-12 PHASE2
NCT01336049 UNKNOWN
Esophageal Squamous Cell Cancer
Peking University
2011-03 PHASE2
NCT00714948 TERMINATED
Bladder Cancer; URINARY BLADDER
Memorial Sloan Kettering Cancer Center
2008-07 PHASE2
NCT01029873 COMPLETED
Metastatic Melanoma
Altor BioScience
2010-02 PHASE1; PHASE2
NCT00952497 COMPLETED
Gastric Cancer
ACT Biotech, Inc
2009-06 PHASE2
NCT01047007 TERMINATED
Solid Tumors
Merck Sharp & Dohme LLC
2010-01-18 PHASE1
NCT00062374 COMPLETED
Gastric Adenocarcinoma; Stage II Gastric Cancer; Stage III Gastric Cancer; Stage IV Gastric Cancer
National Cancer Institute (NCI)
2003-06 PHASE2
NCT00003907 COMPLETED
Liver Cancer; Metastatic Cancer
Eastern Cooperative Oncology Group
1999-12-15 PHASE2
NCT00747799 COMPLETED
Nasopharyngeal Neoplasms
Sun Yat-sen University
2009-01 PHASE2
NCT01360827 TERMINATED
Squamous Cell Carcinoma of the Head and Neck
Merck KGaA, Darmstadt, Germany
2010-08 PHASE1
NCT00169247 COMPLETED
Larynx Cancer; Hypopharynx Cancer
Groupe Oncologie Radiotherapie Tete et Cou
2005-10 PHASE2
NCT00436657 COMPLETED
Peritoneal Neoplasms; Retroperitoneal Neoplasms; Gastrointestinal Neoplasms; Adenocarcinoma; Neuroblastoma; Ovarian Neoplasms; Sarcoma; Adrenocortical Carcinoma; Wilms Tumor; Rhabdomyosarcoma; Desmoplastic Small Round Cell Tumor
M.D. Anderson Cancer Center
2007-02 PHASE1
NCT00005047 TERMINATED
Bladder Cancer
SWOG Cancer Research Network
1997-08 PHASE3
NCT00768755 COMPLETED
Carcinoma, Non-Small Cell Lung
Pfizer
2009-01 PHASE1; PHASE2
NCT00544362 COMPLETED
Esophageal Cancer
Federation Francophone de Cancerologie Digestive
2007-07 PHASE1; PHASE2
NCT00265941 COMPLETED
Head and Neck Cancer
Radiation Therapy Oncology Group
2005-11 PHASE3
NCT00634595 UNKNOWN
Head and Neck Squamous Carcinoma; Nasopharyngeal Carcinoma
Sun Yat-sen University
2008-03 PHASE2
NCT00616785 UNKNOWN
Lung Cancer
Yonsei University
2007-06 PHASE2
NCT00673179 TERMINATED
Osteosarcoma
M.D. Anderson Cancer Center
2008-05
NCT00719550 COMPLETED
Esophagogastric Junction Adenocarcinoma; Gastric Cancer; Esophageal Cancer
Amgen
2009-02 PHASE1; PHASE2
NCT00047112 COMPLETED
Esophageal Cancer
Federation Francophone de Cancerologie Digestive
2002-05 PHASE3
NCT02563054 COMPLETED
Gastric Cancer
Hoffmann-La Roche
2003-04 PHASE3
NCT00716417 COMPLETED
Neoplasms
Boehringer Ingelheim
2008-07-01 PHASE1
NCT00261703 COMPLETED
Head and Neck Neoplasms
Sanofi
2002-12 PHASE2; PHASE3
NCT00122772 COMPLETED
Cervix Cancer
International Atomic Energy Agency
2005-11 PHASE3
NCT00842491 COMPLETED
Advanced Gastric Cancer
Peking University
2008-11 PHASE2
NCT00449033 COMPLETED
Carcinoma, Non-Small-Cell Lung
Bayer
2007-02 PHASE3
NCT00278278 UNKNOWN
Brain and Central Nervous System Tumors
German Society for Pediatric Oncology and Hematology GPOH gGmbH
2003-09 PHASE3
NCT00118131 TERMINATED
Lung Cancer
University of Medicine and Dentistry of New Jersey
2003-12 PHASE2
NCT00826891 UNKNOWN
Cervical Cancer
Chinese Anti-Cancer Association
2009-02 PHASE2
NCT00209690 COMPLETED
Esophageal Cancer
Hokkaido Gastrointestinal Cancer Study Group
2003-10 PHASE1; PHASE2
NCT00450138 COMPLETED
Head and Neck Cancer
Sanofi
2006-12 PHASE1
NCT00548548 COMPLETED
Adenocarcinoma
Genentech, Inc.
2007-09 PHASE3
NCT01687439 COMPLETED
Non-small Cell Lung Cancer
Fudan University
2008-12 PHASE2
NCT00169221 TERMINATED
Head and Neck Cancer
Groupe Oncologie Radiotherapie Tete et Cou
2005-09 PHASE2
NCT00817258 UNKNOWN
Nasopharyngeal Carcinoma
Fudan University
2007-01 PHASE2
NCT00354393 COMPLETED
Malignant Mesothelioma
The Cleveland Clinic
2002-08 PHASE2
NCT00960284 COMPLETED
Pancreatic Cancer
IRCCS San Raffaele
2003-06 PHASE2; PHASE3
NCT00387127 COMPLETED
Neoplasms, Head and Neck
GlaxoSmithKline
2006-11 PHASE2
NCT00354549 COMPLETED
Lung Cancer
Swiss Cancer Institute
2006-01 PHASE2
NCT00700440 COMPLETED
Nasopharyngeal Carcinoma
Sun Yat-sen University
2008-07 PHASE2
NCT00886028 UNKNOWN
Malignant Pleural Mesothelioma
National Institute of Cancerología
2006-09 PHASE2
NCT00059761 COMPLETED
Lung Cancer
Radiation Therapy Oncology Group
2003-03 PHASE1
NCT03175939 COMPLETED
Nasopharyngeal Cancer
Sun Yat-sen University
1998-04-01 PHASE2
NCT00498953 COMPLETED
Head and Neck Cancer
European Organisation for Research and Treatment of Cancer - EORTC
2007-05 PHASE1; PHASE2
NCT00191139 COMPLETED
Non-small Cell Lung Cancer
Eli Lilly and Company
2003-03 PHASE2
NCT01839032 COMPLETED
Lung Cancer
Pierre Fabre Medicament
2005-05 PHASE2
NCT00191308 COMPLETED
Non-Small Cell Lung Cancer; Carcinoma
Eli Lilly and Company
2005-05 PHASE2
NCT00254904 TERMINATED
Carcinoma, Non-Small-Cell Lung
Pfizer
2005-11 PHASE3
NCT00443261 TERMINATED
Squamous Cell Carcinoma
University of Kansas Medical Center
2007-02 PHASE1
NCT00253370 COMPLETED
Adenocarcinoma of the Gastroesophageal Junction; Metastatic Gastric Cancer; Advanced Unresectable Gastric Cancer
National Cancer Institute (NCI)
2005-10 PHASE2
NCT00401609 COMPLETED
Small Cell Lung Cancer
National Cancer Institute, Naples
2000-11 PHASE1; PHASE2
NCT00106626 COMPLETED
Advanced Cancer
Merck Sharp & Dohme LLC
2005-08 PHASE1
NCT00003573 COMPLETED
Brain Tumors; Central Nervous System Tumors
Children's Oncology Group
1998-11 PHASE2
NCT00004188 COMPLETED
Neuroblastoma
Children's Oncology Group
2001-02 PHASE3
NCT00012012 COMPLETED
Cervical Cancer; Radiation Toxicity
Radiation Therapy Oncology Group
2001-08 PHASE1; PHASE2
NCT00077051 COMPLETED
Head and Neck Cancer
University of Miami
2004-04 PHASE1
NCT00059826 COMPLETED
Pancreatic Cancer
Alliance for Clinical Trials in Oncology
2003-03 PHASE2
NCT00101907 TERMINATED
Lung Cancer; Pancreatic Cancer; Esophageal Cancer
Amgen
2004-12 PHASE1
NCT00003945 COMPLETED
Cervical Cancer
Gynecologic Oncology Group
1999-06 PHASE3
NCT00139230 COMPLETED
Squamous Cell Carcinoma; Carcinoma of Head/Neck
Dana-Farber Cancer Institute
1997-01 PHASE2
NCT00401492 COMPLETED
Non Small Cell Lung Cancer
National Cancer Institute, Naples
2002-06 PHASE2
NCT00652860 COMPLETED
Metastatic Cancer; Sarcoma
Mayo Clinic
2001-08 PHASE2
NCT00055835 COMPLETED
Bladder Cancer; Urethral Cancer
SWOG Cancer Research Network
2002-11 PHASE2
NCT00002984 COMPLETED
Esophageal Cancer
UNC Lineberger Comprehensive Cancer Center
1997-03 PHASE1; PHASE2
NCT00021333 COMPLETED
Head and Neck Cancer; Lung Cancer
Fox Chase Cancer Center
1999-09 PHASE2
NCT00020696 COMPLETED
Ovarian Cancer; Primary Peritoneal Cavity Cancer
Gynecologic Oncology Group
2001-06 PHASE2
NCT00139243 COMPLETED
Squamous Cell Carcinoma; Carcinoma of Head and/or Neck
Dana-Farber Cancer Institute
1997-10 PHASE1; PHASE2
NCT00916097 COMPLETED
Head and Neck Neoplasms
Sanofi
2002-07 PHASE2
NCT00005814 COMPLETED
Head and Neck Cancer
Memorial Sloan Kettering Cancer Center
1999-12 PHASE2
NCT00154739 COMPLETED
Non-Small Cell Lung Cancer
National Taiwan University Hospital
1998-10 PHASE2
NCT00006248 COMPLETED
Head and Neck Cancer
SWOG Cancer Research Network
2000-11 PHASE2
NCT00165464 COMPLETED
Esophageal Cancer; Gastric Cancer; GE Junction Cancer
Dana-Farber Cancer Institute
2001-08 PHASE2
NCT00003809 COMPLETED
Head and Neck Cancer
Eastern Cooperative Oncology Group
1999-08-06 PHASE3
NCT00003691 COMPLETED
Endometrial Cancer
Gynecologic Oncology Group
1998-12 PHASE3
NCT00006942 COMPLETED
Fallopian Tube Cancer; Primary Peritoneal Cavity Cancer; Recurrent Ovarian Epithelial Cancer; Stage III Ovarian Epithelial Cancer; Stage IV Ovarian Epithelial Cancer
National Cancer Institute (NCI)
2000-10 PHASE2
NCT00003624 TERMINATED
Cervical Cancer; Endometrial Cancer; Fallopian Tube Cancer; Neurotoxicity; Ovarian Cancer; Primary Peritoneal Cavity Cancer; Sarcoma
Gynecologic Oncology Group
1998-12 PHASE2
NCT00043927 COMPLETED
Small Cell Lung Cancer
GlaxoSmithKline
2001-04 PHASE3
NCT00030862 COMPLETED
Esophageal Cancer
Memorial Sloan Kettering Cancer Center
2001-10 PHASE2
NCT01693718 COMPLETED
Head and Neck
University of Chicago
2003-03 PHASE2
NCT00057850 COMPLETED
Head and Neck Cancer
National Cancer Institute (NCI)
2002-01 PHASE1; PHASE2
NCT00004189 COMPLETED
Lymphoma; Small Intestine Cancer; Unspecified Adult Solid Tumor, Protocol Specific
National Cancer Institute (NCI)
1999-10 PHASE1
NCT00004920 COMPLETED
Malignant Mesothelioma
European Organisation for Research and Treatment of Cancer - EORTC
1999-11 PHASE3
NCT00002559 COMPLETED
Ovarian Cancer; Testicular Germ Cell Tumor
Memorial Sloan Kettering Cancer Center
1994-01 PHASE1; PHASE2
NCT00003996 COMPLETED
Brain and Central Nervous System Tumors
Alliance for Clinical Trials in Oncology
1999-05 PHASE2
NCT00003642 TERMINATED
Bladder Cancer
European Organisation for Research and Treatment of Cancer - EORTC
1998-10 PHASE2
NCT00003032 COMPLETED
Breast Cancer
NCIC Clinical Trials Group
1997-04-25 PHASE3
NCT00003587 COMPLETED
Lung Cancer
SWOG Cancer Research Network
1998-10 PHASE2
NCT00002783 COMPLETED
Gastric Cancer
Memorial Sloan Kettering Cancer Center
1996-05 PHASE2
NCT00003358 COMPLETED
Fallopian Tube Cancer; Ovarian Cancer; Primary Peritoneal Cavity Cancer
Memorial Sloan Kettering Cancer Center
1998-01 PHASE1
NCT00003231 COMPLETED
Lung Cancer
Swiss Cancer Institute
1997-04 PHASE2
NCT00003589 COMPLETED
Lung Cancer
European Organisation for Research and Treatment of Cancer - EORTC
1998-08 PHASE3
NCT00002993 TERMINATED
Sarcoma
Gynecologic Oncology Group
1997-08 PHASE2
NCT00002631 COMPLETED
Esophageal Cancer
Radiation Therapy Oncology Group
1995-06 PHASE3
NCT00003912 COMPLETED
Liver Cancer
Societe Internationale d'Oncologie Pediatrique
1998-06 PHASE3
NCT00510107 UNKNOWN
Stomach Neoplasm; Stage IV; Recurrent
Gachon University Gil Medical Center
2007-07 PHASE2
NCT00290966 COMPLETED
Stomach Neoplasm
Sanofi
1998-10 PHASE2; PHASE3
NCT00004900 COMPLETED
Breast Cancer
Hackensack Meridian Health
1999-10 PHASE2
NCT00003643 UNKNOWN
Extragonadal Germ Cell Tumor; Teratoma; Testicular Germ Cell Tumor
European Organisation for Research and Treatment of Cancer - EORTC
1998-10 PHASE2; PHASE3
NCT00201383 COMPLETED
Oral Cavity; Squamous Cell Carcinoma
National Health Research Institutes, Taiwan
1999-10 PHASE3
NCT00269997 COMPLETED
Anemia; Neoplasms
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
PHASE2
NCT00017459 COMPLETED
Lung Cancer
Sanofi
2000-07 PHASE3
NCT00003580 COMPLETED
Drug/Agent Toxicity by Tissue/Organ; Head and Neck Cancer; Oral Complications; Radiation Toxicity
University of Tennessee
1998-06 PHASE2
NCT00004100 UNKNOWN
Lung Cancer
Istituto Nazionale per lo Studio e la Cura dei Tumori
1998-11 PHASE3
NCT00365755 COMPLETED
Neuroblastoma
Children's Cancer and Leukaemia Group
PHASE3
NCT00191763 COMPLETED
Carcinoma, Non-Small-Cell-Lung Cancer
Eli Lilly and Company
2002-11 PHASE2
NCT00003182 UNKNOWN
Head and Neck Cancer
Hope Cancer Institute, Inc.
1997-03 PHASE1; PHASE2
NCT00490880 COMPLETED
Bladder Cancer
Eli Lilly and Company
2003-11 PHASE2
NCT00477867 WITHDRAWN
Ovarian Cancer
Gynecologic Oncology Group
NCT00220129 COMPLETED
Oesophageal Carcinoma
Royal Marsden NHS Foundation Trust
2002-11 PHASE2

(data from https://clinicaltrials.gov, updated on 2026-07-29)

Check the Cisplatin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Cisplatin directly binds to genomic DNA to form platinum-DNA adducts, which severely obstructs DNA replication machinery and halts transcription cascades. This persistent genomic damage activates downstream apoptotic signaling pathways and ferroptosis, driving tumor cell death and inhibiting disease progression in clinical conditions such as non-small cell lung cancer, urothelial carcinoma, and head and neck cancer.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

Note: Technical data last updated: Sep 1, 2026.