CAS No. 610309-89-2

Batch: Purity:98
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Carvedilol Phosphate Chemical Structure
Chemical Structure
Check the Carvedilol Phosphate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name bis(1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol);phosphoric acid;hydrate
CAS Number 610309-89-2
Molecular Formula

C24H29N2O8P.1/2H2O
Molecular Weight (MW) 513.48
SMILES COC1=CC=CC=C1OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O.COC1=CC=CC=C1OCCNCC(COC2=CC=CC3=C2C4=CC=CC=C4N3)O.O.OP(=O)(O)O.OP(=O)(O)O
InChIKey LHNYXTULDSJZRB-UHFFFAOYSA-N

Ordering Information

Biological Activity

Carvedilol Phosphate is a non-selective β-adrenergic receptor antagonist and α1-adrenergic receptor blocker. By targeting β1-, β2-, and α1-adrenoceptors, it inhibits sympathetic nervous system signaling, reduces peripheral vascular resistance, and attenuates adrenergic-mediated vasoconstriction. Additionally, carvedilol exerts potent cellular antioxidant effects and suppresses vascular smooth muscle cell proliferation to effectively regulate cardiovascular hemodynamics and vascular tone.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (194.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.