Synonyms: Ccl2,MCP-1
Carlumab (Anti-CCL2 / MCP1) is a humanised monoclonal antibody targeting CCL2 with high affinity. Carlumab can be used in cancer research, particularly in prostate cancer. MW:145.5 KD.
| Featured Inhibitors | Y-27632 Dihydrochloride SB431542 CHIR-99021 (Laduviglusib) RMC-7977 RMC-6236 (Daraxonrasib) MRTX1133 MG132 Z-VAD-FMK VT3989 IAG933 |
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| Description |
Carlumab (Anti-CCL2 / MCP1) is a humanised monoclonal antibody targeting CCL2 with high affinity. Carlumab can be used in cancer research, particularly in prostate cancer. MW:145.5 KD.
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| CAS No. | 915404-94-3 |
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| Molecular Weight | 145.5 kDa |
| Isotype | Human IgG1 |
| Source | CHO |
| Purification | AKTA |
| Sterility | 0.2 μM filtered |
| Formulation | 100 mM Pro-Ac, 20mM Arg, pH5.0 |
| Storage (From the date of receipt) |
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)
| NCT Number | Recruitment | interventions | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|---|
| NCT07651397 | NOT_YET_RECRUITING | Autosomal Dominant Polycystic Kidney Disease (ADPKD) | Assaf-Harofeh Medical Center | 2026-07-10 | ||
| NCT02261545 | UNKNOWN | Diabetes Mellitus Type II | Tehran University of Medical Sciences | 2014-09 | PHASE4 | |
| NCT01340222 | COMPLETED | Preterm Labour | Centre Hospitalier Universitaire Dijon | 2011-03 | ||
| NCT00992186 | COMPLETED | Drug: Carlumab | Prostate Cancer | Centocor Research & Development, Inc. | 2009-09 | PHASE2 |
| NCT00385931 | COMPLETED | Drug: Valsartan and simvastatin | Hypertension; Hypercholesterolemia; Dyslipidemia | Novartis | 2002-01 | PHASE3 |
| NCT01204996 | COMPLETED | Drug: CNTO888+DOXIL®/ Caelyx® doxorubicin HCl liposome injec | Cancer | Centocor, Inc. | 2010-05 | PHASE1 |
(data from https://clinicaltrials.gov, updated on 2026-06-26)
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