Home Biosimilar Antibodies Immunology & Inflammation Interleukins Camidanlumab (Anti-IL-2Ra / CD25)
For research use only. Not for use in humans.

Camidanlumab (Anti-IL-2Ra / CD25)

Synonyms: IL-2-RA， CD25

Camidanlumab (HuMax-TAC) is a human IgG1 monoclonal antibody directed against CD25 (IL-2R alpha), which is overexpressed in a variety of hematological tumors. MW: 143.98 KD.

Camidanlumab (Anti-IL-2Ra / CD25)

Quality Control

Batch: A296801 Purity: 99% Protein concentration: 6.043mg/ml Endotoxin Level: ＜1EU/mg
99

Specificity

Name Citation IL-6 IL-1 IL-8 IL-12 IL-10 IL-13 IL-2 Others
SKF-86002 1
JTE-607 Dihydrochloride 2 TNF-alpha
A-740003 2 rat P2X7 receptor,human P2X7 receptor
Apilimod mesylate 6 PIKfyve
MD2-TLR4-IN-1 2 TLR4,TNF-α
Danirixin (GSK1325756) 2 CXCR2
Resatorvid (TAK-242) 65 TLR4,NO,TNF-α
Apilimod (STA-5326) 19 PIKfyve
LMT-28 1
Atractylodin 0 NAAA
Triolein 0 ROS,MMP-1
Ac-YVAD-cmk 5
Diethyl phosphate 1
RCM-1 5 STAT6,FOXM1,β-catenin
Stylopine 0 COX-2,TNF-α,NO
Myrislignan 1 NF-κB,COX-2,iNOS
NE 52-QQ57 2 iNOS,TNF-α,PGE2
PKR-IN-C16 9 PKR
(3R,8S)-Falcarindiol 3 STAT,ERK,JNK
Gardenoside 1 P2X7 Receptor,P2X3 receptor,NF-κB
T-5224 23 c-Jun,c-Fos/AP-1,Adamts-5
IQ 3 1 TNF-α,JNK3,JNK1
Isuzinaxib (APX-115 free base) 2 TNFα,MCP-1/CCL2,NOX2
AUDA 1 p38,Smad3,TGF-β
SAR-20347 1 IFN-α,TYK2,JAK1
SU 5201 0
Madecassic acid 3 TNF-α,COX-2,iNOS
Homoplantaginin 1 NF-κB,IKKβ,TNF-α
2',5'-Dihydroxyacetophenone 1 NF-κB,ERK1/2,iNOS
Forsythoside B 0 NF-κB,TNF-alpha,IκB
Mulberroside A 0 NF-κB,Caspase-1,NALP3
Chelidonic acid 0 glutamate decarboxylase,Caspase-1,NF-κB
4-Methylesculetin 2 MPO
Muscone 4 TNF-α,NLRP3 inflammasome,NF-κB
Ossirene (AS101) 16
Methylthiouracil 1 ERK1/2,NF-κB,TNF-α
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Camidanlumab (HuMax-TAC) is a human IgG1 monoclonal antibody directed against CD25 (IL-2R alpha), which is overexpressed in a variety of hematological tumors. MW: 143.98 KD.
References

Product Details

CAS No. 921618-45-3
Molecular Weight 143.98
Isotype Human IgG1
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT06688331 RECRUITING Presymptomatic Diabetes Type 1 (Stage 1); Diabetes Mellitus, Type I; Diabetes Mellitus, Type 1 PolTREG S.A. 2025-03-12 PHASE2
NCT07029958 RECRUITING Drug: recombinant humanized anti-CD25 monoclonal antibody EBV-T/NK LPD Beijing Children's Hospital 2024-11-12 PHASE4
NCT04871607 RECRUITING Drug: Carmustine|Drug: Cytarabine|Drug: Etoposide Recurrent Hodgkin Lymphoma; Refractory Hodgkin Lymphoma City of Hope Medical Center 2021-11-02 PHASE2
NCT07689630 RECRUITING Drug: Methotrexate Graft Versus Host Disease; Hematologic Neoplasms Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 2026-05-01 PHASE3
NCT06364319 NOT_YET_RECRUITING Drug: anti-CD25 rhMAb|Drug: Prednisone|Drug: Ruxolitinib|Dru cGVHD Peking University People's Hospital 2026-07-15 PHASE4
NCT06657391 RECRUITING Drug: recombinant humanized anti-CD25 monoclonal antibody Transfusion Dependent Thalassemia Rongrong Liu 2024-10-01 PHASE2

(data from https://clinicaltrials.gov, updated on 2026-07-17)

Tech Support

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