Clinical Trials
Numerous clinical trials spanning Early Phase 1 through Phase 4 evaluate calcium folinate across oncology—including metastatic colorectal cancer, esophageal squamous cell carcinoma, osteosarcoma, and advanced solid tumors—as well as neurodevelopmental conditions like autism spectrum and language disorders. Encompassing recruiting, active not recruiting, completed, and terminated protocols, these studies are sponsored by pharmaceutical leaders such as Bristol-Myers Squibb, academic medical centers, non-profits, and government entities including the United States Department of Defense.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT03959085 | RECRUITING | B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma; Central Nervous System Leukemia; Mixed Phenotype Acute Leukemia; Testicular Leukemia |
Children's Oncology Group |
2019-10-31 | PHASE3 |
| NCT03801876 | ACTIVE_NOT_RECRUITING | Clinical Stage I Esophageal Adenocarcinoma AJCC v8; Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8; Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage II Esophageal Adenocarcinoma AJCC v8; Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8; Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage III Esophageal Adenocarcinoma AJCC v8; Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8; Clinical Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8; Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8; Thoracic Esophagus Squamous Cell Carcinoma |
NRG Oncology |
2019-06-26 | PHASE3 |
| NCT07636564 | NOT_YET_RECRUITING | Acute Leukemia of Ambiguous Lineage; B Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative; T Acute Lymphoblastic Leukemia |
SWOG Cancer Research Network |
2026-10-14 | PHASE2 |
| NCT07271355 | NOT_YET_RECRUITING | Metastatic Appendix Carcinoma; Metastatic Colorectal Carcinoma; Metastatic Malignant Neoplasm in the Peritoneum; Stage IV Appendix Carcinoma AJCC v8; Stage IVC Colorectal Cancer AJCC v8; Unresectable Colorectal Carcinoma |
City of Hope Medical Center |
2026-10-01 | PHASE3 |
| NCT00004317 | RECRUITING | Toxoplasmosis |
National Institute of Allergy and Infectious Diseases (NIAID) |
2000-07 | PHASE4 |
| NCT06958328 | RECRUITING | Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma; Stage II Pancreatic Cancer AJCC v8; Stage III Pancreatic Cancer AJCC v8; Stage IV Pancreatic Cancer AJCC v8 |
NRG Oncology |
2025-08-21 | PHASE3 |
| NCT07412613 | RECRUITING | Resectable Colon Cancer; MSI-H/dMMR Colorectal Cancer |
Akeso |
2026-04-15 | PHASE3 |
| NCT06478238 | RECRUITING | Hereditary Spastic Paraplegia |
Shanghai 6th People's Hospital |
2024-07-01 | EARLY_PHASE1 |
| NCT07328919 | NOT_YET_RECRUITING | Intrahepatic Cholangiocarcinoma (Icc); Advanced Cholangiocarcinoma |
TransThera Sciences (Nanjing), Inc. |
2026-01 | PHASE3 |
| NCT06469944 | RECRUITING | Gastroesophageal Junction; Gastroesophageal Adenocarcinoma; Esophageal Neoplasms; Esophageal Cancer |
Merck Sharp & Dohme LLC |
2024-09-20 | PHASE1; PHASE2 |
| NCT07621497 | NOT_YET_RECRUITING | Metastatic Colorectal Cancer (CRC) |
Sun Yat-sen University |
2026-06-01 | PHASE2 |
| NCT07318805 | RECRUITING | Advanced Breast Cancer; Metastatic Breast Cancer (HR+/ HER2-); Colorectal Cancer; Metastatic Colorectal Adenocarcinoma; Triple Negative Breast Cancer |
Pfizer |
2025-12-23 | PHASE1 |
| NCT07775287 | RECRUITING | Colorectal Cancer |
Genmab |
2026-09-15 | PHASE3 |
| NCT07099794 | NOT_YET_RECRUITING | Biliary Tract Cancer (BTC) |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
2025-08-01 | PHASE2 |
| NCT04340141 | ACTIVE_NOT_RECRUITING | Pancreatic Adenosquamous Carcinoma; Resectable Pancreatic Adenocarcinoma; Stage I Pancreatic Cancer AJCC v8; Stage II Pancreatic Cancer AJCC v8; Stage III Pancreatic Cancer AJCC v8 |
Alliance for Clinical Trials in Oncology |
2020-10-13 | PHASE3 |
| NCT06317662 | RECRUITING | Acute Leukemia of Ambiguous Lineage; B Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2025-06-05 | PHASE2 |
| NCT07621718 | RECRUITING | Pancreatic Cancer; Pancreatic Cancer Metastatic; PDAC; PDAC - Pancreatic Ductal Adenocarcinoma; Pancreatic Ductal Adenocarcinoma (PDAC); Pancreatic Adenocarcinoma Metastatic; Pancreatic Adenocarcinoma; Pancreatic Adenosquamous Carcinoma |
Revolution Medicines, Inc. |
2026-05-22 | PHASE3 |
| NCT06662786 | RECRUITING | Colorectal Neoplasms |
Janssen Research & Development, LLC |
2024-10-18 | PHASE3 |
| NCT07737600 | NOT_YET_RECRUITING | Advanced Colorectal Cancer |
Lepu Biopharma Co., Ltd. |
2026-08 | PHASE1; PHASE2 |
| NCT05677490 | RECRUITING | Advanced Esophageal Adenocarcinoma; Advanced Gastric Adenocarcinoma; Advanced Gastroesophageal Junction Adenocarcinoma; Clinical Stage III Esophageal Adenocarcinoma AJCC v8; Clinical Stage III Gastric Cancer AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IV Esophageal Adenocarcinoma AJCC v8; Clinical Stage IV Gastric Cancer AJCC v8; Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8; Metastatic Esophageal Adenocarcinoma; Metastatic Gastric Adenocarcinoma; Metastatic Gastroesophageal Junction Adenocarcinoma; Unresectable Esophageal Adenocarcinoma; Unresectable Gastric Adenocarcinoma; Unresectable Gastroesophageal Junction Adenocarcinoma |
Alliance for Clinical Trials in Oncology |
2023-01-31 | PHASE3 |
| NCT07238283 | RECRUITING | First-line Treatment of Metastatic Pancreatic Cancer |
Jiangsu HengRui Medicine Co., Ltd. |
2025-12-02 | PHASE3 |
| NCT05292664 | RECRUITING | Myelodysplastic Syndromes, de Novo; Myelodysplastic Syndromes, Secondary; Myelodysplastic Syndromes, Previously Treated; Treatment-Related Acute Myeloid Leukemia; Therapy-Related Myelodysplastic Syndrome; Acute Lymphoblastic Leukemia, in Relapse; Acute Lymphoblastic Leukemia With Failed Remission; Lymphoblastic Lymphoma, in Relapse; Lymphoblastic Lymphoma, Refractory; Acute Leukemia of Ambiguous Lineage in Relapse; Acute Leukemia of Ambiguous Lineage |
Andrew E. Place, MD |
2023-03-29 | PHASE1 |
| NCT07595913 | NOT_YET_RECRUITING | Neuroendocrine Carcinoma |
Suzhou Zelgen Biopharmaceuticals Co.,Ltd |
2026-07 | PHASE3 |
| NCT06247787 | RECRUITING | Recurrent Childhood Acute Myeloid Leukemia; Recurrent Childhood Myelodysplastic Syndrome; Recurrent Juvenile Myelomonocytic Leukemia; Refractory Childhood Acute Myeloid Leukemia; Refractory Childhood Myelodysplastic Syndrome; Refractory Juvenile Myelomonocytic Leukemia |
Children's Oncology Group |
2025-02-04 | PHASE1 |
| NCT04248452 | ACTIVE_NOT_RECRUITING | Clinical Stage IV Esophageal Adenocarcinoma AJCC v8; Clinical Stage IV Gastric Cancer AJCC v8; Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8; Clinical Stage IVA Gastric Cancer AJCC v8; Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8; Clinical Stage IVB Gastric Cancer AJCC v8; Metastatic Esophageal Adenocarcinoma; Metastatic Gastric Adenocarcinoma; Oligometastatic Esophageal Adenocarcinoma; Oligometastatic Gastric Adenocarcinoma; Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8; Pathologic Stage IV Gastric Cancer AJCC v8; Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8; Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8 |
ECOG-ACRIN Cancer Research Group |
2020-05-26 | PHASE3 |
| NCT07015242 | RECRUITING | Lymphoma |
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company |
2025-11-06 | PHASE2 |
| NCT07705919 | NOT_YET_RECRUITING | Borderline Resectable Pancreatic Ductal Adenocarcinoma |
Ohio State University Comprehensive Cancer Center |
2026-09-01 | PHASE1; PHASE2 |
| NCT06750094 | RECRUITING | Colorectal Neoplasms |
Janssen Research & Development, LLC |
2024-12-12 | PHASE3 |
| NCT05026905 | ACTIVE_NOT_RECRUITING | Phase II, Open-label, Parallel 2-arm, Multi-center |
National Health Research Institutes, Taiwan |
2021-12-28 | PHASE2 |
| NCT07337460 | RECRUITING | Hepatocellular Carcinoma (HCC) |
Northern Jiangsu People's Hospital |
2025-11-01 | PHASE2 |
| NCT06780787 | RECRUITING | Rectal Adenocarcinoma; Stage IIA Rectal Cancer AJCC v8; Stage III Rectal Cancer AJCC v8 |
City of Hope Medical Center |
2025-05-20 | PHASE2 |
| NCT07069712 | RECRUITING | Gastroesophageal Adenocarcinoma |
AstraZeneca |
2025-07-17 | PHASE2 |
| NCT06544655 | ACTIVE_NOT_RECRUITING | Advanced Solid Tumors |
Bristol-Myers Squibb |
2024-10-10 | PHASE1 |
| NCT03914625 | ACTIVE_NOT_RECRUITING | B Acute Lymphoblastic Leukemia; B Lymphoblastic Lymphoma; Down Syndrome |
National Cancer Institute (NCI) |
2019-07-03 | PHASE3 |
| NCT07337421 | RECRUITING | Hepatocellular Carcinoma (HCC) |
Northern Jiangsu People's Hospital |
2025-09-01 | PHASE2 |
| NCT07363408 | NOT_YET_RECRUITING | Advanced Microsatellite Stable Colorectal Carcinoma; Metastatic Microsatellite Stable Colorectal Carcinoma; Stage III Colorectal Cancer AJCC v8; Stage IV Colorectal Cancer AJCC v8 |
City of Hope Medical Center |
2026-12-01 | PHASE1 |
| NCT02997228 | ACTIVE_NOT_RECRUITING | Metastatic Colorectal Adenocarcinoma; Stage IV Colorectal Cancer AJCC v7 |
National Cancer Institute (NCI) |
2018-01-19 | PHASE3 |
| NCT06078709 | RECRUITING | Clinical Stage I Esophageal Adenocarcinoma AJCC v8; Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage II Esophageal Adenocarcinoma AJCC v8; Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage III Esophageal Adenocarcinoma AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 |
Mayo Clinic |
2023-11-20 | PHASE2 |
| NCT00492999 | ACTIVE_NOT_RECRUITING | Colorectal Cancer; Metastatic Cancer |
Memorial Sloan Kettering Cancer Center |
2007-05 | PHASE2 |
| NCT07441369 | ENROLLING_BY_INVITATION | Liver Metastases From Colorectal Cancer (mCRC) |
Fudan University |
2026-07-30 | PHASE2 |
| NCT07056777 | RECRUITING | Gastrointestinal Cancer |
Zhejiang Doer Biologics Co., Ltd. |
2025-03-25 | PHASE1; PHASE2 |
| NCT05802056 | ACTIVE_NOT_RECRUITING | Clinical Stage IV Gastric Cancer AJCC v8; Gastric Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma; Metastatic Gastric Carcinoma; Metastatic Malignant Neoplasm in the Peritoneum |
Mayo Clinic |
2023-11-29 | PHASE1 |
| NCT06648525 | NOT_YET_RECRUITING | Intrahepatic Cholangiocarcinoma (Icc) |
Harbin Medical University |
2024-10 | PHASE2 |
| NCT06217042 | NOT_YET_RECRUITING | Pancreatic Cancer |
Fudan University |
2024-02-05 | PHASE3 |
| NCT06821997 | RECRUITING | Borderline Resectable Pancreatic Ductal Adenocarcinoma |
Roswell Park Cancer Institute |
2026-03-02 | PHASE2 |
| NCT06383078 | NOT_YET_RECRUITING | Efficacy and Safety |
The First Affiliated Hospital with Nanjing Medical University |
2024-04-20 | PHASE2 |
| NCT04205968 | RECRUITING | Metastatic Small Intestinal Adenocarcinoma; Stage III Small Intestinal Adenocarcinoma AJCC v8; Stage IIIA Small Intestinal Adenocarcinoma AJCC v8; Stage IIIB Small Intestinal Adenocarcinoma AJCC v8; Stage IV Small Intestinal Adenocarcinoma AJCC v8 |
SWOG Cancer Research Network |
2020-06-01 | PHASE2 |
| NCT07446465 | NOT_YET_RECRUITING | Colorectal Cancer (Locally Advanced or Metastatic); Colorectal Cancer Microsatellite Stable (MSS) |
Ye Xu |
2026-03-01 | PHASE4 |
| NCT04927780 | ACTIVE_NOT_RECRUITING | Pancreatic Cancer; Pancreatic Ductal Adenocarcinoma; Resectable Pancreatic Adenocarcinoma |
Erasmus Medical Center |
2021-09-07 | PHASE3 |
| NCT06696768 | RECRUITING | Metastatic Colorectal Adenocarcinoma; Stage III Colorectal Cancer AJCC v8; Stage IV Colorectal Cancer AJCC v8; Unresectable Colorectal Adenocarcinoma |
National Cancer Institute (NCI) |
2025-06-23 | PHASE1 |
| NCT04460352 | RECRUITING | Esophageal Squamous Cell Carcinoma |
Karolinska University Hospital |
2020-11-27 | PHASE3 |
| NCT06531278 | RECRUITING | Pancreatic Cancer Metastatic to Liver |
Jiang Long |
2024-07-16 | PHASE2 |
| NCT02981628 | ACTIVE_NOT_RECRUITING | Recurrent B Acute Lymphoblastic Leukemia; Recurrent B Lymphoblastic Lymphoma; Refractory B Acute Lymphoblastic Leukemia; Refractory B Lymphoblastic Lymphoma |
Children's Oncology Group |
2017-06-19 | PHASE2 |
| NCT05688215 | RECRUITING | Borderline Resectable Pancreatic Adenocarcinoma; Locally Advanced Pancreatic Ductal Adenocarcinoma |
Jonsson Comprehensive Cancer Center |
2023-03-07 | PHASE1; PHASE2 |
| NCT03020030 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia, Pediatric |
Dana-Farber Cancer Institute |
2017-03-03 | PHASE3 |
| NCT06447662 | ACTIVE_NOT_RECRUITING | Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung |
Pfizer |
2024-06-27 | PHASE1 |
| NCT05564403 | ACTIVE_NOT_RECRUITING | Advanced Biliary Tract Carcinoma; Advanced Gallbladder Carcinoma; Advanced Intrahepatic Cholangiocarcinoma; Recurrent Biliary Tract Carcinoma; Recurrent Gallbladder Carcinoma; Recurrent Intrahepatic Cholangiocarcinoma; Stage III Distal Bile Duct Cancer AJCC v8; Stage III Gallbladder Cancer AJCC v8; Stage III Hilar Cholangiocarcinoma AJCC v8; Stage III Intrahepatic Cholangiocarcinoma AJCC v8; Stage IV Distal Bile Duct Cancer AJCC v8; Stage IV Gallbladder Cancer AJCC v8; Stage IV Hilar Cholangiocarcinoma AJCC v8; Stage IV Intrahepatic Cholangiocarcinoma AJCC v8; Unresectable Biliary Tract Carcinoma; Unresectable Gallbladder Carcinoma; Unresectable Intrahepatic Cholangiocarcinoma |
National Cancer Institute (NCI) |
2024-02-09 | PHASE2 |
| NCT05945823 | ACTIVE_NOT_RECRUITING | Locally Advanced Unresectable or Metastatic Solid Tumors Including Esophageal Cancer; Esophageal Adenocarcinoma; Esophageal Squamous Cell Cancer; Siewert Type 1 GEJ Cancer; Pancreatic Cancer |
Taiho Oncology, Inc. |
2023-07-13 | PHASE2 |
| NCT05610163 | ACTIVE_NOT_RECRUITING | Stage II Rectal Cancer AJCC v8; Stage III Rectal Cancer AJCC v8; Locally Advanced Rectal Adenocarcinoma |
Alliance for Clinical Trials in Oncology |
2022-12-08 | PHASE2; PHASE3 |
| NCT04060017 | ACTIVE_NOT_RECRUITING | Autism Spectrum Disorder; Language Disorders |
Southwest Autism Research & Resource Center |
2020-09-22 | PHASE2 |
| NCT06313801 | RECRUITING | Gastric Cancer |
Nizhny Novgorod Regional Clinical Oncology Center |
2023-01-19 | PHASE2 |
| NCT06741020 | RECRUITING | Hepatocellular Carcinoma (HCC) |
Zhejiang Cancer Hospital |
2025-03-01 | PHASE1; PHASE2 |
| NCT04375605 | COMPLETED | Gastroesophageal Junction Adenocarcinoma |
Universitätsmedizin Mannheim |
2020-06-03 | PHASE3 |
| NCT03007147 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia; Mixed Phenotype Acute Leukemia; T Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2017-08-08 | PHASE3 |
| NCT02366819 | SUSPENDED | Esophageal Adenocarcinoma; Gastric Adenocarcinoma; Stage IIB Gastric Cancer; Stage IIIA Esophageal Adenocarcinoma; Stage IIIA Gastric Cancer; Stage IIIB Esophageal Adenocarcinoma; Stage IIIB Gastric Cancer; Stage IIIC Esophageal Adenocarcinoma; Stage IIIC Gastric Cancer |
University of Chicago |
2014-12-11 | PHASE4 |
| NCT07542002 | RECRUITING | Pancreatic Cancer |
Ningbo Medical Center Lihuili Hospital |
2025-03-25 | PHASE2 |
| NCT07543744 | RECRUITING | Metastatic Colorectal Cancer |
R-Pharm |
2025-04-17 | PHASE1 |
| NCT06704724 | TERMINATED | Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung |
Pfizer |
2024-12-10 | PHASE1 |
| NCT05846867 | ACTIVE_NOT_RECRUITING | Colorectal Cancer |
Akeso |
2023-05-08 | PHASE1; PHASE2 |
| NCT06993025 | NOT_YET_RECRUITING | Biliary Tract Cancer |
Tianjin Medical University Cancer Institute and Hospital |
2025-05-25 | PHASE2 |
| NCT02723994 | COMPLETED | Leukemia |
Incyte Corporation |
2016-09-30 | PHASE2 |
| NCT04233866 | ACTIVE_NOT_RECRUITING | Metastatic Pancreatic Adenocarcinoma; Stage IV Pancreatic Cancer AJCC v8 |
ECOG-ACRIN Cancer Research Group |
2020-08-26 | PHASE2 |
| NCT07334587 | ENROLLING_BY_INVITATION | Metastatic Colorectal Carcinoma (mCRC) |
Allama Iqbal Medical College |
2025-09-01 | |
| NCT06184698 | RECRUITING | Colorectal Cancer |
Hebei Medical University Fourth Hospital |
2024-01-01 | PHASE2 |
| NCT04210115 | COMPLETED | Esophageal Squamous Cell Carcinoma (ESCC); Gastroesophageal Junction Carcinoma (GEJC); Esophageal Adenocarcinoma (EAC) |
Merck Sharp & Dohme LLC |
2020-02-28 | PHASE3 |
| NCT05836584 | ACTIVE_NOT_RECRUITING | Clinical Stage I Gastric Cancer AJCC v8; Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage II Gastric Cancer AJCC v8; Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage III Gastric Cancer AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IVA Gastric Cancer AJCC v8; Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8; Gastric Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma |
National Cancer Institute (NCI) |
2023-12-06 | PHASE2 |
| NCT06703177 | RECRUITING | Advanced Solid Tumors |
Suzhou Suncadia Biopharmaceuticals Co., Ltd. |
2025-02-18 | PHASE1; PHASE2 |
| NCT05945901 | ACTIVE_NOT_RECRUITING | Colorectal Cancer |
Jiangsu HengRui Medicine Co., Ltd. |
2023-08-14 | PHASE2; PHASE3 |
| NCT03366155 | COMPLETED | Colorectal Cancer; Liver Metastases; Colorectal Adenocarcinoma; Colorectal Cancer With Hepatic Metastases; Colorectal Carcinoma |
National Cancer Institute (NCI) |
2019-06-24 | PHASE2 |
| NCT04821284 | ACTIVE_NOT_RECRUITING | Locally Advanced Pancreatic Ductal Adenocarcinoma; Metastatic Pancreatic Ductal Adenocarcinoma; Stage II Pancreatic Cancer AJCC v8; Stage IIA Pancreatic Cancer AJCC v8; Stage IIB Pancreatic Cancer AJCC v8; Stage III Pancreatic Cancer AJCC v8; Stage IV Pancreatic Cancer AJCC v8; Unresectable Pancreatic Ductal Adenocarcinoma |
Flemming Forsberg |
2021-12-06 | PHASE1; PHASE2 |
| NCT04390399 | ACTIVE_NOT_RECRUITING | Pancreatic Cancer |
ImmunityBio, Inc. |
2020-07-21 | PHASE2 |
| NCT05859750 | RECRUITING | Pancreatic Cancer |
Akeso |
2023-05-25 | PHASE2 |
| NCT06475326 | UNKNOWN | Pancreatic Cancer |
Fudan University |
2024-06-05 | PHASE2 |
| NCT06493760 | RECRUITING | Metastatic Colorectal Cancer |
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. |
2024-09-03 | PHASE2 |
| NCT05015621 | UNKNOWN | Advanced Neuroendocrine Carcinoma |
Hutchison Medipharma Limited |
2021-09-18 | PHASE3 |
| NCT04141995 | TERMINATED | Pancreas Cancer; Adenocarcinoma of the Pancreas |
University of Nebraska |
2021-02-12 | PHASE2 |
| NCT04363801 | TERMINATED | Gastric Cancer; Gastric Adenocarcinoma; GastroEsophageal Cancer |
Leap Therapeutics, Inc. |
2020-07-29 | PHASE2 |
| NCT04245865 | ACTIVE_NOT_RECRUITING | Colorectal Cancer Metastatic |
Vejle Hospital |
2020-06-26 | PHASE2 |
| NCT00059930 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
Memorial Sloan Kettering Cancer Center |
2003-01 | PHASE1 |
| NCT04535401 | ACTIVE_NOT_RECRUITING | Advanced Colorectal Carcinoma; Advanced Digestive System Carcinoma; Advanced Gastric Carcinoma; Advanced Gastroesophageal Junction Adenocarcinoma; Clinical Stage III Gastric Cancer AJCC v8; Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8; Clinical Stage IV Gastric Cancer AJCC v8; Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8; Metastatic Colorectal Carcinoma; Metastatic Digestive System Carcinoma; Metastatic Gastric Carcinoma; Metastatic Gastroesophageal Junction Adenocarcinoma; Stage III Colorectal Cancer AJCC v8; Stage IV Colorectal Cancer AJCC v8 |
National Cancer Institute (NCI) |
2021-08-13 | PHASE1 |
| NCT02912559 | ACTIVE_NOT_RECRUITING | Colon Adenocarcinoma; DNA Repair Disorder; Lynch Syndrome; Stage III Colon Cancer AJCC v8 |
National Cancer Institute (NCI) |
2017-10-16 | PHASE3 |
| NCT05751850 | UNKNOWN | First-line Treatment of Advanced Pancreatic Cancer |
Jiangsu HengRui Medicine Co., Ltd. |
2023-06-13 | PHASE3 |
| NCT06345300 | UNKNOWN | Borderline Resectable Pancreatic Cancer |
Cancer Institute and Hospital, Chinese Academy of Medical Sciences |
2024-03-10 | PHASE2 |
| NCT04539808 | ACTIVE_NOT_RECRUITING | Pancreatic Adenocarcinoma; Stage 0 Pancreatic Cancer American Joint Committee on Cancer v8; Stage I Pancreatic Cancer American Joint Committee on Cancer v8; Stage III Pancreatic Cancer American Joint Committee on Cancer v8; Stage IV Pancreatic Cancer American Joint Committee on Cancer v8 |
OHSU Knight Cancer Institute |
2021-05-27 | PHASE2 |
| NCT04595864 | RECRUITING | Hepatocellular Carcinoma; Liver Transplantation |
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School |
2020-11-01 | PHASE3 |
| NCT04562558 | ACTIVE_NOT_RECRUITING | Gestational Trophoblastic Tumor; Gestational Trophoblastic Neoplasia; Stage I Gestational Trophoblastic Tumor; Stage II Gestational Trophoblastic Tumor; Stage III Gestational Trophoblastic Tumor; Invasive Mole; Choriocarcinoma |
xiang yang |
2020-09-29 | |
| NCT02578368 | COMPLETED | Gastric Cancer |
Krankenhaus Nordwest |
2016-02 | PHASE3 |
| NCT02138617 | COMPLETED | Colon Cancer |
UNC Lineberger Comprehensive Cancer Center |
2014-05-06 | PHASE2 |
| NCT05032183 | TERMINATED | Recurrent Adult Lymphoblastic Lymphoma; Recurrent B Acute Lymphoblastic Leukemia; Recurrent T Acute Lymphoblastic Leukemia; Refractory B Acute Lymphoblastic Leukemia; Refractory Lymphoblastic Lymphoma; Refractory T Acute Lymphoblastic Leukemia |
M.D. Anderson Cancer Center |
2022-02-17 | PHASE1; PHASE2 |
| NCT04094688 | ACTIVE_NOT_RECRUITING | Colorectal Adenocarcinoma |
Alliance for Clinical Trials in Oncology |
2019-10-29 | PHASE3 |
| NCT06094140 | ACTIVE_NOT_RECRUITING | Pancreatic Cancer |
Australasian Gastro-Intestinal Trials Group |
2022-05-20 | PHASE2 |
| NCT04796948 | COMPLETED | Advanced Pancreatic Cancer |
Jiangsu HengRui Medicine Co., Ltd. |
2021-04-08 | PHASE1 |
| NCT05192889 | ACTIVE_NOT_RECRUITING | Refractory Acute Lymphoblastic Leukemia; Relapsed Acute Lymphoblastic Leukemia |
St. Jude Children's Research Hospital |
2022-08-25 | PHASE1; PHASE2 |
| NCT03641976 | UNKNOWN | Unresectable Metastatic Right-sided Colon Cancer Starting First-line Combination Chemotherapy; Unresectable Metastatic Right-sided Colon Cancer, Stage IV |
Yonsei University |
2019-01-03 | PHASE2 |
| NCT03970252 | COMPLETED | Borderline Resectable Pancreatic Adenocarcinoma; Resectable Pancreatic Ductal Adenocarcinoma |
Jonsson Comprehensive Cancer Center |
2019-07-24 | EARLY_PHASE1 |
| NCT05640726 | UNKNOWN | Rectal Cancer |
Fujian Cancer Hospital |
2023-05-01 | PHASE2 |
| NCT02720068 | COMPLETED | Neoplasms |
Merck Sharp & Dohme LLC |
2016-05-02 | PHASE1 |
| NCT03221426 | COMPLETED | Gastric Cancer; Gastroesophageal Junction Cancer |
Merck Sharp & Dohme LLC |
2017-10-09 | PHASE3 |
| NCT04882241 | COMPLETED | Gastric Cancer; Gastroesophageal Junction Cancer |
Merck Sharp & Dohme LLC |
2020-07-29 | PHASE3 |
| NCT05615012 | COMPLETED | Healthy Participants |
Bristol-Myers Squibb |
2022-11-11 | PHASE1 |
| NCT03127124 | WITHDRAWN | Pancreatic Adenocarcinoma Metastatic |
NantPharma, LLC |
2018-02-27 | PHASE1; PHASE2 |
| NCT05480280 | UNKNOWN | Advanced/Metastatic Colorectal Cancer |
Sixth Affiliated Hospital, Sun Yat-sen University |
2022-07-20 | PHASE2 |
| NCT05546411 | TERMINATED | Pancreatic Cancer; Resectable Pancreatic Cancer; Borderline Resectable Pancreatic Adenocarcinoma; Pancreatic Adenocarcinoma |
Kimberly Perez, MD |
2023-01-06 | PHASE2 |
| NCT05148195 | TERMINATED | Advanced Solid Tumor |
Jiangsu Simcere Pharmaceutical Co., Ltd. |
2021-12-22 | PHASE2 |
| NCT05417386 | TERMINATED | Pancreas Cancer; Metastatic Pancreatic Cancer; Metastatic Pancreatic Adenocarcinoma |
Colin D. Weekes, M.D., PhD |
2022-08-09 | PHASE1 |
| NCT04068103 | ACTIVE_NOT_RECRUITING | Colon Adenocarcinoma; Stage IIA Colon Cancer AJCC v8 |
NRG Oncology |
2019-12-16 | PHASE2; PHASE3 |
| NCT02003222 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative |
National Cancer Institute (NCI) |
2014-05-19 | PHASE3 |
| NCT04164069 | COMPLETED | Advanced Colorectal Carcinoma; Metastatic Colorectal Carcinoma; Stage IV Colorectal Cancer AJCC v8; Stage IVA Colorectal Cancer AJCC v8; Stage IVB Colorectal Cancer AJCC v8; Stage IVC Colorectal Cancer AJCC v8; Stage II Colon Cancer; Stage II Rectal Cancer; Stage III Colon Cancer; Stage III Rectal Cancer; Esophageal Cancer; Pancreatic Cancer; Bile Duct Cancer; Gastric Cancer; Gall Bladder Cancer; Small Bowel Adenocarcinoma |
Anne Noonan |
2020-09-02 | PHASE1 |
| NCT04761614 | COMPLETED | Metastatic Colorectal Carcinoma; Stage IV Colorectal Cancer AJCC v8; Stage IVA Colorectal Cancer AJCC v8; Stage IVB Colorectal Cancer AJCC v8; Stage IVC Colorectal Cancer AJCC v8 |
Ning Jin |
2021-04-02 | PHASE1 |
| NCT02883049 | COMPLETED | B Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia, BCR-ABL1-Like; Central Nervous System Leukemia; Testicular Leukemia |
National Cancer Institute (NCI) |
2012-02-29 | PHASE3 |
| NCT03192618 | UNKNOWN | Hepatocellular Carcinoma |
Sun Yat-sen University |
2017-07-01 | PHASE3 |
| NCT03192644 | UNKNOWN | Hepatocellular Carcinoma |
Sun Yat-sen University |
2017-07-01 | PHASE3 |
| NCT04155671 | UNKNOWN | Gastric Cancer |
Fujian Cancer Hospital |
2019-12-01 | PHASE2 |
| NCT04097444 | UNKNOWN | Metastatic Colorectal Cancer |
Chugai Pharmaceutical |
2019-10-11 | PHASE2 |
| NCT02047474 | COMPLETED | Acinar Cell Adenocarcinoma of the Pancreas; Duct Cell Adenocarcinoma of the Pancreas; Stage I Pancreatic Cancer; Stage IIA Pancreatic Cancer; Stage IIB Pancreatic Cancer |
Yale University |
2014-03-25 | PHASE2 |
| NCT04083235 | COMPLETED | Metastatic Adenocarcinoma of the Pancreas |
Ipsen |
2020-02-11 | PHASE3 |
| NCT02735239 | COMPLETED | Esophageal Cancer |
Ludwig Institute for Cancer Research |
2016-06-24 | PHASE1; PHASE2 |
| NCT02553460 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia |
St. Jude Children's Research Hospital |
2016-01-29 | PHASE1; PHASE2 |
| NCT02037048 | UNKNOWN | Adenocarcinoma of the Esophagus; Adenocarcinoma of the Gastroesophageal Junction; Adenocarcinoma of the Gastric Cardia; Stage IIIA Esophageal Cancer; Stage IIIB Esophageal Cancer; Stage IIIC Esophageal Cancer |
Case Comprehensive Cancer Center |
2014-02-10 | PHASE2 |
| NCT04121039 | UNKNOWN | Gastric Adenocarcinoma; Advanced Cancer |
Fujian Cancer Hospital |
2019-12 | PHASE2 |
| NCT01897454 | TERMINATED | Pancreatic Adenocarcinoma; Stage IIA Pancreatic Cancer; Stage IIB Pancreatic Cancer; Stage III Pancreatic Cancer |
Albert Einstein College of Medicine |
2012-01-27 | PHASE2 |
| NCT03374254 | COMPLETED | Metastatic Colorectal Cancer |
Merck Sharp & Dohme LLC |
2018-02-16 | PHASE1 |
| NCT03665441 | COMPLETED | Pancreatic Adenocarcinoma |
ERYtech Pharma |
2018-09-15 | PHASE3 |
| NCT03050814 | TERMINATED | Colorectal Tumors; Colorectal Neoplasms; Colorectal Carcinoma; Colorectal Adenocarcinoma; Colorectal Cancer |
National Cancer Institute (NCI) |
2017-04-05 | PHASE2 |
| NCT02730546 | COMPLETED | Gastric Cardia Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma; Stage IB Gastric Cancer AJCC v7; Stage II Gastric Cancer AJCC v7; Stage IIA Gastric Cancer AJCC v7; Stage IIB Gastric Cancer AJCC v7; Stage IIIA Gastric Cancer AJCC v7; Stage IIIB Gastric Cancer AJCC v7 |
Mayo Clinic |
2016-06-24 | PHASE1; PHASE2 |
| NCT02101853 | ACTIVE_NOT_RECRUITING | Recurrent B Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2014-12-17 | PHASE3 |
| NCT02620865 | COMPLETED | Metastatic Pancreatic Adenocarcinoma; Recurrent Pancreatic Carcinoma; Stage III Pancreatic Cancer; Stage IV Pancreatic Cancer |
Barbara Ann Karmanos Cancer Institute |
2015-12 | PHASE1; PHASE2 |
| NCT03518112 | TERMINATED | Philadelphia Chromosome Negative; Recurrent B Acute Lymphoblastic Leukemia; Refractory B Acute Lymphoblastic Leukemia |
M.D. Anderson Cancer Center |
2018-04-18 | PHASE2 |
| NCT03337087 | UNKNOWN | Metastatic Biliary Tract Carcinoma; Metastatic Colorectal Carcinoma; Metastatic Gastroesophageal Junction Adenocarcinoma; Metastatic Malignant Digestive System Neoplasm; Metastatic Pancreatic Adenocarcinoma; Stage IV Colorectal Cancer AJCC v7; Stage IV Pancreatic Cancer AJCC v6 and v7; Stage IVA Colorectal Cancer AJCC v7; Stage IVB Colorectal Cancer AJCC v7 |
Academic and Community Cancer Research United |
2018-11-02 | PHASE1; PHASE2 |
| NCT03414983 | COMPLETED | Colorectal Cancer |
Bristol-Myers Squibb |
2018-02-20 | PHASE2; PHASE3 |
| NCT02420717 | TERMINATED | Recurrent B Acute Lymphoblastic Leukemia; Recurrent Ph-Like Acute Lymphoblastic Leukemia; Refractory B Acute Lymphoblastic Leukemia; Refractory Ph-Like Acute Lymphoblastic Leukemia |
M.D. Anderson Cancer Center |
2015-07-15 | PHASE2 |
| NCT02870036 | UNKNOWN | Advanced Solid Tumor; Advanced/Metastatic Colorectal Cancer |
Haihe Biopharma Co., Ltd. |
2016-10 | PHASE1 |
| NCT00550992 | UNKNOWN | Leukemia |
Dutch Childhood Oncology Group |
2006-01 | |
| NCT04060030 | Recruiting | Autism Spectrum Disorder|Language Disorders |
Southwest Autism Research & Resource Center|Autism Speaks|State University of New York - Downstate Medical Center |
2020-10-08 | Phase 2 |
| NCT02828358 | COMPLETED | Acute Leukemia of Ambiguous Lineage; B Acute Lymphoblastic Leukemia; Mixed Phenotype Acute Leukemia |
National Cancer Institute (NCI) |
2017-04-01 | PHASE2 |
| NCT03387085 | TERMINATED | Triple Negative Breast Cancer |
ImmunityBio, Inc. |
2018-03-19 | PHASE1; PHASE2 |
| NCT04060017 | Recruiting | Autism Spectrum Disorder|Language Disorders |
Southwest Autism Research & Resource Center|State University of New York - Downstate Medical Center|United States Department of Defense |
2020-09-22 | Phase 2 |
| NCT03554109 | WITHDRAWN | Triple Negative Breast Cancer (TNBC) |
ImmunityBio, Inc. |
2018-09 | PHASE2 |
| NCT02921256 | COMPLETED | Rectal Adenocarcinoma; Stage II Rectal Cancer AJCC v7; Stage III Rectal Cancer AJCC v7 |
National Cancer Institute (NCI) |
2017-01-11 | PHASE2 |
| NCT03488225 | TERMINATED | Acute Lymphoblastic Leukemia in Remission; B Acute Lymphoblastic Leukemia; B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative |
M.D. Anderson Cancer Center |
2018-03-28 | PHASE2 |
| NCT02112916 | ACTIVE_NOT_RECRUITING | Adult T Acute Lymphoblastic Leukemia; Ann Arbor Stage II Adult Lymphoblastic Lymphoma; Ann Arbor Stage II Childhood Lymphoblastic Lymphoma; Ann Arbor Stage III Adult Lymphoblastic Lymphoma; Ann Arbor Stage III Childhood Lymphoblastic Lymphoma; Ann Arbor Stage IV Adult Lymphoblastic Lymphoma; Ann Arbor Stage IV Childhood Lymphoblastic Lymphoma; Childhood T Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2014-10-04 | PHASE3 |
| NCT03563144 | WITHDRAWN | Metastatic Pancreatic Cancer |
ImmunityBio, Inc. |
2018-08 | PHASE2 |
| NCT03788174 | UNKNOWN | Gastric Adenocarcinoma |
Fujian Cancer Hospital |
2019-02-01 | PHASE2 |
| NCT02658214 | COMPLETED | Small Cell Lung Carcinoma; Carcinoma, Squamous Cell of Head and Neck; Stomach Neoplasms; Triple Negative Breast Neoplasms; Ovarian Neoplasms; Fallopian Tube Neoplasms; Peritoneal Neoplasms; Esophagogastric Junction Neoplasms; Carcinoma, Pancreatic Ductal; Esophageal Squamous Cell Carcinoma |
AstraZeneca |
2016-04-28 | PHASE1 |
| NCT03300609 | TERMINATED | Colorectal Adenocarcinoma; RAS Wild Type; Stage III Colorectal Cancer AJCC v7; Stage IIIA Colorectal Cancer AJCC v7; Stage IIIB Colorectal Cancer AJCC v7; Stage IIIC Colorectal Cancer AJCC v7; Stage IV Colorectal Cancer AJCC v7; Stage IVA Colorectal Cancer AJCC v7; Stage IVB Colorectal Cancer AJCC v7 |
University of Southern California |
2018-02-27 | PHASE3 |
| NCT03707639 | UNKNOWN | Gastric Adenocarcinoma |
Fujian Cancer Hospital |
2018-11 | PHASE2 |
| NCT00267865 | COMPLETED | AIDS-Related-Primary Central Nervous System Lymphoma |
National Cancer Institute (NCI) |
2006-09-14 | PHASE2 |
| NCT03110510 | WITHDRAWN | Biliary Tract Cancer |
Samsung Medical Center |
2019-09-06 | PHASE2 |
| NCT03563170 | WITHDRAWN | Hepatocellular Carcinoma Non-resectable; Hepatocellular Carcinoma Recurrent |
ImmunityBio, Inc. |
2018-05-25 | PHASE1; PHASE2 |
| NCT02705300 | COMPLETED | Colorectal Cancer |
Vejle Hospital |
2016-05-06 | PHASE2 |
| NCT02890355 | COMPLETED | Metastatic Pancreatic Adenocarcinoma; Recurrent Pancreatic Carcinoma; Stage IV Pancreatic Cancer AJCC v6 and v7 |
National Cancer Institute (NCI) |
2016-10-27 | PHASE2 |
| NCT03563157 | TERMINATED | Colorectal Cancer Metastatic; mCRC |
ImmunityBio, Inc. |
2018-09-28 | PHASE1; PHASE2 |
| NCT03586869 | TERMINATED | Pancreatic Cancer |
ImmunityBio, Inc. |
2018-07-17 | PHASE1; PHASE2 |
| NCT03387111 | TERMINATED | Squamous Cell Carcinoma |
ImmunityBio, Inc. |
2018-01-09 | PHASE1; PHASE2 |
| NCT01959139 | COMPLETED | Metastatic Pancreatic Adenocarcinoma |
SWOG Cancer Research Network |
2014-01-23 | PHASE1; PHASE2 |
| NCT01190930 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Lymphoblastic Lymphoma; Ann Arbor Stage I B Lymphoblastic Lymphoma; Ann Arbor Stage II B Lymphoblastic Lymphoma; Childhood B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Childhood B Lymphoblastic Lymphoma; Down Syndrome; Hypodiploid B Acute Lymphoblastic Leukemia; Philadelphia Chromosome Positive |
Children's Oncology Group |
2010-08-11 | PHASE3 |
| NCT03197584 | WITHDRAWN | Ovarian Cancer |
ImmunityBio, Inc. |
2017-12 | PHASE1; PHASE2 |
| NCT03167177 | WITHDRAWN | Melanoma |
ImmunityBio, Inc. |
2017-12 | PHASE1; PHASE2 |
| NCT03167164 | WITHDRAWN | Merkel Cell Carcinoma |
ImmunityBio, Inc. |
2017-12 | PHASE1; PHASE2 |
| NCT03175666 | WITHDRAWN | Triple Negative Breast Cancer |
ImmunityBio, Inc. |
2017-12 | PHASE1; PHASE2 |
| NCT03169764 | WITHDRAWN | Head and Neck Squamous Cell Carcinoma |
ImmunityBio, Inc. |
2017-12 | PHASE1; PHASE2 |
| NCT03197571 | WITHDRAWN | Urothelial Carcinoma |
ImmunityBio, Inc. |
2017-12 | PHASE1; PHASE2 |
| NCT03169790 | WITHDRAWN | Non Hodgkin Lymphoma |
ImmunityBio, Inc. |
2017-12 | PHASE1; PHASE2 |
| NCT03169738 | WITHDRAWN | Non-small Cell Lung Cancer |
ImmunityBio, Inc. |
2018-02 | PHASE1; PHASE2 |
| NCT03169777 | WITHDRAWN | Colorectal Cancer |
ImmunityBio, Inc. |
2018-08 | PHASE1; PHASE2 |
| NCT03244774 | UNKNOWN | Gastric Adenocarcinoma |
Fujian Cancer Hospital |
2018-01-01 | PHASE1 |
| NCT02620800 | COMPLETED | Metastatic Pancreas Adenocarcinoma |
Celgene |
2016-01-18 | PHASE1 |
| NCT02319018 | COMPLETED | Malignant Digestive System Neoplasm |
National Cancer Institute (NCI) |
2015-08-27 | PHASE1 |
| NCT03387098 | TERMINATED | Pancreatic Cancer |
ImmunityBio, Inc. |
2017-12-28 | PHASE1; PHASE2 |
| NCT03329248 | TERMINATED | Pancreatic Cancer |
ImmunityBio, Inc. |
2017-11-06 | PHASE1; PHASE2 |
| NCT01814501 | COMPLETED | Mucinous Adenocarcinoma of the Colon; Mucinous Adenocarcinoma of the Rectum; Recurrent Colon Cancer; Recurrent Rectal Cancer; Signet Ring Adenocarcinoma of the Colon; Signet Ring Adenocarcinoma of the Rectum; Stage IV Colon Cancer; Stage IV Rectal Cancer |
John Hays |
2013-02-01 | PHASE2 |
| NCT01666730 | COMPLETED | Acinar Cell Adenocarcinoma of the Pancreas; Duct Cell Adenocarcinoma of the Pancreas; Recurrent Pancreatic Cancer; Stage IV Pancreatic Cancer |
Case Comprehensive Cancer Center |
2013-02-21 | PHASE2 |
| NCT01964755 | TERMINATED | Epstein Barr Virus Associated Non Hodgkin's Lymphoma; Epstein Barr Virus Associated Hodgkin's Lymphoma; Post-Transplant Lymphoproliferative Disease |
University of Miami |
2009-04-21 | PHASE2 |
| NCT01535053 | COMPLETED | Choriocarcinoma; FIGO Stage I Gestational Trophoblastic Tumor; FIGO Stage II Gestational Trophoblastic Tumor; FIGO Stage III Gestational Trophoblastic Tumor; Hydatidiform Mole |
GOG Foundation |
2012-06-18 | PHASE3 |
| NCT02270606 | COMPLETED | Mucinous Adenocarcinoma of the Rectum; Recurrent Rectal Cancer; Signet Ring Adenocarcinoma of the Rectum; Rectal Adenocarcinoma; Stage IIA Rectal Cancer; Stage IIB Rectal Cancer; Stage IIC Rectal Cancer; Stage IIIA Rectal Cancer; Stage IIIB Rectal Cancer; Stage IIIC Rectal Cancer |
Virginia Commonwealth University |
2014-12-04 | PHASE1 |
| NCT02845908 | COMPLETED | Malignant Neoplasm of Stomach Stage IV |
Fujian Cancer Hospital |
2015-11 | PHASE2 |
| NCT02779283 | COMPLETED | Acute Lymphoblastic Leukemia; Acute Myeloid Leukemia |
OHSU Knight Cancer Institute |
2016-01-13 | PHASE1 |
| NCT02676323 | TERMINATED | Acute Myeloid Leukemia; Myelodysplastic Syndrome |
St. Jude Children's Research Hospital |
2016-05-03 | PHASE1 |
| NCT01959672 | COMPLETED | Pancreatic Adenocarcinoma; Resectable Pancreatic Carcinoma; Stage I Pancreatic Cancer; Stage IA Pancreatic Cancer; Stage IB Pancreatic Cancer; Stage II Pancreatic Cancer; Stage IIA Pancreatic Cancer; Stage IIB Pancreatic Cancer; Stage III Pancreatic Cancer |
University of Nebraska |
2013-09-06 | PHASE2 |
| NCT02817425 | UNKNOWN | Gastric Cancer |
LanZhou University |
2013-05 | PHASE2; PHASE3 |
| NCT02896907 | COMPLETED | Pancreatic Adenocarcinoma; Recurrent Pancreatic Carcinoma; Stage III Pancreatic Cancer; Stage IV Pancreatic Cancer; Unresectable Pancreatic Carcinoma |
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
2016-10-18 | EARLY_PHASE1 |
| NCT01871571 | TERMINATED | Mucinous Adenocarcinoma of the Rectum; Signet Ring Adenocarcinoma of the Rectum; Stage IIA Rectal Cancer; Stage IIB Rectal Cancer; Stage IIC Rectal Cancer; Stage IIIA Rectal Cancer; Stage IIIB Rectal Cancer; Stage IIIC Rectal Cancer |
University of Southern California |
2013-08-02 | PHASE2 |
| NCT01498289 | COMPLETED | Adenocarcinoma of the Gastroesophageal Junction; Esophageal Cancer; Gastric Cancer |
SWOG Cancer Research Network |
2012-02 | PHASE2 |
| NCT02041481 | COMPLETED | Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer |
City of Hope Medical Center |
2014-06 | PHASE1 |
| NCT02785146 | UNKNOWN | Colorectal Cancer |
Sixth Affiliated Hospital, Sun Yat-sen University |
2016-06 | PHASE3 |
| NCT02293109 | COMPLETED | Contiguous Stage II Adult Lymphoblastic Lymphoma; Noncontiguous Stage II Adult Lymphoblastic Lymphoma; Stage I Adult Lymphoblastic Lymphoma; Stage III Adult Lymphoblastic Lymphoma; Stage IV Adult Lymphoblastic Lymphoma; Untreated Adult Acute Lymphoblastic Leukemia |
Mehrdad Abedi, MD |
2015-12-17 | PHASE1 |
| NCT02333188 | COMPLETED | Adenocarcinoma of Unknown Primary; Adult Cholangiocarcinoma; Gallbladder Carcinoma; Gastric Adenocarcinoma; Malignant Gastrointestinal Neoplasm; Metastatic Pancreatic Adenocarcinoma; Pancreatic Adenocarcinoma; Stage III Ampulla of Vater Cancer; Stage III Pancreatic Cancer; Stage IIIA Gallbladder Cancer; Stage IIIA Gastric Cancer; Stage IIIB Gallbladder Cancer; Stage IIIB Gastric Cancer; Stage IV Ampulla of Vater Cancer; Stage IV Gallbladder Cancer; Stage IV Gastric Cancer; Stage IV Pancreatic Cancer |
University of Chicago |
2014-12 | PHASE1 |
| NCT03136406 | TERMINATED | Pancreatic Cancer |
ImmunityBio, Inc. |
2017-08-11 | PHASE1; PHASE2 |
| NCT03258762 | COMPLETED | Toxoplasmosis |
GlaxoSmithKline |
2017-09-25 | PHASE1 |
| NCT01256398 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 |
National Cancer Institute (NCI) |
2010-12-14 | PHASE2 |
| NCT02413853 | WITHDRAWN | Colorectal Adenocarcinoma; Stage IVA Colorectal Cancer; Stage IVB Colorectal Cancer |
University of Southern California |
2015-11 | PHASE2 |
| NCT02015819 | COMPLETED | Adult Anaplastic Astrocytoma; Adult Anaplastic Oligodendroglioma; Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Recurrent Adult Brain Tumor; Anaplastic Oligoastrocytoma |
City of Hope Medical Center |
2014-10-07 | PHASE1 |
| NCT00557193 | COMPLETED | Acute Lymphoblastic Leukemia; Acute Undifferentiated Leukemia; Childhood T Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2008-01-15 | PHASE3 |
| NCT00408005 | COMPLETED | T Acute Lymphoblastic Leukemia; T Lymphoblastic Lymphoma |
National Cancer Institute (NCI) |
2007-01-30 | PHASE3 |
| NCT02508077 | TERMINATED | Recurrent Colorectal Carcinoma; Stage IVA Colorectal Cancer; Stage IVB Colorectal Cancer |
City of Hope Medical Center |
2016-02-16 | PHASE2 |
| NCT02235324 | WITHDRAWN | Mucinous Adenocarcinoma of the Colon; Mucinous Adenocarcinoma of the Rectum; Recurrent Colon Cancer; Recurrent Rectal Cancer; Signet Ring Adenocarcinoma of the Colon; Signet Ring Adenocarcinoma of the Rectum; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer |
University of Southern California |
2015-03 | PHASE2 |
| NCT01835041 | COMPLETED | Acinar Cell Adenocarcinoma of the Pancreas; Duct Cell Adenocarcinoma of the Pancreas; Recurrent Pancreatic Cancer; Stage IV Pancreatic Cancer |
Wake Forest University Health Sciences |
2013-04 | PHASE1 |
| NCT00544414 | COMPLETED | Head and Neck Cancer |
City of Hope Medical Center |
2000-06-07 | PHASE2 |
| NCT01383343 | COMPLETED | Recurrent Colon Carcinoma; Recurrent Rectal Carcinoma; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer |
National Cancer Institute (NCI) |
2011-08 | PHASE1 |
| NCT02246049 | COMPLETED | Colorectal Neoplasms |
EPS Corporation |
2014-05 | PHASE2 |
| NCT01987102 | COMPLETED | Osteosarcoma |
Isofol Medical AB |
2013-12 | PHASE1; PHASE2 |
| NCT02042443 | COMPLETED | Adult Cholangiocarcinoma; Advanced Adult Hepatocellular Carcinoma; BCLC Stage C Adult Hepatocellular Carcinoma; BCLC Stage D Adult Hepatocellular Carcinoma; Hilar Cholangiocarcinoma; Localized Non-Resectable Adult Liver Carcinoma; Recurrent Adult Liver Carcinoma; Recurrent Childhood Liver Cancer; Recurrent Extrahepatic Bile Duct Carcinoma; Recurrent Gallbladder Carcinoma; Stage II Gallbladder Cancer; Stage III Childhood Hepatocellular Carcinoma; Stage IIIA Gallbladder Cancer; Stage IIIB Gallbladder Cancer; Stage IV Childhood Hepatocellular Carcinoma; Stage IV Distal Bile Duct Cancer; Stage IVA Gallbladder Cancer; Stage IVB Gallbladder Cancer; Unresectable Extrahepatic Bile Duct Carcinoma |
National Cancer Institute (NCI) |
2014-02 | PHASE2 |
| NCT00336024 | COMPLETED | Anaplastic Medulloblastoma; Medulloblastoma; Supratentorial Embryonal Tumor, Not Otherwise Specified; Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor |
Children's Oncology Group |
2007-10-22 | PHASE3 |
| NCT01758666 | UNKNOWN | Osteosarcoma |
Tianjin Medical University Cancer Institute and Hospital |
2012-09 | |
| NCT01533324 | UNKNOWN | Carcinoma; Liver Diseases; Hepatocellular Carcinoma |
Second Military Medical University |
2011-11 | PHASE2 |
| NCT00653068 | COMPLETED | Childhood Atypical Teratoid/Rhabdoid Tumor |
Children's Oncology Group |
2009-02-10 | PHASE3 |
| NCT01643499 | COMPLETED | Acinar Cell Adenocarcinoma of the Pancreas; Adenocarcinoma of the Gallbladder; Adenocarcinoma of Unknown Primary; Adult Primary Cholangiocellular Carcinoma; Advanced Adult Primary Liver Cancer; Cholangiocarcinoma of the Extrahepatic Bile Duct; Cholangiocarcinoma of the Gallbladder; Diffuse Adenocarcinoma of the Stomach; Duct Cell Adenocarcinoma of the Pancreas; Intestinal Adenocarcinoma of the Stomach; Localized Unresectable Adult Primary Liver Cancer; Metastatic Carcinoma of Unknown Primary; Metastatic Extrahepatic Bile Duct Cancer; Mixed Adenocarcinoma of the Stomach; Mucinous Adenocarcinoma of the Colon; Mucinous Adenocarcinoma of the Rectum; Newly Diagnosed Carcinoma of Unknown Primary; Signet Ring Adenocarcinoma of the Colon; Signet Ring Adenocarcinoma of the Rectum; Stage III Pancreatic Cancer; Stage IIIA Colon Cancer; Stage IIIA Gallbladder Cancer; Stage IIIA Gastric Cancer; Stage IIIA Rectal Cancer; Stage IIIB Colon Cancer; Stage IIIB Gallbladder Cancer; Stage IIIB Gastric Cancer; Stage IIIB Rectal Cancer; Stage IIIC Colon Cancer; Stage IIIC Gastric Cancer; Stage IIIC Rectal Cancer; Stage IV Gastric Cancer; Stage IV Pancreatic Cancer; Stage IVA Colon Cancer; Stage IVA Gallbladder Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Gallbladder Cancer; Stage IVB Rectal Cancer; Unresectable Extrahepatic Bile Duct Cancer |
University of Chicago |
2012-03-26 | PHASE1 |
| NCT02573220 | WITHDRAWN | Stage IVA Colorectal Cancer; Stage IVB Colorectal Cancer |
University of Chicago |
2015-06 | PHASE1 |
| NCT01364376 | COMPLETED | Stomach Neoplasms |
Zhejiang University |
2011-06 | |
| NCT01231399 | COMPLETED | Adenocarcinoma of the Esophagus; Adenocarcinoma of the Gastroesophageal Junction; Diffuse Adenocarcinoma of the Stomach; Intestinal Adenocarcinoma of the Stomach; Mixed Adenocarcinoma of the Stomach; Recurrent Esophageal Cancer; Recurrent Gastric Cancer; Stage IV Esophageal Cancer; Stage IV Gastric Cancer |
City of Hope Medical Center |
2012-02 | PHASE1; PHASE2 |
| NCT00792948 | ACTIVE_NOT_RECRUITING | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Adult L1 Acute Lymphoblastic Leukemia; Adult L2 Acute Lymphoblastic Leukemia; Adult T Acute Lymphoblastic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2009-09-01 | PHASE2 |
| NCT02500940 | UNKNOWN | Nasopharyngeal Carcinoma |
Taichung Veterans General Hospital |
2015-05 | PHASE3 |
| NCT00381680 | COMPLETED | B-cell Childhood Acute Lymphoblastic Leukemia; L1 Childhood Acute Lymphoblastic Leukemia; L2 Childhood Acute Lymphoblastic Leukemia; Intermediate Risk Recurrent Childhood Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2007-03 | PHASE3 |
| NCT02345460 | TERMINATED | Pancreatic Adenocarcinoma; Poorly Differentiated Malignant Neoplasm; Resectable Pancreatic Cancer; Stage IA Pancreatic Cancer; Stage IB Pancreatic Cancer; Stage IIA Pancreatic Cancer; Stage IIB Pancreatic Cancer; Stage III Pancreatic Cancer; Undifferentiated Pancreatic Carcinoma |
Case Comprehensive Cancer Center |
2015-09 | PHASE2 |
| NCT01412879 | COMPLETED | Lymphoma |
SWOG Cancer Research Network |
2011-11 | PHASE2 |
| NCT00952029 | COMPLETED | Colorectal Cancer |
Federation Francophone de Cancerologie Digestive |
2010-03 | PHASE2; PHASE3 |
| NCT00769405 | COMPLETED | Colorectal Cancer; Primary Peritoneal Cavity Cancer |
UNICANCER |
2008-02 | PHASE3 |
| NCT02392377 | TERMINATED | Stage IB Esophageal Adenocarcinoma; Stage IIA Esophageal Adenocarcinoma; Stage IIB Esophageal Adenocarcinoma; Stage IIIA Esophageal Adenocarcinoma; Stage IIIB Esophageal Adenocarcinoma; Stage IIIC Esophageal Adenocarcinoma |
Case Comprehensive Cancer Center |
2015-02 | PHASE2 |
| NCT01263171 | COMPLETED | Colorectal Cancer |
Cardiff University |
2012-04 | PHASE2 |
| NCT01333033 | COMPLETED | Adenocarcinoma of the Gastroesophageal Junction; Esophageal Cancer |
Alliance for Clinical Trials in Oncology |
2011-07 | PHASE2 |
| NCT01670084 | WITHDRAWN | B-cell Adult Acute Lymphoblastic Leukemia; Blastic Phase Chronic Myelogenous Leukemia; Chronic Myelogenous Leukemia, BCR-ABL1 Positive; Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia; Untreated Adult Acute Lymphoblastic Leukemia |
Mayo Clinic |
2012-12 | PHASE2 |
| NCT00335140 | TERMINATED | Lymphoma |
Eastern Cooperative Oncology Group |
2007-08-23 | PHASE2 |
| NCT00450801 | COMPLETED | Lymphoma |
University of Miami |
2004-04 | PHASE2 |
| NCT03517618 | COMPLETED | Metastatic Colorectal Cancer |
TTY Biopharm |
2014-07-05 | PHASE2 |
| NCT00385970 | UNKNOWN | Colorectal Cancer |
Multicenter Clinical Study Group of Osaka, Colorectal Cancer Treatment Group |
2006-03 | PHASE3 |
| NCT00303628 | TERMINATED | Adenocarcinoma of the Rectum; Stage II Rectal Cancer; Stage III Rectal Cancer |
ECOG-ACRIN Cancer Research Group |
2006-05-11 | PHASE3 |
| NCT02344810 | WITHDRAWN | Adenocarcinoma of the Esophagus; Adenocarcinoma of the Gastroesophageal Junction; Diffuse Adenocarcinoma of the Stomach; Gastrointestinal Cancer; Intestinal Adenocarcinoma of the Stomach; Mixed Adenocarcinoma of the Stomach; Stage IIIA Esophageal Cancer; Stage IIIA Gastric Cancer; Stage IIIB Esophageal Cancer; Stage IIIB Gastric Cancer; Stage IIIC Esophageal Cancer; Stage IIIC Gastric Cancer; Stage IV Esophageal Cancer; Stage IV Gastric Cancer |
Eastern Cooperative Oncology Group |
2015-03-06 | PHASE1; PHASE2 |
| NCT00002525 | TERMINATED | Colorectal Cancer |
ECOG-ACRIN Cancer Research Group |
1993-10-01 | PHASE3 |
| NCT00720109 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1; Childhood B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 |
National Cancer Institute (NCI) |
2008-07-14 | PHASE2; PHASE3 |
| NCT01320683 | TERMINATED | Liver Metastases; Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer |
City of Hope Medical Center |
2011-03 | PHASE2 |
| NCT00482222 | UNKNOWN | Colorectal Cancer; Metastatic Cancer |
University of Southampton |
2007-02 | PHASE3 |
| NCT01238965 | TERMINATED | Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage IV Colon Cancer; Stage IV Rectal Cancer |
University of Southern California |
2010-10 | PHASE1 |
| NCT01279681 | TERMINATED | Cognitive/Functional Effects; Colorectal Cancer; Neurotoxicity |
Alliance for Clinical Trials in Oncology |
2011-01 | PHASE3 |
| NCT01212822 | COMPLETED | Adenocarcinoma of the Esophagus; Adenocarcinoma of the Gastroesophageal Junction; Diffuse Adenocarcinoma of the Stomach; Intestinal Adenocarcinoma of the Stomach; Mixed Adenocarcinoma of the Stomach; Squamous Cell Carcinoma of the Esophagus; Stage IA Esophageal Cancer; Stage IA Gastric Cancer; Stage IB Esophageal Cancer; Stage IB Gastric Cancer; Stage IIA Esophageal Cancer; Stage IIA Gastric Cancer; Stage IIB Esophageal Cancer; Stage IIB Gastric Cancer; Stage IIIA Esophageal Cancer; Stage IIIA Gastric Cancer; Stage IIIB Esophageal Cancer; Stage IIIB Gastric Cancer; Stage IIIC Esophageal Cancer; Stage IIIC Gastric Cancer |
Fox Chase Cancer Center |
2011-04-27 | PHASE2 |
| NCT00873093 | COMPLETED | B-cell Adult Acute Lymphoblastic Leukemia; B-cell Childhood Acute Lymphoblastic Leukemia; Recurrent Adult Acute Lymphoblastic Leukemia; Recurrent Adult Lymphoblastic Lymphoma; Recurrent Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Lymphoblastic Lymphoma; T-cell Adult Acute Lymphoblastic Leukemia; T-cell Childhood Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2009-03 | PHASE2 |
| NCT00400946 | COMPLETED | Drug/Agent Toxicity by Tissue/Organ; Leukemia |
Dana-Farber Cancer Institute |
2005-04 | PHASE3 |
| NCT00957905 | COMPLETED | Recurrent Extragonadal Seminoma; Recurrent Malignant Extragonadal Germ Cell Tumor; Recurrent Malignant Extragonadal Non-Seminomatous Germ Cell Tumor; Recurrent Malignant Testicular Germ Cell Tumor; Recurrent Ovarian Germ Cell Tumor; Stage III Testicular Cancer; Stage IV Extragonadal Non-Seminomatous Germ Cell Tumor; Stage IV Extragonadal Seminoma; Stage IV Ovarian Germ Cell Tumor |
National Cancer Institute (NCI) |
2009-06 | PHASE2 |
| NCT01941173 | WITHDRAWN | Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer |
City of Hope Medical Center |
2014-01 | |
| NCT01375816 | TERMINATED | Colorectal Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2011-05 | PHASE2 |
| NCT01679327 | UNKNOWN | Colorectal Cancer |
Chinese Academy of Medical Sciences |
2012-03 | PHASE2 |
| NCT00002842 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
City of Hope Medical Center |
1994-09 | PHASE2 |
| NCT01229111 | TERMINATED | Adult Primary Cholangiocellular Carcinoma; Advanced Adult Primary Liver Cancer; Cholangiocarcinoma of the Extrahepatic Bile Duct; Cholangiocarcinoma of the Gallbladder; Localized Unresectable Adult Primary Liver Cancer; Periampullary Adenocarcinoma; Recurrent Adult Primary Liver Cancer; Recurrent Extrahepatic Bile Duct Cancer; Recurrent Gallbladder Cancer; Unresectable Extrahepatic Bile Duct Cancer; Unresectable Gallbladder Cancer |
National Cancer Institute (NCI) |
2010-10 | PHASE2 |
| NCT00462501 | COMPLETED | Colorectal Cancer |
Memorial Sloan Kettering Cancer Center |
2007-03 | |
| NCT00317408 | UNKNOWN | Lymphoma |
European Inter-group Cooperation on Childhood and Adolescent Non Hodgkin Lymphoma |
2004-04 | |
| NCT01205022 | COMPLETED | Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage IV Colon Cancer; Stage IV Rectal Cancer |
City of Hope Medical Center |
2011-04 | PHASE1 |
| NCT00103285 | COMPLETED | Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2005-04-11 | PHASE3 |
| NCT00098787 | COMPLETED | Colorectal Cancer |
Eastern Cooperative Oncology Group |
2005-09-08 | PHASE2 |
| NCT00766142 | TERMINATED | Colorectal Cancer; Primary Peritoneal Cavity Cancer |
Institut Bergonié |
2007-05-01 | PHASE2 |
| NCT00096135 | COMPLETED | Leukemia |
Children's Oncology Group |
2004-11 | |
| NCT00541125 | COMPLETED | Colorectal Cancer |
Federation Francophone de Cancerologie Digestive |
2007-11 | PHASE2 |
| NCT00321685 | COMPLETED | Rectal Adenocarcinoma; Stage II Rectal Cancer AJCC v7; Stage III Rectal Cancer AJCC v7 |
National Cancer Institute (NCI) |
2006-07-25 | PHASE2 |
| NCT01068327 | COMPLETED | Adenocarcinoma of the Pancreas; Stage III Pancreatic Cancer |
University of Nebraska |
2007-11-05 | PHASE1 |
| NCT00524186 | TERMINATED | Esophageal Cancer; Gastric Cancer |
Roswell Park Cancer Institute |
2007-05 | PHASE1 |
| NCT01280643 | TERMINATED | Metastatic Colorectal Cancer |
Fox Chase Cancer Center |
2010-03 | |
| NCT00610948 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
UNC Lineberger Comprehensive Cancer Center |
2008-03 | PHASE1 |
| NCT01360086 | COMPLETED | Adenocarcinoma of the Gastroesophageal Junction; Gastric Cancer |
Federation Francophone de Cancerologie Digestive |
2011-06 | PHASE2 |
| NCT00720512 | TERMINATED | Colorectal Cancer |
Gruppo Oncologico del Nord-Ovest |
2008-06 | PHASE3 |
| NCT00591045 | UNKNOWN | Stomach Neoplasms; Gastric Cancer |
Peking University |
2008-01 | PHASE2 |
| NCT00499369 | TERMINATED | Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer |
National Cancer Institute (NCI) |
2007-06 | PHASE3 |
| NCT00079274 | COMPLETED | Adenocarcinoma of the Colon; Stage III Colon Cancer |
National Cancer Institute (NCI) |
2004-02 | PHASE3 |
| NCT01164215 | COMPLETED | Colorectal Cancer; Diarrhea; Neutropenia |
UNC Lineberger Comprehensive Cancer Center |
2010-02 | PHASE1 |
| NCT00262925 | TERMINATED | Recurrent Adult Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2006-06 | PHASE2 |
| NCT00537121 | COMPLETED | Esophageal Cancer; Gastric Cancer; Liver Cancer |
Roswell Park Cancer Institute |
2006-11 | PHASE1 |
| NCT00873275 | COMPLETED | Colorectal Cancer |
City of Hope Medical Center |
2009-03-11 | PHASE1 |
| NCT01473303 | WITHDRAWN | Pancreatic Cancer |
Alliance for Clinical Trials in Oncology |
2012-08 | PHASE1; PHASE2 |
| NCT00052910 | COMPLETED | Esophageal Cancer; Gastric Cancer |
Alliance for Clinical Trials in Oncology |
2002-12 | PHASE3 |
| NCT00660894 | COMPLETED | Colorectal Cancer |
Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan |
2008-04 | PHASE3 |
| NCT00039377 | COMPLETED | Adult Acute Lymphoblastic Leukemia in Remission |
National Cancer Institute (NCI) |
2002-04 | PHASE2 |
| NCT00982592 | COMPLETED | Adenocarcinoma of the Gastroesophageal Junction; Adenocarcinoma of the Stomach; Recurrent Gastric Cancer; Stage IIIA Gastric Cancer; Stage IIIB Gastric Cancer; Stage IIIC Gastric Cancer; Stage IV Gastric Cancer |
National Cancer Institute (NCI) |
2009-09 | PHASE2 |
| NCT00742924 | COMPLETED | Sarcoma |
Children's Oncology Group |
2008-08 | PHASE1 |
| NCT01198548 | TERMINATED | Stage IV Colon Cancer; Stage IV Rectal Cancer |
Roswell Park Cancer Institute |
2010-08 | PHASE2 |
| NCT00303758 | COMPLETED | Pancreatic Cancer |
Federation Francophone de Cancerologie Digestive |
2005-10 | PHASE3 |
| NCT01167725 | TERMINATED | Colorectal Cancer |
Alliance for Clinical Trials in Oncology |
2010-08 | PHASE3 |
| NCT00851045 | COMPLETED | Colorectal Cancer (CRC) |
Bristol-Myers Squibb |
2009-10 | PHASE2 |
| NCT00138177 | COMPLETED | Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage III Colon Cancer; Stage III Rectal Cancer; Stage IV Colon Cancer; Stage IV Rectal Cancer; Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2005-07 | PHASE1 |
| NCT01270438 | WITHDRAWN | Adenocarcinoma of the Colon; Adenocarcinoma of the Rectum; Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer |
National Cancer Institute (NCI) |
2010-12 | PHASE2 |
| NCT01205711 | COMPLETED | Colorectal Cancer |
Cardiff University |
2010-04 | PHASE2 |
| NCT00100841 | COMPLETED | Adenocarcinoma of the Rectum; Mucinous Adenocarcinoma of the Colon; Recurrent Colon Cancer; Recurrent Rectal Cancer; Signet Ring Adenocarcinoma of the Colon; Stage IV Colon Cancer; Stage IV Rectal Cancer |
National Cancer Institute (NCI) |
2004-11 | PHASE2 |
| NCT00392834 | COMPLETED | Lymphoma |
AIDS Malignancy Consortium |
2006-09 | PHASE2 |
| NCT00727831 | COMPLETED | Chemotherapeutic Agent Toxicity; Lymphoma; Mucositis; Neurotoxicity |
University College, London |
2008-07 | PHASE1; PHASE2 |
| NCT00797485 | UNKNOWN | Colorectal Cancer |
Southern Italy Cooperative Oncology Group |
2008-07 | PHASE3 |
| NCT00070213 | COMPLETED | Colorectal Cancer |
Medical Research Council |
2003-09 | PHASE3 |
| NCT00591123 | COMPLETED | Unresectable Adenocarcinoma of the Esophagus; Metastatic Adenocarcinoma of the Esophagus; Unresectable Adenocarcinoma of Gastric Cardia; Metastatic Adenocarcinoma of Gastric Cardia |
Translational Oncology Research International |
2007-12 | PHASE2 |
| NCT00539617 | TERMINATED | Esophageal Cancer |
University of California, San Francisco |
2007-10-05 | PHASE2 |
| NCT00974792 | UNKNOWN | Lymphoma |
Cancer Research UK |
2006-01 | PHASE2 |
| NCT00559676 | COMPLETED | Colorectal Cancer |
Centre Hospital Regional Universitaire de Limoges |
2005-03 | PHASE4 |
| NCT00719797 | COMPLETED | Colorectal Cancer |
Gruppo Oncologico del Nord-Ovest |
2008-07 | PHASE3 |
| NCT00942266 | COMPLETED | Adenocarcinoma of the Colon; Adenocarcinoma of the Rectum; Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage IV Colon Cancer; Stage IV Rectal Cancer |
Roswell Park Cancer Institute |
2009-07 | PHASE2 |
| NCT00559741 | COMPLETED | Colorectal Cancer |
Institut Cancerologie de l'Ouest |
2005-10 | PHASE2 |
| NCT00544349 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
Gustave Roussy, Cancer Campus, Grand Paris |
2006-10 | PHASE2 |
| NCT00098839 | COMPLETED | Recurrent Childhood Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2005-02 | PHASE1; PHASE2 |
| NCT00118261 | COMPLETED | Colorectal Cancer |
Case Comprehensive Cancer Center |
2005-03 | PHASE1 |
| NCT00303771 | COMPLETED | Colorectal Cancer |
Federation Francophone de Cancerologie Digestive |
2003-06 | PHASE3 |
| NCT00514020 | COMPLETED | Gastric Cancer |
Vanderbilt-Ingram Cancer Center |
2007-08 | PHASE2 |
| NCT00075725 | COMPLETED | Acute Lymphoblastic Leukemia; Adult B Acute Lymphoblastic Leukemia; Childhood B Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2003-12-29 | PHASE3 |
| NCT00557102 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
National Cancer Institute, France |
2007-09 | PHASE2 |
| NCT00654160 | COMPLETED | Anal Cancer; Carcinoma of the Appendix; Colorectal Cancer; Esophageal Cancer; Extrahepatic Bile Duct Cancer; Gallbladder Cancer; Gastric Cancer; Gastrointestinal Carcinoid Tumor; Gastrointestinal Stromal Tumor; Liver Cancer; Pancreatic Cancer; Small Intestine Cancer |
Mayo Clinic |
2008-06 | PHASE1 |
| NCT00039130 | COMPLETED | Leukemia; Lymphoma |
Alliance for Clinical Trials in Oncology |
2002-05 | PHASE2 |
| NCT00975897 | COMPLETED | Colorectal Cancer |
Medical Research Council |
2009-07 | PHASE2; PHASE3 |
| NCT00627666 | COMPLETED | Leukemia; Myelodysplastic Syndromes; Myelodysplastic/Myeloproliferative Neoplasms |
Asan Medical Center |
2003-01 | PHASE2 |
| NCT00112658 | COMPLETED | Pancreatic Cancer |
UNICANCER |
2004-11 | PHASE2; PHASE3 |
| NCT00640081 | COMPLETED | Colorectal Cancer |
Cheryl Pugh |
2007-07 | PHASE2 |
| NCT00112918 | COMPLETED | Colorectal Cancer |
Hoffmann-La Roche |
2004-12 | PHASE3 |
| NCT00467142 | COMPLETED | Colorectal Cancer |
Institut Bergonié |
2007-01-23 | PHASE2 |
| NCT00786643 | COMPLETED | Colorectal Cancer |
Accelerated Community Oncology Research Network |
2006-02 | PHASE2 |
| NCT00449163 | TERMINATED | Colorectal Cancer |
University of Miami |
2006-03-01 | PHASE2 |
| NCT00003298 | COMPLETED | Gastric Cancer |
ECOG-ACRIN Cancer Research Group |
1999-06-01 | PHASE2 |
| NCT00449137 | COMPLETED | Colorectal Cancer |
University of Miami |
2005-06 | PHASE1 |
| NCT00541112 | TERMINATED | Colorectal Cancer |
UNICANCER |
2007-10-29 | PHASE2 |
| NCT00089024 | COMPLETED | Pancreatic Cancer |
University of Nebraska |
2004-02-25 | PHASE2 |
| NCT00625092 | COMPLETED | Peritoneal Cavity Cancer |
Masonic Cancer Center, University of Minnesota |
2007-10 | PHASE1 |
| NCT00098774 | COMPLETED | Lymphoma |
Alliance for Clinical Trials in Oncology |
2004-10 | PHASE2 |
| NCT00275106 | TERMINATED | Lymphoma |
Children's Cancer and Leukaemia Group |
2004-09 | PHASE3 |
| NCT00448682 | TERMINATED | Gastric Cancer |
University of Miami |
2005-06 | PHASE2 |
| NCT00321828 | COMPLETED | Colorectal Cancer |
NSABP Foundation Inc |
2006-03 | PHASE2 |
| NCT00057811 | COMPLETED | Childhood Burkitt Lymphoma; Childhood Diffuse Large Cell Lymphoma; Childhood Immunoblastic Large Cell Lymphoma; Stage I Childhood Large Cell Lymphoma; Stage I Childhood Small Noncleaved Cell Lymphoma; Stage II Childhood Large Cell Lymphoma; Stage II Childhood Small Noncleaved Cell Lymphoma; Stage III Childhood Large Cell Lymphoma; Stage III Childhood Small Noncleaved Cell Lymphoma; Stage IV Childhood Large Cell Lymphoma; Stage IV Childhood Small Noncleaved Cell Lymphoma; Untreated Childhood Acute Lymphoblastic Leukemia |
Children's Oncology Group |
2004-06 | PHASE2 |
| NCT00884767 | UNKNOWN | Chemotherapeutic Agent Toxicity; Colorectal Cancer; Neurotoxicity |
Institut Cancerologie de l'Ouest |
2007-09 | PHASE2 |
| NCT00602329 | TERMINATED | Colorectal Cancer |
Abramson Cancer Center at Penn Medicine |
2006-02 | PHASE2 |
| NCT00408551 | UNKNOWN | Colorectal Cancer; Metastatic Cancer |
Goshen Health System |
2005-11 | PHASE2 |
| NCT00182715 | UNKNOWN | Colorectal Cancer |
Velindre NHS Trust |
2005-03 | PHASE3 |
| NCT00281944 | COMPLETED | Childhood Central Nervous System Choriocarcinoma; Childhood Central Nervous System Embryonal Tumor; Childhood Central Nervous System Germ Cell Tumor; Childhood Central Nervous System Germinoma; Childhood Central Nervous System Mixed Germ Cell Tumor; Childhood Central Nervous System Teratoma; Childhood Central Nervous System Yolk Sac Tumor; Recurrent Childhood Brain Stem Glioma; Recurrent Childhood Central Nervous System Embryonal Tumor; Unspecified Childhood Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2005-09 | PHASE1 |
| NCT00080990 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2004-02 | PHASE1 |
| NCT00096278 | COMPLETED | Colon Adenocarcinoma; Stage IIA Colon Cancer AJCC v7; Stage IIB Colon Cancer AJCC v7; Stage IIC Colon Cancer AJCC v7; Stage IIIA Colon Cancer AJCC v7; Stage IIIB Colon Cancer AJCC v7; Stage IIIC Colon Cancer AJCC v7 |
National Cancer Institute (NCI) |
2004-09-15 | PHASE3 |
| NCT00941174 | COMPLETED | Healthy |
The Hospital for Sick Children |
2008-09 | PHASE1 |
| NCT00042874 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2002-05 | PHASE1 |
| NCT00618501 | COMPLETED | Leukemia |
Asan Medical Center |
2005-10 | PHASE2 |
| NCT00004228 | COMPLETED | Lymphoma |
Children's Oncology Group |
2000-06 | PHASE3 |
| NCT00043121 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2002-06 | PHASE1 |
| NCT00296608 | COMPLETED | Colorectal Cancer |
Federation Francophone de Cancerologie Digestive |
1993-04 | PHASE3 |
| NCT00423696 | COMPLETED | Colorectal Cancer |
UNICANCER |
2006-03-23 | PHASE2 |
| NCT00588536 | COMPLETED | Langerhans Cell Histiocytosis |
Memorial Sloan Kettering Cancer Center |
1995-01 | PHASE2 |
| NCT00513188 | WITHDRAWN | Lymphoma |
University of Miami |
2007-02 | |
| NCT00003728 | UNKNOWN | Leukemia; Lymphoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1998-12 | PHASE3 |
| NCT00058201 | COMPLETED | Pancreatic Cancer |
Royal Liverpool University Hospital |
2001-07 | PHASE3 |
| NCT00381862 | COMPLETED | Colorectal Cancer; Nausea and Vomiting |
OHSU Knight Cancer Institute |
2006-06 | PHASE2 |
| NCT00513981 | COMPLETED | Brain and Central Nervous System Tumors; Sarcoma; Unspecified Childhood Solid Tumor, Protocol Specific |
Children's Cancer and Leukaemia Group |
2007-03 | PHASE1 |
| NCT00084838 | COMPLETED | Central Nervous System Tumor, Pediatric |
Dana-Farber Cancer Institute |
2003-02 | PHASE2 |
| NCT00628810 | COMPLETED | Colorectal Cancer |
Federation Francophone de Cancerologie Digestive |
2007-01 | PHASE2 |
| NCT00007878 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2000-09 | PHASE1 |
| NCT00061945 | COMPLETED | Acute Undifferentiated Leukemia; B-cell Adult Acute Lymphoblastic Leukemia; B-cell Childhood Acute Lymphoblastic Leukemia; L1 Adult Acute Lymphoblastic Leukemia; L1 Childhood Acute Lymphoblastic Leukemia; L2 Adult Acute Lymphoblastic Leukemia; L2 Childhood Acute Lymphoblastic Leukemia; Philadelphia Chromosome Negative Adult Precursor Acute Lymphoblastic Leukemia; Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia; Philadelphia Chromosome Positive Childhood Precursor Acute Lymphoblastic Leukemia; T-cell Adult Acute Lymphoblastic Leukemia; T-cell Childhood Acute Lymphoblastic Leukemia; Untreated Adult Acute Lymphoblastic Leukemia; Untreated Childhood Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2003-06 | PHASE1; PHASE2 |
| NCT00005945 | COMPLETED | Leukemia |
Children's Oncology Group |
2000-06 | PHASE3 |
| NCT00041132 | COMPLETED | Lymphoma |
SWOG Cancer Research Network |
2002-09 | PHASE2 |
| NCT00764907 | UNKNOWN | Leukemia |
University Hospital, Motol |
2002-11 | PHASE3 |
| NCT00056030 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
Alliance for Clinical Trials in Oncology |
2004-12 | PHASE2 |
| NCT00004252 | COMPLETED | Colorectal Cancer |
Pfizer |
1999-11 | PHASE3 |
| NCT00002756 | COMPLETED | Leukemia |
Children's Oncology Group |
1996-06 | PHASE2 |
| NCT00003835 | COMPLETED | Adenocarcinoma of the Colon; Stage III Colon Cancer |
National Cancer Institute (NCI) |
1999-05 | PHASE3 |
| NCT00003925 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
Barbara Ann Karmanos Cancer Institute |
1998-05 | PHASE1 |
| NCT00005585 | COMPLETED | Leukemia |
Children's Oncology Group |
2000-04 | PHASE3 |
| NCT00060411 | COMPLETED | Mucinous Adenocarcinoma of the Colon; Mucinous Adenocarcinoma of the Rectum; Recurrent Colon Cancer; Recurrent Rectal Cancer; Signet Ring Adenocarcinoma of the Colon; Signet Ring Adenocarcinoma of the Rectum; Stage IIIA Colon Cancer; Stage IIIA Rectal Cancer; Stage IIIB Colon Cancer; Stage IIIB Rectal Cancer; Stage IIIC Colon Cancer; Stage IIIC Rectal Cancer; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer |
National Cancer Institute (NCI) |
2003-06 | PHASE1 |
| NCT00004897 | TERMINATED | Esophageal Cancer |
Northwestern University |
1999-10 | PHASE2 |
| NCT00016302 | COMPLETED | T-cell Childhood Acute Lymphoblastic Leukemia; Untreated Childhood Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2001-04 | |
| NCT00016978 | COMPLETED | Colorectal Cancer |
National Cancer Institute (NCI) |
2001-04 | PHASE2 |
| NCT00043004 | TERMINATED | Colorectal Cancer; Metastatic Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2002-05 | PHASE2 |
| NCT00119301 | COMPLETED | Sarcoma |
Memorial Sloan Kettering Cancer Center |
2005-04 | PHASE1 |
| NCT00025337 | COMPLETED | Adenocarcinoma of the Colon; Adenocarcinoma of the Rectum; Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage III Colon Cancer; Stage III Rectal Cancer; Stage IV Colon Cancer; Stage IV Rectal Cancer |
National Cancer Institute (NCI) |
2001-09 | PHASE3 |
| NCT00098982 | COMPLETED | Colorectal Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2004-09 | PHASE1 |
| NCT00002463 | COMPLETED | Brain and Central Nervous System Tumors |
M.D. Anderson Cancer Center |
1989-02 | PHASE2 |
| NCT00002578 | COMPLETED | Lymphoma |
Roswell Park Cancer Institute |
1994-08 | PHASE2 |
| NCT00070122 | TERMINATED | Adenocarcinoma of the Colon; Adenocarcinoma of the Rectum; Recurrent Colon Cancer; Recurrent Rectal Cancer; Stage III Colon Cancer; Stage III Rectal Cancer; Stage IV Colon Cancer; Stage IV Rectal Cancer |
National Cancer Institute (NCI) |
2004-04 | PHASE3 |
| NCT00004233 | COMPLETED | Esophageal Cancer; Gastric Cancer |
SWOG Cancer Research Network |
2001-02 | PHASE2 |
| NCT00019864 | TERMINATED | Cardiac Toxicity; Sarcoma |
National Cancer Institute (NCI) |
2000-03 | PHASE2 |
| NCT00026364 | COMPLETED | Colorectal Cancer |
National Cancer Institute (NCI) |
2001-11 | PHASE1 |
| NCT00077233 | TERMINATED | Colorectal Cancer |
Alliance for Clinical Trials in Oncology |
2003-12 | PHASE3 |
| NCT00005036 | COMPLETED | Mucinous Adenocarcinoma of the Colon; Mucinous Adenocarcinoma of the Rectum; Recurrent Colon Cancer; Recurrent Rectal Cancer; Signet Ring Adenocarcinoma of the Colon; Signet Ring Adenocarcinoma of the Rectum; Stage IIIA Colon Cancer; Stage IIIA Rectal Cancer; Stage IIIB Colon Cancer; Stage IIIB Rectal Cancer; Stage IIIC Colon Cancer; Stage IIIC Rectal Cancer; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVB Colon Cancer; Stage IVB Rectal Cancer |
National Cancer Institute (NCI) |
1999-11 | PHASE3 |
| NCT00020943 | COMPLETED | Lymphoma |
Alliance for Clinical Trials in Oncology |
2001-06 | PHASE2 |
| NCT00002514 | COMPLETED | Leukemia |
Eastern Cooperative Oncology Group |
1993-05-07 | PHASE3 |
| NCT00022737 | COMPLETED | Childhood Acute Lymphoblastic Leukemia in Remission; Recurrent Childhood Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2002-10 | PHASE3 |
| NCT00262808 | COMPLETED | Colorectal Cancer |
University of Rochester |
2004-03 | PHASE2 |
| NCT00004231 | COMPLETED | Lymphoma |
Northwestern University |
1999-10 | PHASE2 |
| NCT00002551 | COMPLETED | Colorectal Cancer |
SWOG Cancer Research Network |
1994-03 | PHASE3 |
| NCT00002738 | COMPLETED | Leukemia; Lymphoma; Sarcoma |
Memorial Sloan Kettering Cancer Center |
1996-01 | PHASE2 |
| NCT00008294 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
Memorial Sloan Kettering Cancer Center |
2000-08 | PHASE1 |
| NCT00021073 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2001-05 | PHASE1 |
| NCT00002716 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
Alliance for Clinical Trials in Oncology |
1996-01 | PHASE3 |
| NCT00049569 | COMPLETED | L1 Childhood Acute Lymphoblastic Leukemia; L2 Childhood Acute Lymphoblastic Leukemia; Non-T, Non-B Childhood Acute Lymphoblastic Leukemia; Recurrent Childhood Acute Lymphoblastic Leukemia; T-cell Childhood Acute Lymphoblastic Leukemia |
National Cancer Institute (NCI) |
2003-01 | |
| NCT00070434 | WITHDRAWN | Colorectal Cancer |
SWOG Cancer Research Network |
2004-08 | PHASE2 |
| NCT00416767 | COMPLETED | Gastrointestinal Carcinoid Tumor; Islet Cell Tumor; Neoplastic Syndrome |
Federation Francophone de Cancerologie Digestive |
2004-05 | PHASE2 |
| NCT00268333 | COMPLETED | Colorectal Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2005-08 | PHASE2 |
| NCT00416819 | COMPLETED | Brain and Central Nervous System Tumors; Lymphoma |
University of California, San Francisco |
2003-09 | |
| NCT00003834 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
Alliance for Clinical Trials in Oncology |
1999-03 | PHASE2 |
| NCT00066274 | COMPLETED | Colorectal Cancer |
UNICANCER |
2002-07-23 | PHASE2 |
| NCT00085163 | COMPLETED | Colorectal Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2004-03 | PHASE3 |
| NCT00023998 | COMPLETED | Metastatic Osteosarcoma |
National Cancer Institute (NCI) |
2001-07 | PHASE2 |
| NCT00004005 | COMPLETED | Carcinoma of Unknown Primary; Colorectal Cancer; Unspecified Adult Solid Tumor, Protocol Specific; Unspecified Childhood Solid Tumor, Protocol Specific |
St. Jude Children's Research Hospital |
1998-09 | PHASE2 |
| NCT00004860 | COMPLETED | Colorectal Cancer |
Eastern Cooperative Oncology Group |
2000-10-09 | PHASE2 |
| NCT00002524 | COMPLETED | Lymphoma |
M.D. Anderson Cancer Center |
1993-06 | PHASE2 |
| NCT00005979 | COMPLETED | Colorectal Cancer |
UNICANCER |
1998-07-22 | PHASE3 |
| NCT00004931 | COMPLETED | Stage II Colon Cancer; Stage III Colon Cancer |
National Cancer Institute (NCI) |
2000-02 | PHASE3 |
| NCT00103103 | TERMINATED | Gastric Cancer |
California Cancer Consortium |
2005-03 | PHASE2 |
| NCT00003049 | COMPLETED | Pancreatic Cancer |
Mayo Clinic |
1997-05 | PHASE3 |
| NCT00039208 | COMPLETED | Colorectal Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2002-02 | PHASE2 |
| NCT00005596 | COMPLETED | Leukemia |
Children's Oncology Group |
2000-04 | PHASE3 |
| NCT00080951 | COMPLETED | Colorectal Cancer |
Alliance for Clinical Trials in Oncology |
2004-03 | PHASE2 |
| NCT00064181 | COMPLETED | Colorectal Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2003-05 | PHASE3 |
| NCT00052585 | TERMINATED | Adenocarcinoma of the Colon; Adenocarcinoma of the Rectum; Mucinous Adenocarcinoma of the Colon; Mucinous Adenocarcinoma of the Rectum; Recurrent Colon Cancer; Recurrent Rectal Cancer; Signet Ring Adenocarcinoma of the Colon; Signet Ring Adenocarcinoma of the Rectum; Stage IV Colon Cancer; Stage IV Rectal Cancer |
National Cancer Institute (NCI) |
2002-10 | PHASE2 |
| NCT00055822 | COMPLETED | Colorectal Cancer |
The University of Texas Health Science Center at San Antonio |
2002-10 | PHASE1; PHASE2 |
| NCT00003594 | COMPLETED | Colorectal Cancer |
Alliance for Clinical Trials in Oncology |
1998-10 | PHASE3 |
| NCT00026273 | COMPLETED | Colorectal Cancer |
Pfizer |
2001-01 | PHASE3 |
| NCT00002704 | COMPLETED | Leukemia |
National Cancer Institute (NCI) |
1996-01 | PHASE2 |
| NCT00023751 | COMPLETED | Colorectal Cancer |
Alliance for Clinical Trials in Oncology |
2001-07 | PHASE2 |
| NCT00016952 | COMPLETED | Colorectal Cancer |
Alliance for Clinical Trials in Oncology |
2001-04 | PHASE2 |
| NCT00003215 | COMPLETED | Lymphoma |
Swiss Cancer Institute |
1997-04 | PHASE3 |
| NCT00002494 | COMPLETED | Leukemia; Lymphoma |
Alliance for Clinical Trials in Oncology |
1992-05 | PHASE2 |
| NCT00005977 | COMPLETED | Leukemia; Lymphoma |
Children's Oncology Group |
2000-09 | PHASE3 |
| NCT00002700 | COMPLETED | Leukemia; Lymphoma |
European Organisation for Research and Treatment of Cancer - EORTC |
1995-08 | PHASE3 |
| NCT00003700 | COMPLETED | Leukemia |
Alliance for Clinical Trials in Oncology |
1999-01 | PHASE2 |
| NCT00004099 | TERMINATED | Gastric Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
1999-07 | PHASE3 |
| NCT00020917 | COMPLETED | Colorectal Cancer |
Memorial Sloan Kettering Cancer Center |
2001-02 | PHASE2 |
| NCT00002801 | COMPLETED | Colorectal Cancer |
Memorial Sloan Kettering Cancer Center |
1996-04 | PHASE1 |
| NCT00587873 | COMPLETED | Hodgkin's Disease |
Memorial Sloan Kettering Cancer Center |
1994-03 | PHASE2 |
| NCT00002571 | COMPLETED | Lymphoma |
SWOG Cancer Research Network |
1994-06 | PHASE2 |
| NCT00003799 | COMPLETED | Adenocarcinoma of the Rectum; Mucinous Adenocarcinoma of the Rectum; Signet Ring Adenocarcinoma of the Rectum; Stage IIA Rectal Cancer; Stage IIB Rectal Cancer; Stage IIC Rectal Cancer; Stage IIIA Rectal Cancer; Stage IIIB Rectal Cancer; Stage IIIC Rectal Cancer |
National Cancer Institute (NCI) |
1999-05 | PHASE1 |
| NCT00005068 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
Mayo Clinic |
2000-01 | PHASE1 |
| NCT00016198 | COMPLETED | Colorectal Cancer |
Prologue Research International |
2001-05 | PHASE2 |
| NCT00002523 | COMPLETED | Colorectal Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
1993-04 | PHASE3 |
| NCT00006038 | COMPLETED | Esophageal Cancer; Gastric Cancer |
Memorial Sloan Kettering Cancer Center |
2000-02 | PHASE2 |
| NCT00002471 | COMPLETED | Leukemia; Lymphoma |
Memorial Sloan Kettering Cancer Center |
1990-02 | PHASE2 |
| NCT00006015 | TERMINATED | Colorectal Cancer |
National Cancer Institute (NCI) |
2000-05 | PHASE2 |
| NCT00003783 | COMPLETED | Leukemia |
Children's Oncology Group |
1999-03 | PHASE2 |
| NCT00003671 | COMPLETED | Leukemia |
Children's Oncology Group |
1998-12 | PHASE2 |
| NCT00002816 | COMPLETED | Leukemia |
Children's Oncology Group |
1996-12 | PHASE3 |
| NCT00004127 | COMPLETED | Esophageal Cancer; Gastric Cancer |
University of Chicago |
2000-02 | PHASE2 |
| NCT00023868 | TERMINATED | Colorectal Cancer; Metastatic Cancer |
American College of Radiology Imaging Network |
2001-11-01 | PHASE3 |
| NCT00005608 | TERMINATED | Breast Cancer |
Northwestern University |
2000-02 | PHASE2 |
| NCT00002489 | COMPLETED | Extragonadal Germ Cell Tumor; Ovarian Cancer |
Memorial Sloan Kettering Cancer Center |
1991-10 | PHASE2 |
| NCT00004913 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
Northwestern University |
2000-01 | PHASE1 |
| NCT00006103 | COMPLETED | Colorectal Cancer |
Alliance for Clinical Trials in Oncology |
2000-07 | PHASE3 |
| NCT00003287 | COMPLETED | Colorectal Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
1998-03 | PHASE3 |
| NCT00003018 | COMPLETED | Pancreatic Cancer |
SWOG Cancer Research Network |
1997-09 | PHASE2 |
| NCT00006050 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
UNICANCER |
1999-04-04 | PHASE2 |
| NCT00002665 | COMPLETED | Leukemia; Neutropenia; Thrombocytopenia |
SWOG Cancer Research Network |
1995-07 | PHASE2 |
| NCT00003331 | COMPLETED | Chronic Myeloproliferative Disorders; Leukemia; Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes; Precancerous Condition; Unspecified Adult Solid Tumor, Protocol Specific |
NYU Langone Health |
1998-01 | PHASE1 |
| NCT00004102 | COMPLETED | Colorectal Cancer |
NYU Langone Health |
1999-01 | PHASE2 |
| NCT00002552 | COMPLETED | Lymphoma; Multiple Myeloma and Plasma Cell Neoplasm |
Barbara Ann Karmanos Cancer Institute |
1993-10 | PHASE2 |
| NCT01230983 | COMPLETED | Cardiac Toxicity; Leukemia; Lymphoma |
Children's Oncology Group |
1996-06 | PHASE3 |
| NCT00021398 | COMPLETED | Colorectal Cancer |
Fox Chase Cancer Center |
1996-07 | PHASE2 |
| NCT00004885 | COMPLETED | Colorectal Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
1999-07 | PHASE3 |
| NCT00005988 | COMPLETED | Graft Versus Host Disease; Leukemia; Lymphoma; Myelodysplastic Syndromes; Myeloma |
Dana-Farber Cancer Institute |
2000-02 | PHASE1 |
| NCT00002590 | COMPLETED | Lymphoma |
Children's Oncology Group |
1994-07 | PHASE2 |
| NCT00003956 | COMPLETED | Lymphoma; Unspecified Adult Solid Tumor, Protocol Specific |
Memorial Sloan Kettering Cancer Center |
1999-04 | PHASE1 |
| NCT00002783 | COMPLETED | Gastric Cancer |
Memorial Sloan Kettering Cancer Center |
1996-05 | PHASE2 |
| NCT00002570 | COMPLETED | Colorectal Cancer |
NCIC Clinical Trials Group |
1994-07-15 | PHASE3 |
| NCT00005944 | TERMINATED | Colorectal Cancer; Metastatic Cancer; Primary Peritoneal Cavity Cancer |
UNICANCER |
1999-07-01 | PHASE2 |
| NCT00005641 | TERMINATED | Chronic Myeloproliferative Disorders; Graft Versus Host Disease; Leukemia; Multiple Myeloma and Plasma Cell Neoplasm; Myelodysplastic Syndromes |
H. Lee Moffitt Cancer Center and Research Institute |
1997-09 | PHASE2 |
| NCT00002618 | COMPLETED | Lymphoma |
Children's Oncology Group |
1994-12 | PHASE3 |
| NCT00002785 | COMPLETED | Leukemia |
Children's Oncology Group |
1996-07 | PHASE2 |
| NCT00002865 | COMPLETED | Leukemia |
Wake Forest University Health Sciences |
1995-04 | PHASE2 |
| NCT00002691 | COMPLETED | Lymphoma |
Memorial Sloan Kettering Cancer Center |
1995-08 | PHASE2 |
| NCT00002955 | COMPLETED | Pancreatic Cancer |
University of Southern California |
1995-08 | PHASE2 |
| NCT00003776 | COMPLETED | Sarcoma |
Memorial Sloan Kettering Cancer Center |
1998-12 | PHASE2 |
| NCT00002593 | COMPLETED | Colorectal Cancer |
SWOG Cancer Research Network |
1994-12 | PHASE3 |
| NCT00002722 | COMPLETED | Gastric Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
1996-01 | PHASE2 |
| NCT00425152 | COMPLETED | Colorectal Cancer |
NSABP Foundation Inc |
1989-07 | PHASE3 |
| NCT00019513 | COMPLETED | Colorectal Cancer; Esophageal Cancer; Extrahepatic Bile Duct Cancer; Gallbladder Cancer; Liver Cancer; Lung Cancer; Lymphoma; Pancreatic Cancer; Small Intestine Cancer; Unspecified Adult Solid Tumor, Protocol Specific |
National Institutes of Health Clinical Center (CC) |
1998-08 | PHASE1 |
| NCT00002692 | UNKNOWN | Colorectal Cancer; Metastatic Cancer |
Medical Research Council |
1994-12 | PHASE3 |
| NCT00000724 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE3 | |
| NCT00002120 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
U.S. Bioscience |
PHASE1 | |
| NCT00001013 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE3 | |
| NCT00025142 | COMPLETED | Colorectal Cancer |
Stanford University |
2001-07 | PHASE2 |
| NCT00000643 | COMPLETED | Toxoplasmosis, Cerebral; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE2 | |
| NCT00002103 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
U.S. Bioscience |
||
| NCT00006786 | COMPLETED | Colorectal Cancer |
Eastern Cooperative Oncology Group |
2000-11 | PHASE2 |
| NCT00001016 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE3 | |
| NCT00003001 | UNKNOWN | Colorectal Cancer |
Stony Brook University |
1997-04 | PHASE1; PHASE2 |
| NCT00000703 | COMPLETED | Lymphoma, Non-Hodgkin; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
||
| NCT00004206 | UNKNOWN | Ovarian Cancer |
University of Leicester |
1999-09 | PHASE2 |
| NCT00001449 | COMPLETED | Neoplasms |
National Cancer Institute (NCI) |
1995-09 | PHASE1 |
| NCT00001014 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE3 | |
| NCT00276757 | COMPLETED | Childhood Langerhans Cell Histiocytosis |
Histiocyte Society |
2001-04 | |
| NCT00020501 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
National Institutes of Health Clinical Center (CC) |
2001-03 | PHASE3 |
| NCT00005607 | UNKNOWN | Esophageal Cancer; Gastric Cancer |
Robert H. Lurie Cancer Center |
2000-02 | PHASE2 |
| NCT00002002 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
Lederle Laboratories |
||
| NCT00002531 | UNKNOWN | Leukemia |
Johann Wolfgang Goethe University Hospital |
1993-01 | PHASE2 |
| NCT00042861 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2002-08 | PHASE1 |
| NCT00066846 | COMPLETED | Colorectal Cancer |
National Cancer Institute (NCI) |
2003-08 | PHASE2 |
| NCT00027833 | UNKNOWN | Colorectal Cancer |
Herbert Irving Comprehensive Cancer Center |
2001-12 | PHASE2 |
| NCT00008060 | COMPLETED | Colorectal Cancer |
Medical Research Council |
2000-05 | PHASE3 |
| NCT00003260 | UNKNOWN | Colorectal Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
1998-01 | PHASE3 |
| NCT00002434 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
U.S. Bioscience |
||
| NCT00009828 | WITHDRAWN | Unspecified Adult Solid Tumor, Protocol Specific |
University of Pittsburgh |
1999-12 | PHASE1 |
| NCT00006112 | UNKNOWN | Carcinoma of the Appendix; Colorectal Cancer; Primary Peritoneal Cavity Cancer |
Gustave Roussy, Cancer Campus, Grand Paris |
1996-01 | PHASE2 |
| NCT00049101 | COMPLETED | Colorectal Cancer |
Memorial Sloan Kettering Cancer Center |
2002-08 | PHASE1; PHASE2 |
| NCT00004164 | UNKNOWN | Head and Neck Cancer |
Dana-Farber Cancer Institute |
1999-08 | PHASE2 |
| NCT00003273 | WITHDRAWN | Brain and Central Nervous System Tumors; Neuroblastoma; Retinoblastoma; Sarcoma |
NYU Langone Health |
1997-11 | PHASE2 |
| NCT00020488 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Cancer Institute (NCI) |
2001-02 | PHASE1 |
| NCT00010088 | UNKNOWN | Extrahepatic Bile Duct Cancer; Pancreatic Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
1999-01 | PHASE2 |
| NCT00021281 | UNKNOWN | Colorectal Cancer |
Jonsson Comprehensive Cancer Center |
2000-12 | PHASE3 |
| NCT00019760 | COMPLETED | Recurrent Colon Cancer; Liver Metastases; Stage IV Rectal Cancer; Recurrent Rectal Cancer; Stage IV Colon Cancer |
National Institutes of Health Clinical Center (CC) |
1999-04 | PHASE2 |
| NCT00003305 | COMPLETED | Leukemia |
Genzyme, a Sanofi Company |
1997-07 | PHASE2 |
| NCT00091312 | UNKNOWN | Colorectal Cancer |
Federation Francophone de Cancerologie Digestive |
2004-06 | PHASE3 |
| NCT00000714 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE3 | |
| NCT00524706 | UNKNOWN | Colorectal Cancer |
Shizuoka Cancer Center |
2007-08 | PHASE1; PHASE2 |
| NCT00002317 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
U.S. Bioscience |
||
| NCT00274872 | UNKNOWN | Colorectal Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2004-01 | PHASE2; PHASE3 |
| NCT00006115 | UNKNOWN | Colorectal Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
1999-04 | PHASE2 |
| NCT00016133 | COMPLETED | Colorectal Cancer |
Intracel |
2001-03 | PHASE1; PHASE2 |
| NCT00000674 | COMPLETED | Toxoplasmosis, Cerebral; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
||
| NCT00002532 | UNKNOWN | Leukemia |
Hannover Medical School |
1993-01 | PHASE2 |
| NCT00006479 | UNKNOWN | Colorectal Cancer; Metastatic Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2000-09 | PHASE3 |
| NCT00003446 | COMPLETED | Colorectal Cancer |
Grupo Oncologico Cooperativo del Sur |
1997-12 | PHASE2 |
| NCT00004150 | COMPLETED | Colorectal Cancer |
Robert Roessle Klinik |
1999-03 | PHASE3 |
| NCT00000658 | COMPLETED | Lymphoma, Non-Hodgkin; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE3 | |
| NCT00323583 | UNKNOWN | Adenocarincoma of Pancreas; Stage III Pancreatic Cancer; Stage IVA Pancreatic Cancer; Stage IVB Pancreatic Cancer |
Seattle Cancer Treatment and Wellness Center |
2006-05 | PHASE2 |
| NCT00571740 | WITHDRAWN | Colorectal Cancer |
Alliance for Clinical Trials in Oncology |
PHASE2 | |
| NCT00000973 | COMPLETED | Toxoplasmosis, Cerebral; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE1 | |
| NCT00062426 | COMPLETED | Colorectal Cancer |
Prologue Research International |
2003-05 | PHASE3 |
| NCT00040690 | COMPLETED | Leukemia; Lymphoma |
Medical Research Council |
2008-11 | PHASE2 |
| NCT00002793 | UNKNOWN | Colorectal Cancer; Metastatic Cancer |
Johann Wolfgang Goethe University Hospital |
1991-01 | PHASE3 |
| NCT00045539 | COMPLETED | Lymphoma |
New Approaches to Brain Tumor Therapy Consortium |
2002-10 | PHASE2 |
| NCT00000723 | TERMINATED | Lymphoma, Non-Hodgkin; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
||
| NCT00000794 | COMPLETED | Toxoplasmosis, Cerebral; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE2 | |
| NCT00039611 | COMPLETED | Colorectal Cancer |
National Cancer Institute (NCI) |
2002-05 | |
| NCT00002893 | UNKNOWN | Colorectal Cancer |
Medical Research Council |
1995-06 | PHASE3 |
| NCT00000966 | COMPLETED | Toxoplasmosis, Cerebral; HIV Infections |
Pfizer |
PHASE1 | |
| NCT00003063 | UNKNOWN | Colorectal Cancer |
European Institute of Oncology |
1991-11 | PHASE3 |
| NCT00103298 | COMPLETED | Colorectal Cancer; Metastatic Cancer |
National Cancer Institute (NCI) |
2004-12 | PHASE2 |
| NCT00000998 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE1 | |
| NCT00003558 | UNKNOWN | Carcinoma of Unknown Primary |
Academisch Ziekenhuis Maastricht |
1998-08 | PHASE3 |
| NCT00497107 | UNKNOWN | Colorectal Cancer |
Iwate Medical University |
2007-07 | PHASE3 |
| NCT00438737 | UNKNOWN | Colorectal Cancer; Metastatic Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2007-01 | PHASE2 |
| NCT00009815 | WITHDRAWN | Unspecified Adult Solid Tumor, Protocol Specific |
University of Pittsburgh |
1999-12 | PHASE1 |
| NCT00002557 | UNKNOWN | Lymphoma |
National Cancer Institute (NCI) |
1993-06 | PHASE2 |
| NCT00005860 | COMPLETED | Cancer |
Memorial Sloan Kettering Cancer Center |
2000-04 | PHASE1 |
| NCT00046995 | UNKNOWN | Colorectal Cancer |
Groupe Regional d'Etudes du Cancer Colorectal |
2001-05 | PHASE3 |
| NCT00006468 | UNKNOWN | Colorectal Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2000-01 | PHASE3 |
| NCT00003422 | COMPLETED | Colorectal Cancer |
Medical Research Council |
1998-01 | PHASE3 |
| NCT00002476 | COMPLETED | Head and Neck Cancer |
Cancer Research UK |
1990-01 | PHASE3 |
| NCT00008281 | UNKNOWN | Colorectal Cancer |
Sanofi |
2000-10 | PHASE3 |
| NCT00000689 | COMPLETED | Lymphoma, Non-Hodgkin; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE1 | |
| NCT00072553 | UNKNOWN | Colorectal Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2003-09 | PHASE2 |
| NCT00000730 | TERMINATED | Pneumonia, Pneumocystis Carinii; HIV Infections |
National Institute of Allergy and Infectious Diseases (NIAID) |
PHASE3 | |
| NCT00002102 | COMPLETED | Pneumonia, Pneumocystis Carinii; HIV Infections |
U.S. Bioscience |
||
| NCT00513266 | UNKNOWN | Colorectal Cancer; Metastatic Cancer |
Centre Hospitalier Universitaire Vaudois |
2007-06 | PHASE2 |
| NCT00075595 | UNKNOWN | Colorectal Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2002-06 | PHASE2 |
| NCT00075738 | UNKNOWN | Esophageal Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2003-10 | PHASE2 |
| NCT00010075 | UNKNOWN | Breast Cancer |
GERCOR - Multidisciplinary Oncology Cooperative Group |
2000-01 | PHASE2 |
(data from https://clinicaltrials.gov, updated on 2026-08-25)
Check the
Calcium folinate (Leucovorin calcium)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Compliance for Clinical Use
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
Jump to
- Calcium folinate (Leucovorin calcium) Solubility in DMSO
- Calcium folinate (Leucovorin calcium) Storage
- Calcium folinate (Leucovorin calcium) Stability
- Calcium folinate (Leucovorin calcium) Molecular Weight
- Calcium folinate (Leucovorin calcium) CAS Number
- Calcium folinate (Leucovorin calcium) Chemical Structure (2D and 3D)
- Calcium folinate (Leucovorin calcium) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.