2D Structure
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2D chemical structural formula diagram.
3D Structure
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This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
Cabozantinib (XL184)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | |
|---|---|---|
| CAS Number | 849217-68-1 | |
| Molecular Formula |
C28H24FN3O5 |
|
| Molecular Weight (MW) | 501.51 | |
| SMILES | COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F | |
| InChIKey | ONIQOQHATWINJY-UHFFFAOYSA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(199.39 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(199.39 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(199.39 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(199.39 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(199.39 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Cabozantinib (XL184) Mechanism of Action: VEGFR2 Inhibition in Endothelial Cells Research
- Cabozantinib (XL184) Clinical Trials
- Cabozantinib (XL184): Selectivity & Specificity
- Cabozantinib (XL184) Working Concentration | Cell Culture | Treatment
- Cabozantinib (XL184) Solubility in DMSO
- Cabozantinib (XL184) Stock Solution
- Cabozantinib (XL184) Storage
- Cabozantinib (XL184) Stability
- Cabozantinib (XL184) Combination Database
- Cabozantinib (XL184) Molecular Weight
- Cabozantinib (XL184) SMILES
- Cabozantinib (XL184) CAS Number
- Cabozantinib (XL184) IC50 for Cell-based and Cell-free Assays
- Cabozantinib (XL184) Sigma (SML3914)? Try a better option.
- Cabozantinib (XL184) MedChemExpress (HY-13016)? Try a better option.
- Cabozantinib (XL184) APExBIO (A2977)? Try a better option.
- Cabozantinib (XL184) Cayman (18464)? Try a better option.
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- Cabozantinib (XL184) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.