Home Biosimilar Antibodies Protein Tyrosine Kinase CSF-1R Cabiralizumab (Anti-CSF1R / M-CSFR / CD115)
For research use only. Not for use in humans.

Cabiralizumab (Anti-CSF1R / M-CSFR / CD115)

Synonyms: FPA 008

Cabiralizumab (Anti-CSF1R / M-CSFR / CD115) is an monoclonal antibody (MAb) targeting CSF1R. It can be used in the research of rheumatoid arthritis (RA), melanoma, kidney cancer, or non-small cell lung cancer. MW :146.3 KD.

Cabiralizumab (Anti-CSF1R / M-CSFR / CD115)

Quality Control

Batch: A264401 Purity: 99% Protein concentration: 5.74mg/ml Endotoxin Level: ＜1EU/mg
99

Specificity

Name Citation CSF-1R Others
Linifanib (ABT-869) 33 VEGFR1/FLT1,FLT3,VEGFR2/KDR
ENMD-2076 9 FLT3,RET,Aurora A
OSI-930 7 FLT1,KDR,LCK
GW2580 17
Agerafenib (CEP-32496) 6 RET,PDGFRβ,LCK
Vimseltinib 0 c-Kit
Edicotinib(JNJ-40346527) 2
Chiauranib 0 c-Kit,VEGFR2,Aurora B
ARRY-382 0
Elzovantinib (TPX-0022) 0 SRC,MET
Ki20227 1 VEGFR2,PDGFRβ,c-Kit
Sulfatinib 1 VEGFR3,VEGFR1,FGFR1
PLX5622 14 FLT3,KIT,AURKC
PRN1371 2 FGFR1,FGFR2,FGFR3
Sotuletinib (BLZ945) 34
Pimicotinib 0
CSF1R-IN-1 1
AZD7507 0
PDGFR inhibitor 1 4 PDGFR,Kit,VEGFR2
Expand to Check More
1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description
Cabiralizumab (Anti-CSF1R / M-CSFR / CD115) is an monoclonal antibody (MAb) targeting CSF1R. It can be used in the research of rheumatoid arthritis (RA), melanoma, kidney cancer, or non-small cell lung cancer. MW :146.3 KD.
References

Product Details

CAS No. 1613144-80-1
Molecular Weight 146.3
Isotype Human IgG4SP
Source CHO
Purification AKTA
Sterility 0.2 μM filtered
Formulation 100 mM Pro-Ac, 20mM Arg, pH5.0
Storage
(From the date of receipt)		 Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

Tech Support

Handling Instructions

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