L-Buthionine-(S,R)-sulfoximine (L-BSO): Mechanism of Action

L-Buthionine-(S,R)-sulfoximine (L-BSO) MOA:Targeting γ-GCS/Glutathione Biosynthesis Pathway for Cancer Therapy and Sensitization

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L-BSO is a potent γ-GCS inhibitor. It affects AKT and MAPK pathways by depleting GSH to increase ROS, promoting apoptosis.

Primary Applications and Mechanism of Action