SMILES:
CCC(=C(C1=CC=C(C=C1)C=CC(=O)O)C2=CC3=C(C=C2)NN=C3)C4=C(C=C(C=C4)F)Cl
Chemical Structure
Check the
Brilanestrant (GDC-0810)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 1365888-06-7 | |
|---|---|---|
| Molecular Formula |
C26H20ClFN2O2 |
|
| Molecular Weight (MW) | 446.90 | |
| SMILES | CCC(=C(C1=CC=C(C=C1)C=CC(=O)O)C2=CC3=C(C=C2)NN=C3)C4=C(C=C(C=C4)F)Cl |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
89 mg/mL
(199.14 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 89 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Brilanestrant (GDC-0810) Clinical Trials
- Brilanestrant (GDC-0810) Solubility in DMSO
- Brilanestrant (GDC-0810) Stock Solution
- Brilanestrant (GDC-0810) Storage
- Brilanestrant (GDC-0810) Stability
- Brilanestrant (GDC-0810) Molecular Weight
- Brilanestrant (GDC-0810) CAS Number
- Brilanestrant (GDC-0810) Chemical Structure (2D and 3D)
- Brilanestrant (GDC-0810) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.