BI-2865 is a potent KRAS/P-gp inhibitor. It affects ERK/AKT signaling pathways, by reducing KRAS-GTP, inhibiting MDR and growth.
Comprehensive IC50 Values for BI-2865 Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.
BI-2865 is a potent KRAS/P-gp inhibitor. It affects ERK/AKT signaling pathways, by reducing KRAS-GTP, inhibiting MDR and growth.