Molecular Weight: 487.53 g/mol
Chemical Structure
Check the
Avitinib (Abivertinib)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
97 mg/mL
(198.96 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 97 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
| IUPAC Name | N-[3-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide | |
|---|---|---|
| CAS Number | 1557267-42-1 | |
| Molecular Formula |
C26H26FN7O2 |
|
| Molecular Weight (MW) | 487.53 | |
| SMILES | CN1CCN(CC1)C2=C(C=C(C=C2)NC3=NC4=C(C=CN4)C(=N3)OC5=CC=CC(=C5)NC(=O)C=C)F | |
| InChIKey | UOFYSRZSLXWIQB-UHFFFAOYSA-N |
- Avitinib (Abivertinib) Clinical Trials
- Avitinib (Abivertinib) Solubility in DMSO
- Avitinib (Abivertinib) Stock Solution
- Avitinib (Abivertinib) Storage
- Avitinib (Abivertinib) Stability
- Avitinib (Abivertinib) SMILES
- Avitinib (Abivertinib) CAS Number
- Avitinib (Abivertinib) Chemical Structure (2D and 3D)
- Avitinib (Abivertinib) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.